Detalhe da pesquisa
1.
Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.
Mol Ther
; 32(3): 663-677, 2024 Mar 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38273654
2.
Precise correction of a spectrum of ß-thalassemia mutations in coding and non-coding regions by base editors.
Mol Ther Nucleic Acids
; 35(2): 102205, 2024 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38817682
3.
Correlating the differences in the receptor binding domain of SARS-CoV-2 spike variants on their interactions with human ACE2 receptor.
Sci Rep
; 13(1): 8743, 2023 05 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37253762
4.
Genome Engineering of Hematopoietic Stem Cells Using CRISPR/Cas9 System.
Methods Mol Biol
; 2429: 307-331, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35507170
5.
Erythroid lineage-specific lentiviral RNAi vectors suitable for molecular functional studies and therapeutic applications.
Sci Rep
; 12(1): 14033, 2022 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35982069
6.
Preferential Expansion of Human CD34+CD133+CD90+ Hematopoietic Stem Cells Enhances Gene-Modified Cell Frequency for Gene Therapy.
Hum Gene Ther
; 33(3-4): 188-201, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34486377
7.
Efficient and error-free correction of sickle mutation in human erythroid cells using prime editor-2.
Front Genome Ed
; 4: 1085111, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36605051
8.
Identification of novel HPFH-like mutations by CRISPR base editing that elevate the expression of fetal hemoglobin.
Elife
; 112022 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35147495
9.
Direct Generation of Immortalized Erythroid Progenitor Cell Lines from Peripheral Blood Mononuclear Cells.
Cells
; 10(3)2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33804564
10.
Amelioration of oxidative stress in differentiated neuronal cells by rutin regulated by a concentration switch.
Biomed Pharmacother
; 108: 15-26, 2018 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-30212708