Detalhe da pesquisa
1.
Neurotoxins from snake venoms and α-conotoxin ImI inhibit functionally active ionotropic γ-aminobutyric acid (GABA) receptors.
J Biol Chem
; 290(37): 22747-58, 2015 Sep 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26221036
2.
Pentameric ligand-gated ion channel ELIC is activated by GABA and modulated by benzodiazepines.
Proc Natl Acad Sci U S A
; 109(44): E3028-34, 2012 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-23035248
3.
Unexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ ß- Site.
Neurochem Res
; 39(6): 1057-1067, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24072672
4.
Azemiopsin from Azemiops feae viper venom, a novel polypeptide ligand of nicotinic acetylcholine receptor.
J Biol Chem
; 287(32): 27079-86, 2012 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-22613724
5.
Search for α3ß2/3γ2 subtype selective ligands that are stable on human liver microsomes.
Bioorg Med Chem
; 21(1): 93-101, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23218469
6.
The GABAA receptor alpha+beta- interface: a novel target for subtype selective drugs.
J Neurosci
; 31(3): 870-7, 2011 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-21248110
7.
Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin.
J Biol Chem
; 286(43): 37702-11, 2011 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-21880742
8.
6,3'-Dinitroflavone is a low efficacy modulator of GABA(A) receptors.
Eur J Pharmacol
; 591(1-3): 142-6, 2008 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-18639544
9.
Mutagenesis and computational docking studies support the existence of a histamine binding site at the extracellular ß3+ß3- interface of homooligomeric ß3 GABAA receptors.
Neuropharmacology
; 108: 252-63, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27140694
10.
GABA(A) receptor subtype-selectivity of novel bicuculline derivatives.
Curr Med Chem
; 22(6): 771-80, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25386826
11.
Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects.
Brain Res
; 1554: 36-48, 2014 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24472579
12.
Subtype selectivity of α+ß- site ligands of GABAA receptors: identification of the first highly specific positive modulators at α6ß2/3γ2 receptors.
Br J Pharmacol
; 169(2): 384-99, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23472935
13.
A novel GABA(A) receptor pharmacology: drugs interacting with the α(+) ß(-) interface.
Br J Pharmacol
; 166(2): 476-85, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22074382
14.
The point mutation gamma 2F77I changes the potency and efficacy of benzodiazepine site ligands in different GABAA receptor subtypes.
Eur J Pharmacol
; 636(1-3): 18-27, 2010 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20303942
15.
Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats?
Prog Neuropsychopharmacol Biol Psychiatry
; 34(2): 376-86, 2010 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-20074611
16.
Anxiolytic-like effects of 8-acetylene imidazobenzodiazepines in a rhesus monkey conflict procedure.
Neuropharmacology
; 59(7-8): 612-8, 2010 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-20727364
17.
Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models.
J Med Chem
; 52(7): 1795-8, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19275170
18.
Identification of amino acid residues important for assembly of GABA receptor alpha1 and gamma2 subunits.
J Neurochem
; 96(4): 983-95, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16412095