Small Female Occupant Response in Reclined and Upright Seated Postures in Frontal Impacts.

The objective of this study was to compare the kinematics of the head-neck, torso, pelvis, and lower extremities and document injuries and their patterns to small female occupants in frontal impacts with upright and reclined postures using an experimental model. Six postmortem human surrogates (PMHS) with a mean stature of 154 ± 9.0 cm and mass of 49 ± 12 kg were equally divided between upright and reclined groups (seatback: 25 deg and 45 deg), restrained by a three-point integrated belt, positioned on a semirigid seat, and exposed to low and moderate crash velocities (15 km/h and 32 km/h respectively). The response between the upright and reclined postures was similar in magnitude and curve morphology. While none of the differences were statistically significant, the thoracic spine demonstrated increased downward (+Z) displacement, and the head demonstrated an increased horizontal (+X) displacement for the reclined occupants. In contrast, the upright occupants showed a slightly increased downward (+Z) displacement at the head, but the torso displaced primarily along the +X direction. The posture angles between the two groups were similar at the pelvis and different at the thorax and head. At 32 km/h, both cohorts exhibited multiple rib failure, with upright specimens having a greater number of severe fractures. Although MAIS was the same in both groups, the upright specimens had more bi-cortical rib fractures, suggesting the potential for pneumothorax. This preliminary study may be useful in validating physical (ATDs) and computational (HBMs) surrogates.

Three-Dimensional-Digital Image Correlation Methodology for Kinematic Measurements of Non-Penetrating Blunt Impacts.

Blunt force trauma remains a serious threat to many populations and is commonly seen in motor vehicle crashes, sports, and military environments. Effective design of helmets and protective armor should consider biomechanical tolerances of organs in which they intend to protect and require accurate measurements of deformation as a primary injury metric during impact. To overcome challenges found in velocity and displacement measurements during blunt impact using an integrated accelerometer and two-dimensional (2D) high-speed video, three-dimensional (3D) digital image correlation (DIC) measurements were taken and compared to the accepted techniques. A semispherical impactor was launched at impact velocities from 14 to 20 m/s into synthetic ballistic gelatin to simulate blunt impacts observed in behind armor blunt trauma (BABT), falls, and sports impacts. Repeated measures Analysis of Variance resulted in no significant differences in maximum displacement (p = 0.10), time of maximum displacement (p = 0.21), impact velocity (p = 0.13), and rebound velocity (p = 0.21) between methods. The 3D-DIC measurements demonstrated equal or improved percent difference and low root-mean-square deviation compared to the accepted measurement techniques. Therefore, 3D-DIC may be utilized in BABT and other blunt impact applications for accurate 3D kinematic measurements, especially when an accelerometer or 2D lateral camera analysis is impractical or susceptible to error.

Occupant Injury and Response on Oblique-Facing Aircraft Seats: A Computational Study.

Increased interest in the airline industry to enhance occupant comfort and maximize seating density has prompted the design and installation of obliquely mounted seats in aircraft. Previous oblique whole-body sled tests demonstrated multiple failures, chiefly distraction-associated spinal injuries under oblique impacts. The present computational study was performed with the rationale to examine how oblique loading induces component level responses and associated injury occurrence. The age-specific human body model (HBM) was simulated for two oblique seating conditions (with and without an armrest). The boundary conditions consisted of a 16 g standard aviation crash pulse, 45 deg seat orientation, and with restrained pelvis and lower extremities. The overall biofidelity rating for both conditions ranged from 0.5 to 0.7. The validated models were then used to investigate the influence of pulse intensity and seat orientation by varying the pulse from 16 g to 8 g and seat orientation from 0 deg to 90 deg. A total of 12 parametric simulations were performed. The pulse intensity simulations suggest that the HBM could tolerate 11.2 g without lumbar spine failure, while the possibility of cervical spine failure reduced with the pulse magnitude <9.6 g pulse. The seat orientation study demonstrated that for all seat angles the HBM predicted failure in the cervical and lumbar regions at 16 g; however, the contribution of the tensile load and lateral and flexion moments varied with respect to the change in seat angle. These preliminary outcomes are anticipated to assist in formulating safety standards and in designing countermeasures for oblique seating configurations.

Surface wave analysis of the skin for penetrating and non-penetrating projectile impact in porcine legs.

