Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials.

Wakkerman, Famke C; Wu, Jiqing; Putter, Hein; Jürgenliemk-Schulz, Ina M; Jobsen, Jan J; Lutgens, Ludy C H W; Haverkort, Marie A D; de Jong, Marianne A; Mens, Jan Willem M; Wortman, Bastiaan G; Nout, Remi A; Léon-Castillo, Alicia; Powell, Melanie E; Mileshkin, Linda R; Katsaros, Dionyssios; Alfieri, Joanne; Leary, Alexandra; Singh, Naveena; de Boer, Stephanie M; Nijman, Hans W; Smit, Vincent T H B M; Bosse, Tjalling; Koelzer, Viktor H; Creutzberg, Carien L; Horeweg, Nanda.

Lancet Oncol ; 2024 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-38701815

2.

Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry.

Vermij, Lisa; Jobsen, Jan J; León-Castillo, Alicia; Brinkhuis, Mariel; Roothaan, Suzan; Powell, Melanie E; de Boer, Stephanie M; Khaw, Pearly; Mileshkin, Linda R; Fyles, Anthony; Leary, Alexandra; Genestie, Catherine; Jürgenliemk-Schulz, Ina M; Crosbie, Emma J; Mackay, Helen J; Nijman, Hans W; Nout, Remi A; Smit, Vincent T H B M; Creutzberg, Carien L; Horeweg, Nanda; Bosse, Tjalling.

Br J Cancer ; 128(7): 1360-1368, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36690721

3.

Endometrial cancer.

Crosbie, Emma J; Kitson, Sarah J; McAlpine, Jessica N; Mukhopadhyay, Asima; Powell, Melanie E; Singh, Naveena.

Lancet ; 399(10333): 1412-1428, 2022 04 09.

Artigo em Inglês | MEDLINE | ID: mdl-35397864

4.

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.

Vermij, Lisa; Léon-Castillo, Alicia; Singh, Naveena; Powell, Melanie E; Edmondson, Richard J; Genestie, Catherine; Khaw, Pearly; Pyman, Jan; McLachlin, C Meg; Ghatage, Prafull; de Boer, Stephanie M; Nijman, Hans W; Smit, Vincent T H B M; Crosbie, Emma J; Leary, Alexandra; Creutzberg, Carien L; Horeweg, Nanda; Bosse, Tjalling.

Mod Pathol ; 35(10): 1475-1483, 2022 10.

Artigo em Inglês | MEDLINE | ID: mdl-35752743

5.

The role of radiotherapy in ovarian cancer.

Durno, Kimberley; Powell, Melanie E.

Int J Gynecol Cancer ; 32(3): 366-371, 2022 03.

Artigo em Inglês | MEDLINE | ID: mdl-35256425

6.

Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer.

Kokka, Fani; Bryant, Andrew; Olaitan, Adeola; Brockbank, Elly; Powell, Melanie; Oram, David.

Cochrane Database Syst Rev ; 8: CD010260, 2022 08 22.

Artigo em Inglês | MEDLINE | ID: mdl-35994243

7.

Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial.

de Boer, Stephanie M; Powell, Melanie E; Mileshkin, Linda; Katsaros, Dionyssios; Bessette, Paul; Haie-Meder, Christine; Ottevanger, Petronella B; Ledermann, Jonathan A; Khaw, Pearly; D'Amico, Romerai; Fyles, Anthony; Baron, Marie-Helene; Jürgenliemk-Schulz, Ina M; Kitchener, Henry C; Nijman, Hans W; Wilson, Godfrey; Brooks, Susan; Gribaudo, Sergio; Provencher, Diane; Hanzen, Chantal; Kruitwagen, Roy F; Smit, Vincent T H B M; Singh, Naveena; Do, Viet; Lissoni, Andrea; Nout, Remi A; Feeney, Amanda; Verhoeven-Adema, Karen W; Putter, Hein; Creutzberg, Carien L.

Lancet Oncol ; 20(9): 1273-1285, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31345626

8.

Endometrial cancer: the individual approach.

Powell, Melanie E.

