Detalhe da pesquisa
1.
Overcoming doxorubicin resistance in triple-negative breast cancer using the class I-targeting HDAC inhibitor bocodepsin/OKI-179 to promote apoptosis.
Breast Cancer Res
; 26(1): 35, 2024 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38429789
2.
ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer.
BMC Cancer
; 22(1): 1107, 2022 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36309653
3.
Bitter melon juice intake with gemcitabine intervention circumvents resistance to gemcitabine in pancreatic patient-derived xenograft tumors.
Mol Carcinog
; 59(10): 1227-1240, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32816368
4.
RX-5902, a novel ß-catenin modulator, potentiates the efficacy of immune checkpoint inhibitors in preclinical models of triple-negative breast Cancer.
BMC Cancer
; 20(1): 1063, 2020 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33148223
5.
A phase II clinical trial of the Aurora and angiogenic kinase inhibitor ENMD-2076 for previously treated, advanced, or metastatic triple-negative breast cancer.
Breast Cancer Res
; 20(1): 82, 2018 08 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30071865
6.
A Phase I Dose-Escalation Study of Linsitinib (OSI-906), a Small-Molecule Dual Insulin-Like Growth Factor-1 Receptor/Insulin Receptor Kinase Inhibitor, in Combination with Irinotecan in Patients with Advanced Cancer.
Oncologist
; 23(12): 1409-e140, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30139840
7.
Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.
BMC Cancer
; 18(1): 136, 2018 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29402316
8.
Dual compartmental targeting of cell cycle and angiogenic kinases in colorectal cancer models.
Anticancer Drugs
; 29(9): 827-838, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30048249
9.
Ephrin-B2 overexpression predicts for poor prognosis and response to therapy in solid tumors.
Mol Carcinog
; 56(3): 1189-1196, 2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27649287
10.
Targeting the protein ubiquitination machinery in melanoma by the NEDD8-activating enzyme inhibitor pevonedistat (MLN4924).
Invest New Drugs
; 35(1): 11-25, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27783255
11.
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer.
Int J Cancer
; 138(1): 195-205, 2016 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26152787
12.
Phase I trial of vandetanib in combination with gemcitabine and capecitabine in patients with advanced solid tumors with an expanded cohort in pancreatic and biliary cancers.
Invest New Drugs
; 34(2): 176-83, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26715573
13.
An integrated bioinformatics analysis to dissect kinase dependency in triple negative breast cancer.
BMC Genomics
; 16 Suppl 12: S2, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26681397
14.
Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.
Int J Cancer
; 136(8): 1967-75, 2015 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25242168
15.
Numerical modeling considerations for an applied nonlinear Schrödinger equation.
Appl Opt
; 54(6): 1426-35, 2015 Feb 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25968209
16.
Population-level comparisons of gene regulatory networks modeled on high-throughput single-cell transcriptomics data.
Nat Comput Sci
; 4(3): 237-250, 2024 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-38438786
17.
Examination of Wnt signaling as a therapeutic target for pancreatic ductal adenocarcinoma (PDAC) using a pancreatic tumor organoid library (PTOL).
PLoS One
; 19(4): e0298808, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38598488
18.
A Phase Ib Expansion Cohort Evaluating Aurora A Kinase Inhibitor Alisertib and Dual TORC1/2 Inhibitor Sapanisertib in Patients with Advanced Solid Tumors.
Cancers (Basel)
; 16(8)2024 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38672538
19.
Pancreatic Ductal Adenocarcinoma Cells Regulate NLRP3 Activation to Generate a Tolerogenic Microenvironment.
Cancer Res Commun
; 3(9): 1899-1911, 2023 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37772994
20.
Testing Cancer Immunotherapeutics in a Humanized Mouse Model Bearing Human Tumors.
J Vis Exp
; (190)2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36591990