Secondary blast injuries may result from high-velocity projectile fragments which ultimately increase medical costs, reduce active work time, and decrease quality of life. The role of skin penetration requires more investigation in energy absorption and surface mechanics for implementation in computational ballistic models. High-speed ballistic penetration studies have not considered penetrating and non-penetrating biomechanical properties of the skin, including radial wave displacement, resultant surface wave speed, or projectile material influence. A helium-pressurized launcher was used to accelerate 3/8″ (9.525 mm) diameter spherical projectiles toward seventeen whole porcine legs from seven pigs (39.53 ± 7.28 kg) at projectile velocities below and above V50. Projectiles included a mix of materials: stainless steel (n = 26), Si3N4 (n = 24), and acetal plastic (n = 24). Tracker video analysis software was used to determine projectile velocity at impact from the perpendicular view and motion of the tissue displacement wave from the in-line view. Average radial wave displacement and surface wave speed were calculated for each projectile material and categorized by penetrating or non-penetrating impacts. Two-sample t-tests determined that non-penetrating projectiles resulted in significantly faster surface wave speeds in porcine skin for stainless steel (p = 0.002), plastic (p = 0.004), and Si3N4 ball bearings (p = 0.014), while ANOVA determined significant differences in radial wave displacement and surface wave speed between projectile materials. Surface wave speed was used to quantify mechanical properties of the skin including elastic modulus, shear modulus, and bulk modulus during ballistic impact, which may be implemented to simulate accurate deformation behavior in computational impact models.

Male and Female Cervical Spine Biomechanics and Anatomy: Implication for Scaling Injury Criteria.

There is an increased need to develop female-specific injury criteria and anthropomorphic test devices (dummies) for military and automotive environments, especially as women take occupational roles traditionally reserved for men. Although some exhaustive reviews on the biomechanics and injuries of the human spine have appeared in clinical and bioengineering literatures, focus has been largely ignored on the difference between male and female cervical spine responses and characteristics. Current neck injury criteria for automotive dummies for assessing crashworthiness and occupant safety are obtained from animal and human cadaver experiments, computational modeling, and human volunteer studies. They are also used in the military. Since the average human female spines are smaller than average male spines, metrics specific to the female population may be derived using simple geometric scaling, based on the assumption that male and female spines are geometrically scalable. However, as described in this technical brief, studies have shown that the biomechanical responses between males and females do not obey strict geometric similitude. Anatomical differences in terms of the structural component geometry are also different between the two cervical spines. Postural, physiological, and motion responses under automotive scenarios are also different. This technical brief, focused on such nonuniform differences, underscores the need to conduct female spine-specific evaluations/experiments to derive injury criteria for this important group of the population.

Cervical spine injuries, mechanisms, stability and AIS scores from vertical loading applied to military environments.

PURPOSE: The purpose of this study was to determine injuries to osteo-ligamentous structures of cervical column, mechanisms, forces, severities and AIS scores from vertical accelerative loading. METHODS: Seven human cadaver head-neck complexes (56.9 ± 9.5 years) were aligned based on seated the posture of military soldiers. Army combat helmets were used. Specimens were attached to a vertical accelerator to apply caudo-cephalad g-forces. They were accelerated with increasing insults. Intermittent palpation and radiography were done. A roof structure mimicking military vehicle interior was introduced after a series of tests and experiments were conducted following similar protocols. Upon injury detection, CT and dissection were done. Temporal force responses were extracted, peak forces and times of occurrence were obtained, injury severities were graded, and spine stability was determined. RESULTS: Injuries occurred in tests only when the roof structure was included. Responses were tri-phasic: initial thrust, secondary tensile, tertiary roof contact phases. Peak forces: 1364-4382 N, initial thrust, 165-169 N, secondary tensile, 868-3368 N tertiary helmet-head roof contact phases. Times of attainments: 5.3-9.6, 31.7-42.6, 55.0-70.8 ms. Injuries included fractures and joint disruptions. Multiple injuries occurred in all but one specimen. A majority of injury severities were AIS = 2. Spines were considered unstable in a majority of cases. CONCLUSIONS: Spine response was tri-phasic. Injuries occurred in roof contact tests with the helmeted head-neck specimen. Multiplicity and unstable nature of AIS = 2 level injuries, albeit at lower severities, might predispose the spine to long-term accelerated degenerative changes. Clinical protocols should include a careful evaluation of sub-catastrophic injuries in military patients.

