Detalhe da pesquisa
1.
Fibrillin-1 deficiency in the outer perichondrium causes longitudinal bone overgrowth in mice with Marfan syndrome.
Hum Mol Genet
; 31(19): 3281-3289, 2022 09 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-35567544
2.
The role of LTBPs in TGF beta signaling.
Dev Dyn
; 251(1): 95-104, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33742701
3.
Inhibition of HIPK2 Alleviates Thoracic Aortic Disease in Mice With Progressively Severe Marfan Syndrome.
Arterioscler Thromb Vasc Biol
; 41(9): 2483-2493, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34320838
4.
The Multiple Functions of Fibrillin-1 Microfibrils in Organismal Physiology.
Int J Mol Sci
; 23(3)2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163812
5.
Therapies for Thoracic Aortic Aneurysms and Acute Aortic Dissections.
Arterioscler Thromb Vasc Biol
; 39(2): 126-136, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30651002
6.
Therapeutics Targeting Drivers of Thoracic Aortic Aneurysms and Acute Aortic Dissections: Insights from Predisposing Genes and Mouse Models.
Annu Rev Med
; 68: 51-67, 2017 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28099082
7.
Cell Type-Specific Contributions of the Angiotensin II Type 1a Receptor to Aorta Homeostasis and Aneurysmal Disease-Brief Report.
Arterioscler Thromb Vasc Biol
; 38(3): 588-591, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29371244
8.
Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.
Proc Natl Acad Sci U S A
; 112(45): 14012-7, 2015 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-26494287
9.
Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice.
PLoS Genet
; 11(6): e1005340, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-26114882
10.
Dimorphic effects of transforming growth factor-ß signaling during aortic aneurysm progression in mice suggest a combinatorial therapy for Marfan syndrome.
Arterioscler Thromb Vasc Biol
; 35(4): 911-7, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25614286
11.
Angiotensin II type 1 receptor blockade attenuates TGF-beta-induced failure of muscle regeneration in multiple myopathic states.
Nat Med
; 13(2): 204-10, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17237794
12.
Clinical, diagnostic, and therapeutic aspects of the Marfan syndrome.
Adv Exp Med Biol
; 802: 77-94, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24443022
13.
EHD2 shuttles to the nucleus and represses transcription.
Biochem J
; 444(3): 383-94, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22448906
14.
Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome.
Nat Genet
; 33(3): 407-11, 2003 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-12598898
15.
Dissecting aortic aneurysm in Marfan syndrome is associated with losartan-sensitive transcriptomic modulation of aortic cells.
JCI Insight
; 8(10)2023 05 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37022786
16.
Generation of Fbn1 conditional null mice implicates the extracellular microfibrils in osteoprogenitor recruitment.
Genesis
; 50(8): 635-41, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22374917
17.
Differential effects of alendronate and losartan therapy on osteopenia and aortic aneurysm in mice with severe Marfan syndrome.
Hum Mol Genet
; 19(24): 4790-8, 2010 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20871099
18.
Fibrillin-1 genetic deficiency leads to pathological ageing of arteries in mice.
J Pathol
; 224(1): 33-44, 2011 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-21432852
19.
Krüppel-like factor 7 is required for olfactory bulb dopaminergic neuron development.
Exp Cell Res
; 317(4): 464-73, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21093432
20.
Pathophysiology and Therapeutics of Thoracic Aortic Aneurysm in Marfan Syndrome.
Biomolecules
; 12(1)2022 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35053276