Detalhe da pesquisa
1.
COQ4 is required for the oxidative decarboxylation of the C1 carbon of coenzyme Q in eukaryotic cells.
Mol Cell
; 84(5): 981-989.e7, 2024 Mar 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-38295803
2.
An organic O donor for biological hydroxylation reactions.
Proc Natl Acad Sci U S A
; 121(13): e2321242121, 2024 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507448
3.
Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2.
Nat Chem Biol
; 19(2): 206-217, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36280795
4.
Diversification of Ubiquinone Biosynthesis via Gene Duplications, Transfers, Losses, and Parallel Evolution.
Mol Biol Evol
; 40(10)2023 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37788637
5.
Activation of Coq6p, a FAD Monooxygenase Involved in Coenzyme Q Biosynthesis, by Adrenodoxin Reductase/Ferredoxin.
Chembiochem
; 25(5): e202300738, 2024 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38141230
6.
Structural Reconstruction of E. coli Ubi Metabolon Using an AlphaFold2-Based Computational Framework.
J Chem Inf Model
; 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38710096
7.
Cerebellar Ataxia and Coenzyme Q Deficiency through Loss of Unorthodox Kinase Activity.
Mol Cell
; 63(4): 608-620, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27499294
8.
Identification and characterization of a noncanonical menaquinone-linked formate dehydrogenase.
J Biol Chem
; 298(2): 101384, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34748728
9.
Towards Molecular Understanding of the Functional Role of UbiJ-UbiK2 Complex in Ubiquinone Biosynthesis by Multiscale Molecular Modelling Studies.
Int J Mol Sci
; 23(18)2022 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36142227
10.
Recent advances in the metabolic pathways and microbial production of coenzyme Q.
World J Microbiol Biotechnol
; 38(4): 58, 2022 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35178585
11.
The Biosynthetic Pathway of Ubiquinone Contributes to Pathogenicity of Francisella novicida.
J Bacteriol
; 203(23): e0040021, 2021 11 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34543102
12.
The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa.
J Biol Chem
; 295(27): 9021-9032, 2020 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32409583
13.
The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ.
J Biol Chem
; 292(28): 11937-11950, 2017 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28559279
14.
The COQ2 genotype predicts the severity of coenzyme Q10 deficiency.
Hum Mol Genet
; 25(19): 4256-4265, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27493029
15.
Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6.
PLoS Comput Biol
; 12(1): e1004690, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808124
16.
Coq6 is responsible for the C4-deamination reaction in coenzyme Q biosynthesis in Saccharomyces cerevisiae.
J Biol Chem
; 290(40): 24140-51, 2015 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26260787
17.
Demethylmenaquinol is a substrate of Escherichia coli nitrate reductase A (NarGHI) and forms a stable semiquinone intermediate at the NarGHI quinol oxidation site.
Biochim Biophys Acta
; 1847(8): 739-47, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25976528
18.
Biosynthesis and physiology of coenzyme Q in bacteria.
Biochim Biophys Acta
; 1837(7): 1004-11, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24480387
19.
Effect of vanillic acid on COQ6 mutants identified in patients with coenzyme Q10 deficiency.
Biochim Biophys Acta
; 1842(1): 1-6, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24140869
20.
Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrins.
Biochem J
; 460(1): 79-89, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24624902