Lancet Oncol ; 24(3): 201-203, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-37052963

9.

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial.

de Boer, Stephanie M; Powell, Melanie E; Mileshkin, Linda; Katsaros, Dionyssios; Bessette, Paul; Haie-Meder, Christine; Ottevanger, Petronella B; Ledermann, Jonathan A; Khaw, Pearly; Colombo, Alessandro; Fyles, Anthony; Baron, Marie-Helene; Jürgenliemk-Schulz, Ina M; Kitchener, Henry C; Nijman, Hans W; Wilson, Godfrey; Brooks, Susan; Carinelli, Silvestro; Provencher, Diane; Hanzen, Chantal; Lutgens, Ludy C H W; Smit, Vincent T H B M; Singh, Naveena; Do, Viet; D'Amico, Romerai; Nout, Remi A; Feeney, Amanda; Verhoeven-Adema, Karen W; Putter, Hein; Creutzberg, Carien L.

Lancet Oncol ; 19(3): 295-309, 2018 03.

Artigo em Inglês | MEDLINE | ID: mdl-29449189

10.

Refinement of high-risk endometrial cancer classification using DNA damage response biomarkers: a TransPORTEC initiative.

Auguste, Aurélie; Genestie, Catherine; De Bruyn, Marco; Adam, Julien; Le Formal, Audrey; Drusch, Françoise; Pautier, Patricia; Crosbie, Emma J; MacKay, Helen; Kitchener, Henry C; Powell, Melanie; Pollock, Pamela M; Mileshkin, Linda; Edmondson, Richard J; Nout, Remi; Nijman, Hans W; Creutzberg, Carien L; Bosse, Tjalling; Leary, Alexandra.

Mod Pathol ; 31(12): 1851-1861, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-29955143

11.

Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.

Kitson, Sarah; Sivalingam, Vanitha N; Bolton, James; McVey, Rhona; Nickkho-Amiry, Mashid; Powell, Melanie E; Leary, Alexandra; Nijman, Hans W; Nout, Remi A; Bosse, Tjalling; Renehan, Andrew G; Kitchener, Henry C; Edmondson, Richard J; Crosbie, Emma J.

Mod Pathol ; 30(3): 459-468, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-27910946

12.

Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial.

de Boer, Stephanie M; Powell, Melanie E; Mileshkin, Linda; Katsaros, Dionyssios; Bessette, Paul; Haie-Meder, Christine; Ottevanger, Petronella B; Ledermann, Jonathan A; Khaw, Pearly; Colombo, Alessandro; Fyles, Anthony; Baron, Marie-Helene; Kitchener, Henry C; Nijman, Hans W; Kruitwagen, Roy F; Nout, Remi A; Verhoeven-Adema, Karen W; Smit, Vincent T; Putter, Hein; Creutzberg, Carien L.

Lancet Oncol ; 17(8): 1114-1126, 2016 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-27397040

13.

Prognostic significance of L1CAM expression and its association with mutant p53 expression in high-risk endometrial cancer.

Van Gool, Inge C; Stelloo, Ellen; Nout, Remi A; Nijman, Hans W; Edmondson, Richard J; Church, David N; MacKay, Helen J; Leary, Alexandra; Powell, Melanie E; Mileshkin, Linda; Creutzberg, Carien L; Smit, Vincent T H B M; Bosse, Tjalling.

Mod Pathol ; 29(2): 174-81, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26743472

14.

Working together to shape the endometrial cancer research agenda: The top ten unanswered research questions.

Wan, Y Louise; Beverley-Stevenson, Rachel; Carlisle, Daloni; Clarke, Sinead; Edmondson, Richard J; Glover, Steve; Holland, Julie; Hughes, Carol; Kitchener, Henry C; Kitson, Sarah; Miles, Tracie; Morley, Richard; Morrison, Jo; Nelson, Linsey; Powell, Melanie; Sadler, Laura; Tomlinson, Anne; Tylko-Hill, Katharine; Whitcombe, Jo; Crosbie, Emma J.

Gynecol Oncol ; 143(2): 287-293, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-27593736

15.

Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial.

