Detalhe da pesquisa
1.
Novel neuroactive steroids as positive allosteric modulators of NMDA receptors: mechanism, site of action, and rescue pharmacology on GRIN variants associated with neurological conditions.
Cell Mol Life Sci
; 80(2): 42, 2023 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36645496
2.
Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis.
Brain
; 143(9): 2709-2720, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32830245
3.
Positive Allosteric Modulation as a Potential Therapeutic Strategy in Anti-NMDA Receptor Encephalitis.
J Neurosci
; 38(13): 3218-3229, 2018 03 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29476014
4.
EEG-ß/γ spectral power elevation in rat: a translatable biomarker elicited by GABA(Aα2/3)-positive allosteric modulators at nonsedating anxiolytic doses.
J Neurophysiol
; 113(1): 116-31, 2015 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25253471
5.
Pharmacological characterization of SAGE-718, a novel positive allosteric modulator of N-methyl-d-aspartate receptors.
Br J Pharmacol
; 181(7): 1028-1050, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37698384
6.
Allopregnanolone Mediates Affective Switching Through Modulation of Oscillatory States in the Basolateral Amygdala.
Biol Psychiatry
; 91(3): 283-293, 2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34561029
7.
SAGE-718: A First-in-Class N-Methyl-d-Aspartate Receptor Positive Allosteric Modulator for the Potential Treatment of Cognitive Impairment.
J Med Chem
; 65(13): 9063-9075, 2022 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35785990
8.
Stimulus-specific adaptation in auditory cortex is an NMDA-independent process distinct from the sensory novelty encoded by the mismatch negativity.
J Neurosci
; 30(49): 16475-84, 2010 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-21147987
9.
Representation of spatial goals in rat orbitofrontal cortex.
Neuron
; 51(4): 495-507, 2006 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16908414
10.
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.
J Neurosci
; 29(45): 14271-86, 2009 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-19906975
11.
Preclinical characterization of zuranolone (SAGE-217), a selective neuroactive steroid GABAA receptor positive allosteric modulator.
Neuropharmacology
; 181: 108333, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32976892
12.
Neuroactive Steroid N-Methyl-d-aspartate Receptor Positive Allosteric Modulators: Synthesis, SAR, and Pharmacological Activity.
J Med Chem
; 62(16): 7526-7542, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31390523
13.
Hippocampal CA3 NMDA receptors are crucial for memory acquisition of one-time experience.
Neuron
; 38(2): 305-15, 2003 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-12718863
14.
Adjunctive Lanicemine (AZD6765) in Patients with Major Depressive Disorder and History of Inadequate Response to Antidepressants: A Randomized, Placebo-Controlled Study.
Neuropsychopharmacology
; 42(4): 844-853, 2017 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27681442
15.
The Role of Lean Process Improvement in Implementation of Evidence-Based Practices in Behavioral Health Care.
J Behav Health Serv Res
; 42(4): 504-18, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-24464179
16.
A defined network of fast-spiking interneurons in orbitofrontal cortex: responses to behavioral contingencies and ketamine administration.
Front Syst Neurosci
; 3: 13, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-20057934
17.
Selective alpha7 nicotinic receptor activation by AZD0328 enhances cortical dopamine release and improves learning and attentional processes.
Biochem Pharmacol
; 78(7): 880-8, 2009 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19615981
18.
Personality assessment in today's health care environment: therapeutic alliance and patient satisfaction.
J Pers Assess
; 89(2): 95-104, 2007 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-17764387
19.
Dynamic analyses of information encoding in neural ensembles.
Neural Comput
; 16(2): 277-307, 2004 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15006097
20.
Requirement for hippocampal CA3 NMDA receptors in associative memory recall.
Science
; 297(5579): 211-8, 2002 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-12040087