Detalhe da pesquisa
1.
Anti-epidermal growth factor receptor monoclonal antibody cetuximab inhibits EGFR/HER-2 heterodimerization and activation.
Int J Oncol
; 34(1): 25-32, 2009 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19082474
2.
In vivo method for establishing synergy between antibodies to epidermal growth factor receptor and vascular endothelial growth factor receptor-2.
Methods Mol Biol
; 525: 545-57, xv, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19252838
3.
Tumors established with cell lines selected for oxaliplatin resistance respond to oxaliplatin if combined with cetuximab.
Clin Cancer Res
; 13(24): 7432-40, 2007 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18094427
4.
Therapeutic implications of a human neutralizing antibody to the macrophage-stimulating protein receptor tyrosine kinase (RON), a c-MET family member.
Cancer Res
; 66(18): 9162-70, 2006 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16982759
5.
A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo.
Cancer Res
; 63(24): 8912-21, 2003 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-14695208
6.
Enhanced antitumor activity of anti-epidermal growth factor receptor monoclonal antibody IMC-C225 in combination with irinotecan (CPT-11) against human colorectal tumor xenografts.
Clin Cancer Res
; 8(5): 994-1003, 2002 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-12006511
7.
CCR 20th anniversary commentary: a chimeric antibody, C225, inhibits EGFR activation and tumor growth.
Clin Cancer Res
; 21(2): 227-9, 2015 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25593342
8.
Intrinsic Resistance to Cixutumumab Is Conferred by Distinct Isoforms of the Insulin Receptor.
Mol Cancer Res
; 13(12): 1615-26, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26263910
9.
A bi-functional antibody-receptor domain fusion protein simultaneously targeting IGF-IR and VEGF for degradation.
MAbs
; 7(5): 931-45, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26073904
10.
Conservation of receptor antagonist anti-tumor activity by epidermal growth factor receptor antibody expressed in transgenic corn seed.
Hum Antibodies
; 13(3): 81-90, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-15598988
11.
A human monoclonal antibody targeting the stem cell factor receptor (c-Kit) blocks tumor cell signaling and inhibits tumor growth.
Cancer Biol Ther
; 15(9): 1208-18, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24921944
12.
Preclinical rationale for combining an EGFR antibody with cisplatin/gemcitabine for the treatment of NSCLC.
Cancer Genomics Proteomics
; 9(2): 77-92, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22399498
13.
Estimating preclinical efficacy targets utilizing cetuximab efficacy in KRAS mutant and wild-type colorectal cancer models.
Anticancer Res
; 31(6): 2149-60, 2011 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-21737635
14.
Methods for evaluating effects of an irinotecan + 5-fluorouracil/leucovorin (IFL) regimen in an orthotopic metastatic colorectal cancer model utilizing in vivo bioluminescence imaging.
Methods Mol Biol
; 602: 235-52, 2010.
Artigo
em Inglês
| MEDLINE | ID: mdl-20012402
15.
Anti-transforming growth factor beta receptor II antibody has therapeutic efficacy against primary tumor growth and metastasis through multieffects on cancer, stroma, and immune cells.
Clin Cancer Res
; 16(4): 1191-205, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20145179
16.
Development of a fully human anti-PDGFRbeta antibody that suppresses growth of human tumor xenografts and enhances antitumor activity of an anti-VEGFR2 antibody.
Neoplasia
; 11(6): 594-604, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19484148
17.
An antibody directed against PDGF receptor beta enhances the antitumor and the anti-angiogenic activities of an anti-VEGF receptor 2 antibody.
Biochem Biophys Res Commun
; 357(4): 1142-7, 2007 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17462601
18.
A fully human recombinant IgG-like bispecific antibody to both the epidermal growth factor receptor and the insulin-like growth factor receptor for enhanced antitumor activity.
J Biol Chem
; 280(20): 19665-72, 2005 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15757893