Deflection corridors of abdomen and thorax in oblique side impacts using equal stress equal velocity approach: comparison with other normalization methods.

The first objective of the study was to determine the thorax and abdomen deflection time corridors using the equal stress equal velocity approach from oblique side impact sled tests with postmortem human surrogates fitted with chestbands. The second purpose of the study was to generate deflection time corridors using impulse momentum methods and determine which of these methods best suits the data. An anthropometry-specific load wall was used. Individual surrogate responses were normalized to standard midsize male anthropometry. Corridors from the equal stress equal velocity approach were very similar to those from impulse momentum methods, thus either method can be used for this data. Present mean and plus/minus one standard deviation abdomen and thorax deflection time corridors can be used to evaluate dummies and validate complex human body finite element models.

Effect of muscle activation scheme in human head-neck model on estimating cervical spine ligament strain from military volunteer frontal impact data.

Cervical spine (c-spine) injuries are a common injury during automobile crashes. The objective of this study is to verify an existing head-neck (HN) finite element model with military volunteer frontal impact kinematics by varying the muscle activation scheme from previous literature. Proper muscle activation will allow for accurate percent elongation (strain) of the c-spine ligaments and will serve to establish ligamentous response during non-injury frontal impacts. Previous human research volunteer (HRV) frontal impact sled tests reported kinematic data that served as the input for HN model simulation. Peak sled acceleration (PSA) was varied between 10G and 30G for HRVs. Muscle activation was shifted to begin at 0 ms at start of impact to allow for proper muscle contraction in the HN model. Then, extensor muscle activation magnitude was varied between 20 and 100% to determine the proper activation necessary to match kinematic outputs from the model with experimental results. The model was validated against 10G test recorded response. Ligament strain was measured from multiple ligaments along the c-spine once the model was verified. The 40% activated extensor muscle scheme was deemed the most biofidelic, with CORA scores of 0.743 and 0.686 for head X linear acceleration and angular Y acceleration for 10G pulse. All PSA groups scored well with this muscle activation. Most ligaments were buffered well by the active simulation, with only the interspinous ligament nearing physiologic injury. With the HN model verified against additional kinematic data, simulations with higher accelerations to predict areas of injury in real life crash scenarios are possible.

Comparison of Axial Force Attenuation Characteristics in Two Different Lower Extremity Anthropomorphic Test Devices.

INTRODUCTION: Any type of boot or footwear is designed to attenuate and distribute loading to the bottom of the foot. Anthropomorphic test device (ATDs) are used to assess potential countermeasures against these loads. The specific aims of this study were to compare and quantify force attenuation characteristics as a function of input energy for Hybrid-III and Mil-Lx ATD human surrogates. MATERIALS AND METHODS: Two lower leg ATD surrogates (Mil-Lx and Hybrid-III) were tested to investigate the influence of a commercially available military boot on lower extremity force response and assess such differences against previously published postmortem human surrogate studies. The testing apparatus impacted the bottom of the foot using a rigid plate at velocities from 2 to 10 m/s. Tests were conducted on each ATD to obtain axial force response with and without boots as a function of input energy. RESULTS: Peak forces ranged from 1 to 16.4 kN for the Hybrid-III, and 1 to 8.4 kN for the Mil-Lx for similar input conditions. The average force attenuation for the Hybrid-III at upper and lower load cells was 71% (59%-80%) and 70% (58%-78%). The average attenuation for the Mil-Lx at upper and lower load cells was 20% (13%-28%) and 37% (36%-37%), respectively. At the knee load cell, the attenuated peak loads ranged from 62% to 81% for the Hybrid-III and 16% to 30% for the Mil-Lx. CONCLUSIONS: Force attenuation characteristics in the booted vs unbooted configuration of the Mil-Lx were significantly different than force attenuation characteristics of the H3 and may better represent in vivo forces during vertical impact injuries, such as IED blasts. Hence for military relevant applications where boots are used, the Mil-Lx may provide a more conservative evaluation of lower extremity protection systems.

Cervical spine degeneration specific segmental angular rotational and displacements: A quantitative study.