Symonds, R Paul; Gourley, Charlie; Davidson, Susan; Carty, Karen; McCartney, Elaine; Rai, Debbie; Banerjee, Susana; Jackson, David; Lord, Rosemary; McCormack, Mary; Hudson, Emma; Reed, Nicholas; Flubacher, Maxine; Jankowska, Petra; Powell, Melanie; Dive, Caroline; West, Catharine M L; Paul, James.

Lancet Oncol ; 16(15): 1515-1524, 2015 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-26474517

16.

Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative.

Stelloo, Ellen; Bosse, Tjalling; Nout, Remi A; MacKay, Helen J; Church, David N; Nijman, Hans W; Leary, Alexandra; Edmondson, Richard J; Powell, Melanie E; Crosbie, Emma J; Kitchener, Henry C; Mileshkin, Linda; Pollock, Pamela M; Smit, Vincent T; Creutzberg, Carien L.

Mod Pathol ; 28(6): 836-44, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25720322

17.

Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer.

Kokka, Fani; Bryant, Andrew; Brockbank, Elly; Powell, Melanie; Oram, David.

Cochrane Database Syst Rev ; (4): CD010260, 2015 Apr 07.

Artigo em Inglês | MEDLINE | ID: mdl-25847525

18.

ESTABLISHMENT OF ECHOCARDIOGRAPHIC PARAMETERS OF CLINICALLY HEALTHY FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS).

Gerlach, Trevor J; Estrada, Amara H; Sosa, Ivan S; Powell, Melanie; Lamb, Kenneth E; Ball, Ray L; de Wit, Martine; Walsh, Mike T.

J Zoo Wildl Med ; 46(2): 205-12, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-26056870

19.

Investigators' response.

Nout, Remi A; Powell, Melanie E; de Boer, Stephanie M; Creutzberg, Carien L.

Lancet Oncol ; 19(5): 602, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29726377

20.

Prediction of recurrence risk in endometrial cancer with multimodal deep learning.

Volinsky-Fremond, Sarah; Horeweg, Nanda; Andani, Sonali; Barkey Wolf, Jurriaan; Lafarge, Maxime W; de Kroon, Cor D; Ørtoft, Gitte; Høgdall, Estrid; Dijkstra, Jouke; Jobsen, Jan J; Lutgens, Ludy C H W; Powell, Melanie E; Mileshkin, Linda R; Mackay, Helen; Leary, Alexandra; Katsaros, Dionyssios; Nijman, Hans W; de Boer, Stephanie M; Nout, Remi A; de Bruyn, Marco; Church, David; Smit, Vincent T H B M; Creutzberg, Carien L; Koelzer, Viktor H; Bosse, Tjalling.

Nat Med ; 2024 May 24.

Artigo em Inglês | MEDLINE | ID: mdl-38789645

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Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials.

Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry.

Endometrial cancer.

p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial.

The role of radiotherapy in ovarian cancer.

Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer.

Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): patterns of recurrence and post-hoc survival analysis of a randomised phase 3 trial.

Endometrial cancer: the individual approach.

Adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): final results of an international, open-label, multicentre, randomised, phase 3 trial.

Refinement of high-risk endometrial cancer classification using DNA damage response biomarkers: a TransPORTEC initiative.

Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies.

Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial.

Prognostic significance of L1CAM expression and its association with mutant p53 expression in high-risk endometrial cancer.

Working together to shape the endometrial cancer research agenda: The top ten unanswered research questions.

Cediranib combined with carboplatin and paclitaxel in patients with metastatic or recurrent cervical cancer (CIRCCa): a randomised, double-blind, placebo-controlled phase 2 trial.

Refining prognosis and identifying targetable pathways for high-risk endometrial cancer; a TransPORTEC initiative.

Hysterectomy with radiotherapy or chemotherapy or both for women with locally advanced cervical cancer.

ESTABLISHMENT OF ECHOCARDIOGRAPHIC PARAMETERS OF CLINICALLY HEALTHY FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS).

Investigators' response.

Prediction of recurrence risk in endometrial cancer with multimodal deep learning.