Detalhe da pesquisa
1.
RAF-Mutant Melanomas Differentially Depend on ERK2 Over ERK1 to Support Aberrant MAPK Pathway Activation and Cell Proliferation.
Mol Cancer Res
; 19(6): 1063-1075, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33707308
2.
A Proof of Concept for Biomarker-Guided Targeted Therapy against Ovarian Cancer Based on Patient-Derived Tumor Xenografts.
Cancer Res
; 80(19): 4278-4287, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32747364
3.
Distinct Transcriptional Programming Drive Response to MAPK Inhibition in BRAF V600-Mutant Melanoma Patient-Derived Xenografts.
Mol Cancer Ther
; 18(12): 2421-2432, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31527224
4.
Hyperactivation of MAPK Signaling Is Deleterious to RAS/RAF-mutant Melanoma.
Mol Cancer Res
; 17(1): 199-211, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30201825
5.
Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss.
Nat Med
; 25(1): 95-102, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30559422
6.
Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer.
Oncogene
; 38(37): 6399-6413, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31324888
7.
The Lineage Determining Factor GRHL2 Collaborates with FOXA1 to Establish a Targetable Pathway in Endocrine Therapy-Resistant Breast Cancer.
Cell Rep
; 29(4): 889-903.e10, 2019 10 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31644911
8.
Combined ALK and MDM2 inhibition increases antitumor activity and overcomes resistance in human ALK mutant neuroblastoma cell lines and xenograft models.
Elife
; 62017 04 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28425916
9.
FGFR-Mediated Reactivation of MAPK Signaling Attenuates Antitumor Effects of Imatinib in Gastrointestinal Stromal Tumors.
Cancer Discov
; 5(4): 438-51, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25673643
10.
An F876L mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (enzalutamide).
Cancer Discov
; 3(9): 1030-43, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23842682