Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Trial of Three Rounds of Mass Azithromycin Administration for Yaws Eradication.

John, Lucy N; Beiras, Camila G; Houinei, Wendy; Medappa, Monica; Sabok, Maria; Kolmau, Reman; Jonathan, Eunice; Maika, Edward; Wangi, James K; Pospísilová, Petra; Smajs, David; Ouchi, Dan; Galván-Femenía, Iván; Beale, Mathew A; Giacani, Lorenzo; Clotet, Bonaventura; Mooring, Eric Q; Marks, Michael; Vall-Mayans, Martí; Mitjà, Oriol.

N Engl J Med ; 386(1): 47-56, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34986286

2.

Analysis of Treponema pallidum Strains From China Using Improved Methods for Whole-Genome Sequencing From Primary Syphilis Chancres.

Chen, Wentao; Smajs, David; Hu, Yongfei; Ke, Wujian; Pospísilová, Petra; Hawley, Kelly L; Caimano, Melissa J; Radolf, Justin D; Sena, Arlene; Tucker, Joseph D; Yang, Bin; Juliano, Jonathan J; Zheng, Heping; Parr, Jonathan B.

J Infect Dis ; 223(5): 848-853, 2021 03 03.

Artigo em Inglês | MEDLINE | ID: mdl-32710788

3.

The Arg753Gln Polymorphism of Toll-Like Receptor 2 Has a Lower Occurrence in Patients with Syphilis, Suggesting Its Protective Effect in Czech and Slovak Individuals.

Grillová, Linda; Musilová, Jana; Janecková, Klára; Pospísilová, Petra; Kuklová, Ivana; Woznicová, Vladana; Zákoucká, Hana; Smajs, David.

Infect Immun ; 89(1)2020 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-33077622

4.

Macrolide resistance in yaws.

Smajs, David; Pospísilová, Petra.

Lancet ; 391(10130): 1555-1556, 2018 04 21.

Artigo em Inglês | MEDLINE | ID: mdl-29428184

5.

Syphilis-causing strains belong to separate SS14-like or Nichols-like groups as defined by multilocus analysis of 19 Treponema pallidum strains.

Nechvátal, Lukás; Petrosová, Helena; Grillová, Linda; Pospísilová, Petra; Mikalová, Lenka; Strnadel, Radim; Kuklová, Ivana; Kojanová, Martina; Kreidlová, Miluse; Vanousová, Daniela; Procházka, Premysl; Zákoucká, Hana; Krchnáková, Alena; Smajs, David.

Int J Med Microbiol ; 304(5-6): 645-53, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24841252

6.

Coinfection of a Yaws Patient with Two Closely Related Treponema pallidum subsp. pertenue Strains: a rare event with potential evolutionary implications.

Medappa, Monica; Pospísilová, Petra; John, Lucy N; González-Beiras, Camila; Mitjà, Oriol; Smajs, David.

Acta Trop ; : 107254, 2024 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-38759832

7.

Low genetic diversity of Treponema pallidum ssp. pertenue (TPE) isolated from patients' ulcers in Namatanai District of Papua New Guinea: Local human population is infected by three TPE genotypes.

Medappa, Monica; Pospísilová, Petra; Madruga, Maria Paula M; John, Lucy N; Beiras, Camila G; Grillová, Linda; Oppelt, Jan; Banerjee, Arka; Vall-Mayans, Marti; Mitjà, Oriol; Smajs, David.

PLoS Negl Trop Dis ; 18(1): e0011831, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38166151

8.

Comparison of CDC and sequence-based molecular typing of syphilis treponemes: tpr and arp loci are variable in multiple samples from the same patient.

Mikalová, Lenka; Pospísilová, Petra; Woznicová, Vladana; Kuklová, Ivana; Zákoucká, Hana; Smajs, David.

BMC Microbiol ; 13: 178, 2013 Jul 30.

Artigo em Inglês | MEDLINE | ID: mdl-23898829

9.

Clinical and genomic diversity of Treponema pallidum subsp. pallidum: A global, multi-center study of early syphilis to inform vaccine research.

Seña, Arlene C; Matoga, Mitch M; Yang, Ligang; Lopez-Medina, Eduardo; Aghakanian, Farhang; Chen, Jane S; Bettin, Everton B; Caimano, Melissa J; Chen, Wentao; Garcia-Luna, Jonny A; Hennelly, Christopher M; Jiang, Yinbo; Juliano, Jonathan J; Pospísilová, Petra; Ramirez, Lady; Smajs, David; Tucker, Joseph D; Cely, Fabio Vargas; Zheng, Heping; Hoffman, Irving F; Yang, Bin; Moody, M Anthony; Hawley, Kelly L; Salazar, Juan C; Radolf, Justin D; Parr, Jonathan B.

medRxiv ; 2023 Jul 24.

Artigo em Inglês | MEDLINE | ID: mdl-37546832

10.

Sequencing-based molecular typing of treponema pallidum strains in the Czech Republic: all identified genotypes are related to the sequence of the SS14 strain.

Flasarová, Magdalena; Pospísilová, Petra; Mikalová, Lenka; Valisová, Zuzana; Dastychová, Eliska; Strnadel, Radim; Kuklová, Ivana; Woznicová, Vladana; Zákoucká, Hana; Smajs, David.

Acta Derm Venereol ; 92(6): 669-74, 2012 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-22434073

11.

Penicillin Treatment Failure in Rabbit Syphilis Due to the Persistence of Treponemes (Treponema paraluisleporidarum Ecovar Cuniculus) in the Focus of Infection.