BACKGROUND: The objective of the present isolated spine study was to evaluate the kinematic differences between groups of normal and degenerated cervical spine specimens. Previous studies on cervical spine degeneration support the existence of the unstable phase during the degeneration process; however, there is a lack of quantitative data available to fully characterize this early stage of degeneration. METHOD: For this effort five degenerated and eight normal cervical spines (C2-T1) were isolated and were subject to pure bending moments of flexion, extension, axial rotation and lateral bending. The specimen quality was assessed based on the grading scale. In the present study, the degeneration was at the C5-C6 level. A four-camera motion analysis system was used to measure the overall primary and segmental motions. FINDING: In the extension mode, the degenerated group demonstrated a significant larger angular rotation as well as antero-posterior displacement at the degenerated level (C5-C6). In contrast, in flexion mode, the degenerated group measured a drastic decrease in angular rotation, at the adjacent level (C6-C7). In other modes of loading as well as in other segmental levels, the degenerated group had similar segmental motion as the normal group. INTERPRETATION: These preliminary results provide single level degeneration specific cervical spine kinematics. The finding demonstrates the influence of degeneration on the kinematics of the normal sub adjacent segment. The degenerated group observed larger translation displacement in the extension mode, which would potentially be a critical parameter in assisting early detection of cervical spine spondylosis with just a functional X-ray scan.

Repeated measures analysis of projectile penetration in porcine legs as a function of storage condition.

Buried blast explosions create small projectiles which can become lodged in the tissue of personnel as far away as hundreds of meters. Without appropriate treatment, these lodged projectiles can become a source of infection and prolonged injury to soldiers in modern combat. Human cadavers can be used as surrogates for living humans for ballistic penetration testing, but human cadavers are frozen during transport and storage. The process of freezing and thawing the tissue before testing may change the biomechanical properties of the tissue. The goal of the current study was to understand penetration threshold differences between fresh, refrigerated, and frozen tissue and investigate factors that may contribute to these differences. A custom-built pneumatic launcher was used to accelerate 3/16″ stainless steel ball bearings toward porcine legs that were either tested fresh, following refrigerated storage, or following frozen storage. A generalized linear mixed model, accounting for within-animal dependence, owing to repeated observations, was found to be the most appropriate for these data and was used for analysis. The "generalized" model accommodated non-continuous observations, provided a straight-forward way to implement the repeated measures, and provided a risk estimate for projectile penetration. Both storage condition (p = 0.48) and leg (p = 0.07) were shown to be not significant and the confidence intervals for those variables were overlapping. As all covariates were found to be non-significant, a single model containing all impacts was used to develop a V50, or velocity at which 50% of impacts are expected to penetrate. From this model, 50% probability of penetration occurs at 137.3 m/s with 95% confidence intervals at 132.0 and 144.0 m/s. In this study, the fresh legs and previously frozen legs allowed penetration at similar velocities indicating that previously frozen legs were acceptable surrogates for fresh legs. This study only compared the penetration threshold in tissues that had been stored in differing conditions. To truly study penetration, more conditions will need to be studied including the effects of projectile mass and material, the effects of projectile shape, and the effects of clothing or protective layers on penetration threshold.

Calcaneus fracture pattern and severity: Role of local trabecular bone density.

Calcaneus fracture is the most common tarsal bone fracture and is associated with external loads resulting from vehicle crashes, under body blasts, or sports. Almost 50% of weight bearing by the foot occurs through the calcaneus and its surgical fixation remains a challenging procedure. Postmortem human subjects were used to measure the regional trabecular BMD of the calcaneus. Mean age, height and weight of the included 14 specimens was 69 years, 177 cm and 80 kg respectively. Using a custom mode within Quantitative Computed Tomography clinical software; calcaneal trabecular BMD in the anterior and posterior regions was quantified. Tolerance data and calcaneus fracture patterns were also available for these specimens from previous tests. The posterior region of the calcaneus had a higher mean BMD (114 mg/cc) than the anterior region (81 mg/cc). These BMD differences also paralleled injury outcome of specimens from axial loading with 50% of specimens resulting in high severity anterior region calcaneal fractures and 36% of specimens resulting in low severity posterior calcaneal fractures. These findings may be reflective of the lower BMD in the anterior region, although the load was uniformly distributed across the plantar surface of the foot. Severity of fracture was greater (intraarticular/crush) in the anterior region as compared to fractures of the posterior region. The BMD ratio between anterior and posterior was significant (p = 0.02) between anterior region fractures and posterior region fractures. The ratio parameter may indicate that the disparity in trabecular BMD between anterior and posterior calcaneus regions is more important in predicting injury outcome than the absolute BMD value of each region.

