Detalhe da pesquisa
1.
Determination of in vitro hepatotoxic potencies of a series of perfluoroalkyl substances (PFASs) based on gene expression changes in HepaRG liver cells.
Arch Toxicol
; 97(4): 1113-1131, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36864359
2.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Arch Toxicol
; 96(12): 3407-3419, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36063173
3.
Applicability of generic PBK modelling in chemical hazard assessment: A case study with IndusChemFate.
Regul Toxicol Pharmacol
; 136: 105267, 2022 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-36367522
4.
Applicability of organ-on-chip systems in toxicology and pharmacology.
Crit Rev Toxicol
; 51(6): 540-554, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34463591
5.
Systemic PFOS and PFOA exposure and disturbed lipid homeostasis in humans: what do we know and what not?
Crit Rev Toxicol
; 51(2): 141-164, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33853480
6.
Occupational exposure to hexavalent chromium. Part II. Hazard assessment of carcinogenic effects.
Regul Toxicol Pharmacol
; 126: 105045, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34506880
7.
Occupational exposure to hexavalent chromium. Part I. Hazard assessment of non-cancer health effects.
Regul Toxicol Pharmacol
; 126: 105048, 2021 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-34563613
8.
Oxygen tension influences embryonic stem cell maintenance and has lineage specific effects on neural and cardiac differentiation.
Differentiation
; 115: 1-10, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738735
9.
An update on the hazard of and exposure to diethyl hexyl phthalate (DEHP) alternatives used in medical devices.
Crit Rev Toxicol
; 50(8): 650-672, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33006299
10.
Culture Conditions Affect Chemical-Induced Developmental Toxicity In Vitro: The Case of Folic Acid, Methionine and Methotrexate in the Neural Embryonic Stem Cell Test.
Altern Lab Anim
; 48(4): 173-183, 2020 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33034509
11.
Testing developmental toxicity in a second species: are the differences due to species or replication error?
Regul Toxicol Pharmacol
; 107: 104410, 2019 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-31226390
12.
Why Do Countries Regulate Environmental Health Risks Differently? A Theoretical Perspective.
Risk Anal
; 39(2): 439-461, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30110518
13.
Design and validation of an ontology-driven animal-free testing strategy for developmental neurotoxicity testing.
Toxicol Appl Pharmacol
; 354: 136-152, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29544899
14.
Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.
Toxicol Appl Pharmacol
; 354: 3-6, 2018 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29447839
15.
In vitro to in vivo extrapolation of effective dosimetry in developmental toxicity testing: Application of a generic PBK modelling approach.
Toxicol Appl Pharmacol
; 332: 109-120, 2017 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28760446
16.
Embryotoxic and pharmacologic potency ranking of six azoles in the rat whole embryo culture by morphological and transcriptomic analysis.
Toxicol Appl Pharmacol
; 322: 15-26, 2017 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28263823
17.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Crit Rev Toxicol
; 47(5): 402-414, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-27766926
18.
Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement.
Arch Toxicol
; 91(2): 1001-1006, 2017 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-27714423
19.
Applying 'omics technologies in chemicals risk assessment: Report of an ECETOC workshop.
Regul Toxicol Pharmacol
; 91 Suppl 1: S3-S13, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28958911
20.
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Crit Rev Toxicol
; 46(10): 900-910, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27848393