Jekl, Vladimír; Nováková, Markéta; Jeklová, Edita; Pospísilová, Petra; Krenová, Jitka; Faldyna, Martin; Skoric, Misa; Smajs, David.

Front Vet Sci ; 8: 675631, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-34222401

12.

Complete Chromosomal Sequences of Two Borrelia miyamotoi Samples Obtained from Ixodes ricinus Eggs in Czechia.

Janecek, Jan; Nováková, Markéta; Oppelt, Jan; Pospísilová, Petra; Cunha, Anita; Silva, Ana Catarina; Dantong, Li; Smajs, David.

Microbiol Resour Announc ; 9(14)2020 Apr 02.

Artigo em Inglês | MEDLINE | ID: mdl-32241866

13.

A retrospective study on nested PCR detection of syphilis treponemes in clinical samples: PCR detection contributes to the diagnosis of syphilis in patients with seronegative and serodiscrepant results.

Vrbová, Eliska; Mikalová, Lenka; Grillová, Linda; Pospísilová, Petra; Strnadel, Radim; Dastychová, Eliska; Kojanová, Martina; Kreidlová, Miluse; Vanousová, Daniela; Rob, Filip; Procházka, Premysl; Krchnáková, Alena; Vasku, Vladimír; Woznicová, Vladana; Dvoráková Heroldová, Monika; Kuklová, Ivana; Zákoucká, Hana; Smajs, David.

PLoS One ; 15(8): e0237949, 2020.

Artigo em Inglês | MEDLINE | ID: mdl-32817658

14.

Identification of positively selected genes in human pathogenic treponemes: Syphilis-, yaws-, and bejel-causing strains differ in sets of genes showing adaptive evolution.

Maderánková, Denisa; Mikalová, Lenka; Strouhal, Michal; Vadják, Simon; Kuklová, Ivana; Pospísilová, Petra; Krbková, Lenka; Koscová, Pavlína; Provazník, Ivo; Smajs, David.

PLoS Negl Trop Dis ; 13(6): e0007463, 2019 06.

Artigo em Inglês | MEDLINE | ID: mdl-31216284

15.

MLST typing of Treponema pallidum subsp. pallidum in the Czech Republic during 2004-2017: Clinical isolates belonged to 25 allelic profiles and harbored 8 novel allelic variants.

Vrbová, Eliska; Grillová, Linda; Mikalová, Lenka; Pospísilová, Petra; Strnadel, Radim; Dastychová, Eliska; Kojanová, Martina; Kreidlová, Miluse; Vanousová, Daniela; Rob, Filip; Procházka, Premysl; Krchnáková, Alena; Vasku, Vladimír; Woznicová, Vladana; Dvoráková Heroldová, Monika; Kuklová, Ivana; Zákoucká, Hana; Smajs, David.

PLoS One ; 14(5): e0217611, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31150464

16.

Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens.

Grillová, Linda; Oppelt, Jan; Mikalová, Lenka; Nováková, Markéta; Giacani, Lorenzo; Niesnerová, Anezka; Noda, Angel A; Mechaly, Ariel E; Pospísilová, Petra; Cejková, Darina; Grange, Philippe A; Dupin, Nicolas; Strnadel, Radim; Chen, Marcus; Denham, Ian; Arora, Natasha; Picardeau, Mathieu; Weston, Christopher; Forsyth, R Allyn; Smajs, David.

Front Microbiol ; 10: 1691, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31417509

17.

Multi-locus sequence typing of Treponema pallidum subsp. pallidum present in clinical samples from France: Infecting treponemes are genetically diverse and belong to 18 allelic profiles.

Pospísilová, Petra; Grange, Philippe Alain; Grillová, Linda; Mikalová, Lenka; Martinet, Pervenche; Janier, Michel; Vermersch, Annie; Benhaddou, Nadjet; Del Giudice, Pascal; Alcaraz, Isabelle; Truchetet, François; Dupin, Nicolas; Smajs, David.

PLoS One ; 13(7): e0201068, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30024965

18.

Structure of rrn operons in pathogenic non-cultivable treponemes: sequence but not genomic position of intergenic spacers correlates with classification of Treponema pallidum and Treponema paraluiscuniculi strains.

Cejková, Darina; Zobaníková, Marie; Pospísilová, Petra; Strouhal, Michal; Mikalová, Lenka; Weinstock, George M; Smajs, David.

J Med Microbiol ; 62(Pt 2): 196-207, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23082031

19.

Resequencing of Treponema pallidum ssp. pallidum strains Nichols and SS14: correction of sequencing errors resulted in increased separation of syphilis treponeme subclusters.

Petrosová, Helena; Pospísilová, Petra; Strouhal, Michal; Cejková, Darina; Zobaníková, Marie; Mikalová, Lenka; Sodergren, Erica; Weinstock, George M; Smajs, David.

PLoS One ; 8(9): e74319, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-24058545

20.

Whole genome sequence of the Treponema Fribourg-Blanc: unspecified simian isolate is highly similar to the yaws subspecies.

Zobaníková, Marie; Strouhal, Michal; Mikalová, Lenka; Cejková, Darina; Ambrozová, Lenka; Pospísilová, Petra; Fulton, Lucinda L; Chen, Lei; Sodergren, Erica; Weinstock, George M; Smajs, David.

PLoS Negl Trop Dis ; 7(4): e2172, 2013.

Artigo em Inglês | MEDLINE | ID: mdl-23638193

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