Obese Occupant Response in Reclined and Upright Seated Postures in Frontal Impacts.

The American population is getting heavier and automated vehicles will accommodate unconventional postures. While studies replicating mid-size and upright fore-aft seated occupants are numerous, experiments with post-mortem human subjects (PMHS) with obese and reclined occupants are sparse. The objective of this study was to compare the kinematics of the head-neck, torso and pelvis, and document injuries and injury patterns in frontal impacts. Six PMHS with a mean body mass index of 38.2 ± 5.3 kg/m2 were equally divided between upright and reclined groups (seatback: 23°, 45°), restrained by a three-point integrated belt, positioned on a semi-rigid seat, and exposed to low and moderate velocities (15, 32 km/h). Data included belt loads, spinal accelerations, kinematics, and injuries from x-rays, computed tomography, and necropsy. At 15 km/h speed, no significant difference in the occupant kinematics and evidence of orthopedic failure was observed. At 32 km/h speed, the primary difference between the cohorts was significantly larger Z displacements in the reclined occupant at the head (190 ± 32 mm, vs. 105 ± 33 mm p < 0.05) and femur (52 ± 18 mm vs. 30 ± 10 mm, p < 0.05). All the moderate-speed tests produced at least one thorax injury. Rib fractures were scattered around the circumference of the rib-cage in the upright, while they were primarily concentrated on the anterior aspect of the rib-cage in two reclined specimens. Although MAIS was the same in both groups, the reclined specimens had more bi-cortical rib fractures, suggesting the potential for pneumothorax. While not statistical, these results suggest enhanced injuries with reclined obese occupants. These results could serve as a data set for validating the response of restrained obese anthropometric test device (ATDs) and computational human body models.

A new PMHS model for lumbar spine injuries during vertical acceleration.

Ejection from military aircraft exerts substantial loads on the lumbar spine. Fractures remain common, although the overall survivability of the event has considerably increased over recent decades. The present study was performed to develop and validate a biomechanically accurate experimental model for the high vertical acceleration loading to the lumbar spine that occurs during the catapult phase of aircraft ejection. The model consisted of a vertical drop tower with two horizontal platforms attached to a monorail using low friction linear bearings. A total of four human cadaveric spine specimens (T12-L5) were tested. Each lumbar column was attached to the lower platform through a load cell. Weights were added to the upper platform to match the thorax, head-neck, and upper extremity mass of a 50th percentile male. Both platforms were raised to the drop height and released in unison. Deceleration characteristics of the lower platform were modulated by foam at the bottom of the drop tower. The upper platform applied compressive inertial loads to the top of the specimen during deceleration. All specimens demonstrated complex bending during ejection simulations, with the pattern dependent upon the anterior-posterior location of load application. The model demonstrated adequate inter-specimen kinematic repeatability on a spinal level-by-level basis under different subfailure loading scenarios. One specimen was then exposed to additional tests of increasing acceleration to induce identifiable injury and validate the model as an injury-producing system. Multiple noncontiguous vertebral fractures were obtained at an acceleration of 21 g with 488 g/s rate of onset. This clinically relevant trauma consisted of burst fracture at L1 and wedge fracture at L4. Compression of the vertebral body approached 60% during the failure test, with -6,106 N axial force and 168 Nm flexion moment. Future applications of this model include developing a better understanding of the vertebral injury mechanism during pilot ejection and developing tolerance limits for injuries sustained under a variety of different vertical acceleration scenarios.

Use of postmortem human subjects to describe injury responses and tolerances.

