Detalhe da pesquisa
1.
Evolving concepts in meningioma management in the era of genomics.
Cancer
; 2024 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753473
2.
mTOR kinase inhibition disrupts neuregulin 1-ERBB3 autocrine signaling and sensitizes NF2-deficient meningioma cellular models to IGF1R inhibition.
J Biol Chem
; 296: 100157, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33273014
3.
First International Conference on RASopathies and Neurofibromatoses in Asia: Identification and advances of new therapeutics.
Am J Med Genet A
; 179(6): 1091-1097, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30908877
4.
The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis.
Am J Med Genet A
; 173(6): 1714-1721, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28436162
5.
Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.
Neurobiol Dis
; 82: 22-31, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26019056
6.
CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies.
Am J Med Genet A
; 164A(3): 563-78, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24443315
7.
Preclinical evaluation of the third-generation, bi-steric mechanistic target of rapamycin complex 1-selective inhibitor RMC-6272 in NF2-deficient models.
Neurooncol Adv
; 6(1): vdae024, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38476930
8.
Erratum: Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2.
Mol Ther Methods Clin Dev
; 32(2): 101262, 2024 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38745896
9.
The E3 ubiquitin ligase protein associated with Myc (Pam) regulates mammalian/mechanistic target of rapamycin complex 1 (mTORC1) signaling in vivo through N- and C-terminal domains.
J Biol Chem
; 287(36): 30063-72, 2012 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-22798074
10.
Translatome analysis of Tuberous Sclerosis Complex-1 patient-derived neural progenitor cells reveal rapamycin-dependent and independent alterations.
Res Sq
; 2023 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37034588
11.
Proteasomal pathway inhibition as a potential therapy for NF2-associated meningioma and schwannoma.
Neuro Oncol
; 25(9): 1617-1630, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36806881
12.
Prospective phase II trial of the dual mTORC1/2 inhibitor vistusertib for progressive or symptomatic meningiomas in persons with neurofibromatosis 2.
Neurooncol Adv
; 5(1): vdad041, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37215956
13.
Translatome analysis of tuberous sclerosis complex 1 patient-derived neural progenitor cells reveals rapamycin-dependent and independent alterations.
Mol Autism
; 14(1): 39, 2023 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37880800
14.
Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2.
Mol Ther Methods Clin Dev
; 26: 169-180, 2022 Sep 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35846573
15.
SMARCE1 deficiency generates a targetable mSWI/SNF dependency in clear cell meningioma.
Nat Genet
; 54(6): 861-873, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35681054
16.
Back to the future: proceedings from the 2010 NF Conference.
Am J Med Genet A
; 155A(2): 307-21, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21271647
17.
Gene therapy for tuberous sclerosis complex type 2 in a mouse model by delivery of AAV9 encoding a condensed form of tuberin.
Sci Adv
; 7(2)2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33523984
18.
High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy.
Sci Rep
; 11(1): 17029, 2021 08 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426604
19.
Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK.
PLoS One
; 16(7): e0252048, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34264955
20.
What's new in neurofibromatosis? Proceedings from the 2009 NF Conference: new frontiers.
Am J Med Genet A
; 152A(2): 269-83, 2010 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-20082461