Detalhe da pesquisa
1.
The synthesis of 2,3,6-trisubstituted 1-oxo-1,2-dihydroisoquinolines as potent CRTh2 antagonists.
Bioorg Med Chem Lett
; 27(23): 5344-5348, 2017 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29110986
2.
Identification of highly potent and selective PI3Kδ inhibitors.
Bioorg Med Chem Lett
; 27(13): 2849-2853, 2017 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28209465
3.
Quality by design (QbD) of amide isosteres: 5,5-Disubstituted isoxazolines as potent CRTh2 antagonists with favorable pharmacokinetic and drug-like properties.
Bioorg Med Chem Lett
; 24(6): 1615-20, 2014 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24556380
4.
DGKα/ζ inhibitors combine with PD-1 checkpoint therapy to promote T cell-mediated antitumor immunity.
Sci Transl Med
; 15(719): eadh1892, 2023 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37878674
5.
Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 2.
Bioorg Med Chem Lett
; 21(24): 7287-90, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22078214
6.
Synthesis and SAR development of novel P2X7 receptor antagonists for the treatment of pain: part 1.
Bioorg Med Chem Lett
; 21(12): 3805-8, 2011 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21570840
7.
3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists.
Bioorg Med Chem Lett
; 18(1): 228-31, 2008 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18006311
8.
Synthesis and structure-activity relationships of heteroaryl substituted-3,4-diamino-3-cyclobut-3-ene-1,2-dione CXCR2/CXCR1 receptor antagonists.
Bioorg Med Chem Lett
; 18(4): 1318-22, 2008 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18242983
9.
Discovery of MK-8318, a Potent and Selective CRTh2 Receptor Antagonist for the Treatment of Asthma.
ACS Med Chem Lett
; 9(7): 679-684, 2018 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30034600
10.
The effect of cadmium on the growth and antioxidant response for freshwater algae Chlorella vulgaris.
Springerplus
; 5(1): 1290, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27652004
11.
Identification of full, partial and inverse CC chemokine receptor 3 agonists using [35S]GTPgammaS binding.
Eur J Pharmacol
; 456(1-3): 1-10, 2002 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-12450563
12.
Isolation, structure elucidation and antibacterial activity of a new tetramic acid, ascosetin.
J Antibiot (Tokyo)
; 67(7): 527-31, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24690911
13.
Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.
J Pharmacol Exp Ther
; 322(2): 477-85, 2007 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-17496166