Traumatic injuries from blunt, penetrating, and blast events expose the human body to unintentional and intentional external mechanical loads. To mitigate trauma and develop safety-engineered devices for clinical and bioengineering applications, it is critical to delineate the structural load-bearing anatomy and biomechanics of the various components of the human body. This article presents advances made in the understanding of the injury responses and tolerances through experiments conducted using intact or segmented tissues from postmortem human subjects (PMHS), and a considerable majority of data for the presentation has been extracted from studies conducted at the Institutions of the authors. The role of the PMHS model for studying traumatic injuries to the head and face, vertebral column (cervical, thoracic and lumbar spines), thorax, abdomen, pelvis, and lower extremities is discussed. Different impact loading scenarios, likely responsible for the initial trauma causation, are considered in the analysis and determination of the human response to injury. Clinical advances made using the PMHS model are discussed. This includes vertebral stabilization system evaluations secondary to traumatic injuries to the spinal column. The critical importance of using data from the PMHS model in developing validated computational models for advancing crashworthiness research, occupant safety in motor vehicle crashes, medical devices, and safety-engineering applications is highlighted.

The relationship between lower neck shear force and facet joint kinematics during automotive rear impacts.

A primary goal of biomechanical safety research is the definition of localized injury thresholds in terms of quantities that are repeatable and easily measureable during experimentation. Recent biomechanical experimentation using human cadavers has highlighted the role of lower cervical facet joints in the injury mechanism resulting from low-speed automotive rear impacts. The present study was conducted to correlate lower neck forces and moments with facet joint motions during simulated rear impacts in an effort to define facet joint injury tolerance thresholds that can be used to assess automobile safety. Four male and four female intact head-neck complexes were obtained from cadaveric specimens and subjected to simulated automotive rear impacts using a pendulum-minisled device. Cervical spine segmental angulations and localized facet joint kinematics were correlated to shear and axial forces, and bending moments at the cervico-thoracic junction using linear regression. R(2) coefficients indicated that spinal kinematics correlated well with lower neck shear force and bending moment. Correlation slope was steeper in female specimens, indicating greater facet joint motions for a given loading magnitude. This study demonstrated that lower neck loads can be used to predict lower cervical facet joint kinematics during automotive rear impacts. Higher correlation slope in female specimens corresponds to higher injury susceptibility in that population. Although lower neck shear force and bending moment demonstrated adequate correlation with lower cervical facet joint motions, shear force is likely the better predictor due to similarity in the timing of peak magnitudes with regard to maximum facet joint motions.

Pelvic Injury Risk Curves for the Military Populations From Lateral Impact.

INTRODUCTION: Current methods for transporting military troops include nonstandard seating orientations, which may result in novel injuries because of different types/directions of loading impact. The objective of this study is to develop pelvic injury risk curves (IRCs) under lateral impacts from human cadaver tests using survival analysis for application to military populations. METHODS: Published data from lateral impacts applied to whole-body cadaver specimens were analyzed. Forces were treated as response variables. Demographics and body mass index (BMI) were covariates. Injury risk curves were developed for forces without covariates, for males, females, 83 kg body mass, and 25 kg/m2 BMI. Mean and ± 95% confidence interval IRCs, normalized confidence interval sizes at discrete risk levels, and quality indices were obtained for each metric-covariate combination curve. RESULTS: Mean age, stature, total body mass, and BMI were 70.1 ± 8.6 years, 1.67 ± 0.1 m, 67.0 ± 14.4 kg, and 23.9 ± 3.97 kg/m2, respectively. For a total body mass of 83 kg, peak forces at 10%, 25%, and 50% probability levels were 5.7 kN, 7.4 kN, and 9.6 kN, respectively. For males, peak forces at the 10%, 25%, and 50% probability levels were 4.8 kN, 6.4 kN, and 8.4 kN, respectively. For females, peak forces at the 10%, 25%, and 50% probability levels were 3.0 kN, 4.0 kN, and 5.2 kN, respectively. Other data and risk curves are given. CONCLUSIONS: The IRCs developed in this study can be used as injury criteria for the crashworthiness of future generation military vehicles. The introduction of BMI, sex, and total body mass as covariates quantified their contributions. These IRCs can be used with finite element models to assess and predict injury in impact environments to advance Soldier safety. Manikins specific to relevant military anthropometry may be designed and/or evaluated with the present IRCs to assess and mitigate musculoskeletal injuries associated with this posture and impact direction.

An Improved Method for Developing Injury Risk Curves Using the Brier Metric Score.

