Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.

Kuatsjah, Eugene; Zahn, Michael; Chen, Xiangyang; Kato, Ryo; Hinchen, Daniel J; Konev, Mikhail O; Katahira, Rui; Orr, Christian; Wagner, Armin; Zou, Yike; Haugen, Stefan J; Ramirez, Kelsey J; Michener, Joshua K; Pickford, Andrew R; Kamimura, Naofumi; Masai, Eiji; Houk, K N; McGeehan, John E; Beckham, Gregg T.

Proc Natl Acad Sci U S A ; 120(4): e2212246120, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36652470

2.

Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440.

McNaught, Kevin J; Kuatsjah, Eugene; Zahn, Michael; Prates, Érica T; Shao, Huiling; Bentley, Gayle J; Pickford, Andrew R; Gruber, Josephine N; Hestmark, Kelley V; Jacobson, Daniel A; Poirier, Brenton C; Ling, Chen; San Marchi, Myrsini; Michener, William E; Nicora, Carrie D; Sanders, Jacob N; Szostkiewicz, Caralyn J; Velickovic, Dusan; Zhou, Mowei; Munoz, Nathalie; Kim, Young-Mo; Magnuson, Jon K; Burnum-Johnson, Kristin E; Houk, K N; McGeehan, John E; Johnson, Christopher W; Beckham, Gregg T.

Metab Eng ; 76: 193-203, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36796578

3.

Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover.

Falconer, Adrian M D; Chan, Chun Ming; Gray, Joseph; Nagashima, Izuru; Holland, Robert A; Shimizu, Hiroki; Pickford, Andrew R; Rowan, Andrew D; Wilkinson, David J.

J Biol Chem ; 294(26): 10266-10277, 2019 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-31110047

4.

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions.

Phillips, Jack O; Butt, Louise E; Henderson, Charlotte A; Devonshire, Martin; Healy, Jess; Conway, Stuart J; Locker, Nicolas; Pickford, Andrew R; Vincent, Helen A; Callaghan, Anastasia J.

Nucleic Acids Res ; 46(14): e86, 2018 08 21.

Artigo em Inglês | MEDLINE | ID: mdl-29846708

5.

Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism.

Stone, Carlanne M; Butt, Louise E; Bufton, Joshua C; Lourenco, Daniel C; Gowers, Darren M; Pickford, Andrew R; Cox, Paul A; Vincent, Helen A; Callaghan, Anastasia J.

Nucleic Acids Res ; 45(8): 4655-4666, 2017 05 05.

Artigo em Inglês | MEDLINE | ID: mdl-28334892

6.

Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering.

Avilan, Luisana; Lichtenstein, Bruce R; König, Gerhard; Zahn, Michael; Allen, Mark D; Oliveira, Liliana; Clark, Matilda; Bemmer, Victoria; Graham, Rosie; Austin, Harry P; Dominick, Graham; Johnson, Christopher W; Beckham, Gregg T; McGeehan, John E; Pickford, Andrew R.

ChemSusChem ; 16(8): e202202277, 2023 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-36811288

7.

The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.

Arnold, Laurence H; Butt, Louise E; Prior, Stephen H; Read, Christopher M; Fields, Gregg B; Pickford, Andrew R.

J Biol Chem ; 286(52): 45073-82, 2011 Dec 30.

Artigo em Inglês | MEDLINE | ID: mdl-22030392

8.

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.

Erickson, Erika; Shakespeare, Thomas J; Bratti, Felicia; Buss, Bonnie L; Graham, Rosie; Hawkins, McKenzie A; König, Gerhard; Michener, William E; Miscall, Joel; Ramirez, Kelsey J; Rorrer, Nicholas A; Zahn, Michael; Pickford, Andrew R; McGeehan, John E; Beckham, Gregg T.

ChemSusChem ; 15(1): e202101932, 2022 Jan 10.

Artigo em Inglês | MEDLINE | ID: mdl-34587366

9.

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.

Erickson, Erika; Shakespeare, Thomas J; Bratti, Felicia; Buss, Bonnie L; Graham, Rosie; Hawkins, McKenzie A; König, Gerhard; Michener, William E; Miscall, Joel; Ramirez, Kelsey J; Rorrer, Nicholas A; Zahn, Michael; Pickford, Andrew R; McGeehan, John E; Beckham, Gregg T.

ChemSusChem ; 15(1): e202102517, 2022 Jan 10.

Artigo em Inglês | MEDLINE | ID: mdl-34914860

10.

Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity.

Erickson, Erika; Gado, Japheth E; Avilán, Luisana; Bratti, Felicia; Brizendine, Richard K; Cox, Paul A; Gill, Raj; Graham, Rosie; Kim, Dong-Jin; König, Gerhard; Michener, William E; Poudel, Saroj; Ramirez, Kelsey J; Shakespeare, Thomas J; Zahn, Michael; Boyd, Eric S; Payne, Christina M; DuBois, Jennifer L; Pickford, Andrew R; Beckham, Gregg T; McGeehan, John E.

Nat Commun ; 13(1): 7850, 2022 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-36543766

11.

Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI.

