Detalhe da pesquisa
1.
Discrete cytosolic macromolecular BRAF complexes exhibit distinct activities and composition.
EMBO J
; 36(5): 646-663, 2017 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28093501
2.
Activation loop phosphorylation regulates B-Raf in vivo and transformation by B-Raf mutants.
EMBO J
; 35(2): 143-61, 2016 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26657898
3.
Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.
EMBO J
; 31(11): 2629-47, 2012 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22510884
4.
Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma.
Int J Cancer
; 129(9): 2297-303, 2011 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21190184
5.
Identification and characterization of a BRAF fusion oncoprotein with retained autoinhibitory domains.
Oncogene
; 39(4): 814-832, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31558800
6.
Design and Synthesis of Type-IV Inhibitors of BRAF Kinase That Block Dimerization and Overcome Paradoxical MEK/ERK Activation.
J Med Chem
; 62(8): 3886-3897, 2019 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30977659
7.
Phospho-proteomic analyses of B-Raf protein complexes reveal new regulatory principles.
Oncotarget
; 7(18): 26628-52, 2016 May 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27034005
8.
Aberrant B-Raf signaling in human cancer -- 10 years from bench to bedside.
Crit Rev Oncog
; 17(1): 97-121, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22471666