[Liver damage caused by HIV infection]. / Porazhenie pecheni u infitsirovannykh virusom immunodefitsita cheloveka.

Hepatic status was studied in 7 HIV-infected patients at the stage of generalized lymphadenopathy. Intravital needle biopsy obtained from the livers characterizes the latter as enlarged, showing signs of protein-synthesis dysfunction, morphological evidence of mild cytolysis, cholestasis, moderate mesenchymal-inflammatory syndrome. The study of autopsy specimens obtained from hepatic tissue of the woman who had died of AIDS disclosed more advanced lesions: hepatocytes dystrophy, intralobular and periportal infiltration. The conclusion is made on the necessity of liver function examination entailing due therapeutic measures when following up patients with HIV infection and AIDS.

[Our experience with acycloguanosine treatment of herpes simplex]. / Opyt lecheniia prostogo gerpesa atsikloguanozinom.

A 5% ointment acycloguanosine was tried in the treatment of recurrent herpes simplex of the skin and genitalia in 48 patients. The treatment brought limitation of the process, relief of the symptoms, control of local manifestations and toxicity, accelerated epithelization, complete regression and disappearance of the eruption.

[Activities of a consultation and diagnostic polyclinic for AIDS and AIDS-related infections]. / O rabote konsul'tativno-diagnosticheskoi polikliniki "SPID i SPID-indikatornye infektsii.

The analysis of curative and diagnostic work of AIDS counselling and diagnostic units (CDU) showed that during a year and a half 15,000 people had been screened, 27 of these were identified as persons infected with human immunodeficiency virus (HIV) and 4 persons identified at other places, were registered for followup. It was found that 51.3 percent of people were screened anonymously, reason for screening being epidemiological indications--history of blood transfusions, homosexual contacts, irregular sexual intercourse. The rest did not observe anonymity, 10.7 percent of these persons were screened by clinical indications. The in-depth clinical screening of patients who sought care in CDU, patients infected with HIV and persons who had contacts with them, required the consultative services of different specialists--dermatovenerologists, gynaecologists, sexologists, stomatologists and some others. It determined the necessity of establishing an outpatient department of "AIDS and AIDS-indicatory infections" which represented a new organizational form of AIDS service.