Erat, Michèle C; Schwarz-Linek, Ulrich; Pickford, Andrew R; Farndale, Richard W; Campbell, Iain D; Vakonakis, Ioannis.

J Biol Chem ; 285(44): 33764-70, 2010 Oct 29.

Artigo em Inglês | MEDLINE | ID: mdl-20739283

12.

Design and structure of stapled peptides binding to estrogen receptors.

Phillips, Chris; Roberts, Lee R; Schade, Markus; Bazin, Richard; Bent, Andrew; Davies, Nichola L; Moore, Rob; Pannifer, Andrew D; Pickford, Andrew R; Prior, Stephen H; Read, Christopher M; Scott, Andrew; Brown, David G; Xu, Bin; Irving, Stephen L.

J Am Chem Soc ; 133(25): 9696-9, 2011 Jun 29.

Artigo em Inglês | MEDLINE | ID: mdl-21612236

13.

Tuning the matrix metalloproteinase-1 degradability of peptide amphiphile nanofibers through supramolecular engineering.

Shi, Yejiao; Ferreira, Daniela S; Banerjee, Jayati; Pickford, Andrew R; Azevedo, Helena S.

Biomater Sci ; 7(12): 5132-5142, 2019 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-31576824

14.

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis.

Norouzi, Masoud; Pickford, Andrew R; Butt, Louise E; Vincent, Helen A; Callaghan, Anastasia J.

ACS Synth Biol ; 8(2): 207-215, 2019 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-30682244

15.

Using Small Angle X-Ray Scattering (SAXS) to Characterize the Solution Conformation and Flexibility of Matrix Metalloproteinases (MMPs).

Butt, Louise E; Holland, Robert A; Khunti, Nikul S; Quinn, Debra L; Pickford, Andrew R.

Methods Mol Biol ; 1579: 87-108, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28299734

16.

Structural insight into binding of Staphylococcus aureus to human fibronectin.

Pilka, Ewa S; Werner, Joern M; Schwarz-Linek, Ulrich; Pickford, Andrew R; Meenan, Nicola A G; Campbell, Iain D; Potts, Jennifer R.

FEBS Lett ; 580(1): 273-7, 2006 Jan 09.

Artigo em Inglês | MEDLINE | ID: mdl-16376343

17.

Gelatin binding to the 8F19F1 module pair of human fibronectin requires site-specific N-glycosylation.

Millard, Christopher J; Campbell, Iain D; Pickford, Andrew R.

FEBS Lett ; 579(20): 4529-34, 2005 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-16083879

18.

Development of an assay for the quantification of type I collagen synthesis in the guinea pig.

Quasnichka, Helen L; Tarlton, John F; Anderson-Mackenzie, Janet M; Billingham, Michael E J; Bailey, Allen J; Pickford, Andrew R.

J Immunol Methods ; 297(1-2): 133-41, 2005 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-15777937

19.

The gentle grip of a helping hand.

Pickford, Andrew R.

Structure ; 23(2): 249-50, 2015 Feb 03.

Artigo em Inglês | MEDLINE | ID: mdl-25651055

20.

Isotopic labeling of recombinant proteins from the methylotrophic yeast Pichia pastoris.

Pickford, Andrew R; O'Leary, Joanne M.

Methods Mol Biol ; 278: 17-33, 2004.

Artigo em Inglês | MEDLINE | ID: mdl-15317988

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Biochemical and structural characterization of a sphingomonad diarylpropane lyase for cofactorless deformylation.

Initiation of fatty acid biosynthesis in Pseudomonas putida KT2440.

Collagenolytic matrix metalloproteinases antagonize proteinase-activated receptor-2 activation, providing insights into extracellular matrix turnover.

High-density functional-RNA arrays as a versatile platform for studying RNA-based interactions.

Inhibition of homologous phosphorolytic ribonucleases by citrate may represent an evolutionarily conserved communicative link between RNA degradation and central metabolism.

Concentration-Dependent Inhibition of Mesophilic PETases on Poly(ethylene terephthalate) Can Be Eliminated by Enzyme Engineering.

The interface between catalytic and hemopexin domains in matrix metalloproteinase-1 conceals a collagen binding exosite.

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.

Comparative Performance of PETase as a Function of Reaction Conditions, Substrate Properties, and Product Accumulation.

Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity.

Implications for collagen binding from the crystallographic structure of fibronectin 6FnI1-2FnII7FnI.

Design and structure of stapled peptides binding to estrogen receptors.

Tuning the matrix metalloproteinase-1 degradability of peptide amphiphile nanofibers through supramolecular engineering.

Application of mRNA Arrays for the Production of mCherry Reporter-Protein Arrays for Quantitative Gene Expression Analysis.

Using Small Angle X-Ray Scattering (SAXS) to Characterize the Solution Conformation and Flexibility of Matrix Metalloproteinases (MMPs).

Structural insight into binding of Staphylococcus aureus to human fibronectin.

Gelatin binding to the 8F19F1 module pair of human fibronectin requires site-specific N-glycosylation.

Development of an assay for the quantification of type I collagen synthesis in the guinea pig.

The gentle grip of a helping hand.

Isotopic labeling of recombinant proteins from the methylotrophic yeast Pichia pastoris.