Detalhe da pesquisa
1.
IKKß deletion from CNS macrophages increases neuronal excitability and accelerates the onset of EAE, while from peripheral macrophages reduces disease severity.
J Neuroinflammation
; 21(1): 34, 2024 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38279130
2.
Novel cell-based analysis reveals region-dependent changes in microglial dynamics in grey matter in a cuprizone model of demyelination.
Neurobiol Dis
; 157: 105449, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34274460
3.
Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKß promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice.
J Neuroinflammation
; 18(1): 222, 2021 Sep 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-34565380
4.
Exploiting the Role of Hypoxia-Inducible Factor 1 and Pseudohypoxia in the Myelodysplastic Syndrome Pathophysiology.
Int J Mol Sci
; 22(8)2021 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33921064
5.
Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis.
Int J Mol Sci
; 21(20)2020 Oct 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33066323
6.
Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF.
Int J Mol Sci
; 19(3)2018 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-29495345
7.
A Cyclic Altered Peptide Analogue Based on Myelin Basic Protein 87-99 Provides Lasting Prophylactic and Therapeutic Protection Against Acute Experimental Autoimmune Encephalomyelitis.
Molecules
; 23(2)2018 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29385090
8.
Altered expression of oligodendrocyte and neuronal marker genes predicts the clinical onset of autoimmune encephalomyelitis and indicates the effectiveness of multiple sclerosis-directed therapeutics.
J Immunol
; 192(9): 4122-33, 2014 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24683189
9.
Differential contributions of microglial and neuronal IKKß to synaptic plasticity and associative learning in alert behaving mice.
Glia
; 63(4): 549-66, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25297800
10.
Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models.
Acta Neuropathol
; 128(2): 247-66, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24622774
11.
Spontaneous human CD8 T cell and autoimmune encephalomyelitis-induced CD4/CD8 T cell lesions in the brain and spinal cord of HLA-DRB1*15-positive multiple sclerosis humanized immune system mice.
Elife
; 122024 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38900149
12.
Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-kappaB.
Brain
; 134(Pt 9): 2722-35, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21908876
13.
Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis.
Front Immunol
; 13: 972003, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36159850
14.
Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system.
J Immunol
; 183(12): 7877-89, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20007573
15.
TNF receptor I sensitizes neurons to erythropoietin- and VEGF-mediated neuroprotection after ischemic and excitotoxic injury.
Proc Natl Acad Sci U S A
; 105(16): 6185-90, 2008 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-18413601
16.
Comparative gene expression analysis in mouse models for multiple sclerosis, Alzheimer's disease and stroke for identifying commonly regulated and disease-specific gene changes.
Genomics
; 96(2): 82-91, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-20435134
17.
A National Representative, Cross-Sectional Study by the Hellenic Academy of NeuroImmunology (HEL.A.NI.) on COVID-19 and Multiple Sclerosis: Overall Impact and Willingness Toward Vaccination.
Front Neurol
; 12: 757038, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34899577
18.
TNFRI is a positive T-cell costimulatory molecule important for the timing of cytokine responses.
Immunol Cell Biol
; 88(5): 586-95, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20212506
19.
Gene expression profile associated with oncogenic ras-induced senescence, cell death, and transforming properties in human cells.
Cancer Invest
; 28(6): 563-87, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19883200
20.
Inflammation and Oxidative Stress in Multiple Sclerosis: Consequences for Therapy Development.
Oxid Med Cell Longev
; 2020: 7191080, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32454942