Many injury metrics are routinely proposed from measured or derived quantities from biomechanical experiments using post mortem human subjects (PMHS). The existing literature did not provide guidance on deciding between parameters collected in an experiment that would be best to use for the development of human injury probability curves (HIPC). The objective of this study was to use the Brier Metric Score (BMS) to identify the most appropriate metric from an experiment that predicts injury outcomes. The Brier Metric Score assesses how well a metric predicts the outcome for a censored data point (a lower BMS is better). Survival analysis was then conducted with the selected metric and the best distribution was selected using Akaike information criterion (AIC). Confidence intervals (CIs) and the normalized confidence interval width (NCIS) were calculated for the injury probability curve. The testing and validation of the methods described were performed using biomechanics data in the open literature. The methods for the HIPC development procedure detailed herein have been rigorously tested and used in the generation of WIAMan HIPCs and Injury Assessment Reference Curves (IARCs) for the WIAMan ATD, but can also be used in other ATD or PMHS injury risk curve development.

Time and temperature sensitivity of the hybrid III lumbar spine.

OBJECTIVE: Researchers have found a variety of uses for the Hybrid III (HIII) dummy that fall beyond the scope of its original purpose as an automotive crash test dummy. Some of these expanded roles for the HIII introduce situations that were not envisioned in the dummy's original design parameters, such as a relatively rapid succession of tests or outdoor testing scenarios where temperature is not easily controlled. This study investigates how the axial compressive stiffness of the HIII lumbar spine component is affected by the duration of the time interval between tests. Further, it measures the effect of temperature on the compressive stiffness of the lumbar spine through a range of temperatures relevant to indoor and outdoor testing. METHODS: High-rate axial compression tests were run on a 50th percentile male HIII lumbar component in a materials testing machine. To characterize the effects of tests recovery intervals, between-test recovery was varied from 2 hours to 1 minute. To quantify temperature effects, environmental temperature conditions of 12.5°, 25°, and 37.5 °C were tested. RESULTS: During repeated compressive loading, the force levels decreased consistently across long and short rest intervals. Even after 2 hours of rest between tests, full viscoelastic recovery was not observed. Temperature effects were pronounced, resulting in compressive force differences of 261% over the range of 12.5° to 37.5 °C. Compared to the stiffness of the lumbar at 25 °C, the stiffness at 37.5 °C fell by 40%; at 12.5 °C, the stiffness more than doubled, increasing by 115%. CONCLUSIONS: A modest decrease in temperature can be sufficient to dramatically change the response and repeatability of the lumbar HIII component in compressive loading. The large magnitude of the temperature effect has severe implications in its ability to overwhelm the contributions of targeted test variables. These findings highlight the importance of controlling, monitoring and reporting temperature conditions during HIII testing, even in indoor laboratory environments.

Determination of normative neck muscle morphometry using upright MRI with comparison to supine data.

BACKGROUND: Neck muscles are important in the static and dynamic stability of the head-neck complex. Deep neck muscles act to maintain upright posture and superficial muscles are responsible for gross movements. Previous studies have quantified neck muscle geometry using traditional supine magnetic resonance imaging (MRI). However, supine orientation removes the vertical load on the cervical spine from the head-neck complex and changes the relative orientation of the spine and neck muscles. Therefore, the purpose of this study was to demonstrate the feasibility of upright MRI to obtain neck muscle morphometric data on a spinal level-by-level basis for subjects in upright seated positions. METHODS: Upright MRI scans were obtained of the neck region for six younger male volunteers in neutral and flexed positions. Planar images were oriented parallel to the intervertebral disc space at each level. Cross-sectional area (CSA) and orientation of neck muscles were quantified at four spinal levels. RESULTS: Area and position of all four muscles were significantly dependent upon spinal level. Average CSA of the sternocleidomastoid, longus colli, levator scapulae, and trapezius muscles in neutral position were 512, 113, 281, and 174 mm2. Head-neck position significantly affected area and position of the sternocleidomastoid and position of posterior neck muscles. DISCUSSION: Comparison of neck muscle areas from the present study to a previous study incorporating supine MRI demonstrated differing trends between anterior and posterior neck muscles that may be attributable to upright orientation of volunteers and planar image orientation in the present study. Differences between supine and upright MRI identified in the present study may warrant incorporation of this technique in future spinal imaging studies.