Detalhe da pesquisa
1.
Functional evolution of IGF2:IGF2R domain 11 binding generates novel structural interactions and a specific IGF2 antagonist.
Proc Natl Acad Sci U S A
; 113(20): E2766-75, 2016 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27140600
2.
Systemically Administered Homing Peptide Targets Dystrophic Lesions and Delivers Transforming Growth Factor-ß (TGFß) Inhibitor to Attenuate Murine Muscular Dystrophy Pathology.
Pharmaceutics
; 13(9)2021 Sep 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34575582
3.
Structural insights into the interaction of insulin-like growth factor 2 with IGF2R domain 11.
Structure
; 15(9): 1065-78, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17850746
4.
Functional evaluation of novel soluble insulin-like growth factor (IGF)-II-specific ligand traps based on modified domain 11 of the human IGF2 receptor.
Mol Cancer Ther
; 6(2): 607-17, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17308058
5.
Kinetics of insulin-like growth factor II (IGF-II) interaction with domain 11 of the human IGF-II/mannose 6-phosphate receptor: function of CD and AB loop solvent-exposed residues.
J Mol Biol
; 359(2): 403-21, 2006 Jun 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-16631789
6.
An exon splice enhancer primes IGF2:IGF2R binding site structure and function evolution.
Science
; 338(6111): 1209-13, 2012 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23197533
7.
Structure and function of the human Gly1619Arg polymorphism of M6P/IGF2R domain 11 implicated in IGF2 dependent growth.
J Mol Endocrinol
; 42(4): 341-56, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19208780