Detalhe da pesquisa
1.
Noxa upregulation and 5-gene apoptotic biomarker panel in colorectal cancer.
Eur J Clin Invest
; 51(1): e13353, 2021 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-32682341
2.
IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.
BMC Cancer
; 16: 624, 2016 08 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27520705
3.
Tumor heterogeneity revealed by KRAS, BRAF, and PIK3CA pyrosequencing: KRAS and PIK3CA intratumor mutation profile differences and their therapeutic implications.
Hum Mutat
; 35(3): 329-40, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24352906
4.
Design and Synthesis of Novel 2-Acetamido, 6-Carboxamide Substituted Benzothiazoles as Potential BRAFV600E Inhibitors - In vitro Evaluation of their Antiproliferative Activity.
ChemMedChem
; 18(22): e202300322, 2023 11 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37792577
5.
BRAF and RAS oncogenes regulate Rho GTPase pathways to mediate migration and invasion properties in human colon cancer cells: a comparative study.
Mol Cancer
; 10: 118, 2011 Sep 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-21943101
6.
The expression of ELK transcription factors in adult DRG: Novel isoforms, antisense transcripts and upregulation by nerve damage.
Mol Cell Neurosci
; 44(2): 165-77, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20304071
7.
BRAF paradox breakers PLX8394, PLX7904 are more effective against BRAFV600Ε CRC cells compared with the BRAF inhibitor PLX4720 and shown by detailed pathway analysis.
Biochim Biophys Acta Mol Basis Dis
; 1867(4): 166061, 2021 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33385518
8.
Epithelial-mesenchymal transition in cancer metastasis: mechanisms, markers and strategies to overcome drug resistance in the clinic.
Biochim Biophys Acta
; 1796(2): 75-90, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19306912
9.
Gene expression profile associated with oncogenic ras-induced senescence, cell death, and transforming properties in human cells.
Cancer Invest
; 28(6): 563-87, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19883200
10.
TRAIL receptor upregulation and the implication of KRAS/BRAF mutations in human colon cancer tumors.
Int J Cancer
; 125(9): 2127-35, 2009 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19637313
11.
TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.
Mol Cancer Res
; 6(6): 1071-83, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18567809
12.
Fra-1 regulates vimentin during Ha-RAS-induced epithelial mesenchymal transition in human colon carcinoma cells.
Int J Cancer
; 122(8): 1745-56, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18098284
13.
Culture of primary epithelial adenoma cells from familial adenomatous polyposis patients.
Anticancer Res
; 28(2A): 843-6, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18507027
14.
Quercetin enhances TRAIL-mediated apoptosis in colon cancer cells by inducing the accumulation of death receptors in lipid rafts.
Mol Cancer Ther
; 6(9): 2591-9, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17876056
15.
Death receptor 5 (DR5) and a 5-gene apoptotic biomarker panel with significant differential diagnostic potential in colorectal cancer.
Sci Rep
; 6: 36532, 2016 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27827395
16.
BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells.
Oncotarget
; 7(8): 9188-221, 2016 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26802026
17.
EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene.
PLoS One
; 9(12): e115276, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25549357
18.
BRAF vs RAS oncogenes: are mutations of the same pathway equal? Differential signalling and therapeutic implications.
Oncotarget
; 5(23): 11752-77, 2014 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25361007
19.
Epigenetic regulation of miR-21 in colorectal cancer: ITGB4 as a novel miR-21 target and a three-gene network (miR-21-ITGΒ4-PDCD4) as predictor of metastatic tumor potential.
Epigenetics
; 9(1): 129-41, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24149370
20.
The TRAIL of oncogenes to apoptosis.
Biofactors
; 39(4): 343-54, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23813857