Detalhe da pesquisa
1.
Structure of the cell-binding component of the Clostridium difficile binary toxin reveals a di-heptamer macromolecular assembly.
Proc Natl Acad Sci U S A
; 117(2): 1049-1058, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31896582
2.
The Importance of Therapeutically Targeting the Binary Toxin from Clostridioides difficile.
Int J Mol Sci
; 22(6)2021 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33805767
3.
Excision of 5-Carboxylcytosine by Thymine DNA Glycosylase.
J Am Chem Soc
; 141(47): 18851-18861, 2019 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31693361
4.
A plasmid borne, functionally novel glycoside hydrolase family 30 subfamily 8 endoxylanase from solventogenic Clostridium.
Biochem J
; 475(9): 1533-1551, 2018 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29626157
5.
Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues.
Nucleic Acids Res
; 44(21): 10248-10258, 2016 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27580719
6.
Short Carboxylic Acid-Carboxylate Hydrogen Bonds Can Have Fully Localized Protons.
Biochemistry
; 56(2): 391-402, 2017 Jan 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27989121
7.
Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA.
Nucleic Acids Res
; 43(19): 9541-52, 2015 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-26358812
8.
Structural Basis for Excision of 5-Formylcytosine by Thymine DNA Glycosylase.
Biochemistry
; 55(45): 6205-6208, 2016 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27805810
9.
A direct interaction between NQO1 and a chemotherapeutic dimeric naphthoquinone.
BMC Struct Biol
; 16: 1, 2016 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26822308
10.
Small-molecule inhibitors of ERK-mediated immediate early gene expression and proliferation of melanoma cells expressing mutated BRaf.
Biochem J
; 467(3): 425-38, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25695333
11.
Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA.
Proc Natl Acad Sci U S A
; 109(21): 8091-6, 2012 May 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22573813
12.
Ni(II) coordination to mixed sites modulates DNA binding of HpNikR via a long-range effect.
Proc Natl Acad Sci U S A
; 109(15): 5633-8, 2012 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22451934
13.
A novel member of glycoside hydrolase family 30 subfamily 8 with altered substrate specificity.
Acta Crystallogr D Biol Crystallogr
; 70(Pt 11): 2950-8, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25372685
14.
Structural and functional analysis of the pro-domain of human cathelicidin, LL-37.
Biochemistry
; 52(9): 1547-58, 2013 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23406372
15.
Techniques, tools and best practices for ligand electron-density analysis and results from their application to deposited crystal structures.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 2): 150-67, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385452
16.
Structure of human apurinic/apyrimidinic endonuclease 1 with the essential Mg2+ cofactor.
Acta Crystallogr D Biol Crystallogr
; 69(Pt 12): 2555-62, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311596
17.
Comment on Three X-ray Crystal Structure Papers.
J Immunol
; 196(2): 521-4, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26747564
18.
Additional Comment on Three X-ray Crystal Structure Papers.
J Immunol
; 196(2): 528-30, 2016 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26747567
19.
Visualizing ligand molecules in Twilight electron density.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 2): 195-200, 2013 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23385767
20.
Characterizing inhibitors of human AP endonuclease 1.
PLoS One
; 18(1): e0280526, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36652434