Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Risk factors for more rapid progression of severe liver fibrosis in children with cystic fibrosis-related liver disease: A multi-center study validated by liver biopsy.

Sakhuja, Shruti; Staples, Heather M; Minard, Charles G; Ramm, Louise E; Lewindon, Peter J; Ramm, Grant A; Leung, Daniel H.

Liver Int ; 43(6): 1277-1286, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37035868

2.

Growth Hormone Stops Excessive Inflammation After Partial Hepatectomy, Allowing Liver Regeneration and Survival Through Induction of H2-Bl/HLA-G.

Ishikawa, Mayumi; Brooks, Andrew J; Fernández-Rojo, Manuel A; Medina, Johan; Chhabra, Yash; Minami, Shiro; Tunny, Kathryn A; Parton, Robert G; Vivian, Julian P; Rossjohn, Jamie; Chikani, Viral; Ramm, Grant A; Ho, Ken K Y; Waters, Michael J.

Hepatology ; 73(2): 759-775, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-32342533

3.

Synthetic peptides derived from the Schistosoma mansoni secretory protein Sm16 induce contrasting responses in hepatic stellate cells.

Carson, Jack P; Robinson, Mark W; Ramm, Grant A; Gobert, Geoffrey N.

Exp Parasitol ; 236-237: 108255, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35385714

4.

TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.

Dwyer, Benjamin J; Jarman, Edward J; Gogoi-Tiwari, Jully; Ferreira-Gonzalez, Sofia; Boulter, Luke; Guest, Rachel V; Kendall, Timothy J; Kurian, Dominic; Kilpatrick, Alastair M; Robson, Andrew J; O'Duibhir, Eoghan; Man, Tak Yung; Campana, Lara; Starkey Lewis, Philip J; Wigmore, Stephen J; Olynyk, John K; Ramm, Grant A; Tirnitz-Parker, Janina E E; Forbes, Stuart J.

J Hepatol ; 74(4): 860-872, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33221352

5.

Utility of Serum Biomarker Indices for Staging of Hepatic Fibrosis Before and After Venesection in Patients With Hemochromatosis Caused by Variants in HFE.

Chin, Justin; Powell, Lawrie W; Ramm, Louise E; Hartel, Gunter F; Olynyk, John K; Ramm, Grant A.

Clin Gastroenterol Hepatol ; 19(7): 1459-1468.e5, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-32745684

6.

Cost-Effectiveness of a Serum Biomarker Test for Risk-Stratified Liver Ultrasound Screening for Hepatocellular Carcinoma.

Carter, Hannah E; Jeffrey, Gary P; Ramm, Grant A; Gordon, Louisa G.

Value Health ; 24(10): 1454-1462, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34593168

7.

RNA sequencing of LX-2 cells treated with TGF-ß1 identifies genes associated with hepatic stellate cell activation.

Carson, Jack P; Robinson, Mark W; Ramm, Grant A; Gobert, Geoffrey N.

Mol Biol Rep ; 48(12): 7677-7688, 2021 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-34648138

8.

The Role of Sonic Hedgehog in Human Holoprosencephaly and Short-Rib Polydactyly Syndromes.

Loo, Christine K C; Pearen, Michael A; Ramm, Grant A.

Int J Mol Sci ; 22(18)2021 Sep 12.

Artigo em Inglês | MEDLINE | ID: mdl-34576017

9.

Hemochromatosis.

Olynyk, John K; Ramm, Grant A.

N Engl J Med ; 387(23): 2159-2170, 2022 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-36477033

10.

Regression of Fibrosis Stage With Treatment Reduces Long-Term Risk of Liver Cancer in Patients With Hemochromatosis Caused by Mutation in HFE.

Bardou-Jacquet, Edouard; Morandeau, Emilie; Anderson, Gregory J; Ramm, Grant A; Ramm, Louise E; Morcet, Jeff; Bouzille, Guillaume; Dixon, Jeannette; Clouston, Andrew D; Lainé, Fabrice; Turlin, Bruno; Powell, Lawrie W; Deugnier, Yves M.

Clin Gastroenterol Hepatol ; 18(8): 1851-1857, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-31622736

11.

Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.

Secondes, Eriza S; Wallace, Daniel F; Rishi, Gautam; McLaren, Gordon D; McLaren, Christine E; Chen, Wen-Pin; Ramm, Louise E; Powell, Lawrie W; Ramm, Grant A; Barton, James C; Subramaniam, V Nathan.

Blood Cells Mol Dis ; 85: 102463, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32652459

12.

Phenotypic analysis of hemochromatosis subtypes reveals variations in severity of iron overload and clinical disease.

Sandhu, Kam; Flintoff, Kaledas; Chatfield, Mark D; Dixon, Jeannette L; Ramm, Louise E; Ramm, Grant A; Powell, Lawrie W; Subramaniam, V Nathan; Wallace, Daniel F.

Blood ; 132(1): 101-110, 2018 07 05.

Artigo em Inglês | MEDLINE | ID: mdl-29743178

13.

Normal liver stiffness and influencing factors in healthy children: An individual participant data meta-analysis.

Li, Darrick K; Khan, Muhammad Rehan; Wang, Zhen; Chongsrisawat, Voranush; Swangsak, Panida; Teufel-Schäfer, Ulrike; Engelmann, Guido; Goldschmidt, Imeke; Baumann, Ulrich; Tokuhara, Daisuke; Cho, Yuki; Rowland, Marion; Mjelle, Anders B; Ramm, Grant A; Lewindon, Peter J; Witters, Peter; Cassiman, David; Ciuca, Ioana M; Prokop, Larry D; Haffar, Samir; Corey, Kathleen E; Murad, M H; Furuya, Katryn N; Bazerbachi, Fateh.

Liver Int ; 40(11): 2602-2611, 2020 11.

Artigo em Inglês | MEDLINE | ID: mdl-32901449

14.

Live imaging of collagen deposition during experimental hepatic schistosomiasis and recovery: a view on a dynamic process.

Harvie, Marina C G; McManus, Donald P; You, Hong; Rivera, Vanessa A; Nawaratna, Sujeevi K; MacDonald, Kelli P A; Ramm, Grant A; Gobert, Geoffrey N.

Lab Invest ; 99(2): 231-243, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30401957

15.

Accuracy of Transient Elastography Data Combined With APRI in Detection and Staging of Liver Disease in Pediatric Patients With Cystic Fibrosis.

Lewindon, Peter J; Puertolas-Lopez, Mora V; Ramm, Louise E; Noble, Charlton; Pereira, Tamara N; Wixey, Julie A; Hartel, Gunter F; Calvopina, Diego A; Leung, Daniel H; Ramm, Grant A.

Clin Gastroenterol Hepatol ; 17(12): 2561-2569.e5, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-30880274

16.

Detection of HFE Haemochromatosis in the clinic and community using standard erythrocyte tests.

Adris, Niwansa; Hazeldine, Simon; Bentley, Peter; Trinder, Debbie; Chua, Anita C G; Powell, Lawrie W; Ramm, Louise E; Ramm, Grant A; Olynyk, John K.

Blood Cells Mol Dis ; 74: 18-24, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30340937

17.

MicroRNA Sequencing Identifies a Serum MicroRNA Panel, Which Combined With Aspartate Aminotransferase to Platelet Ratio Index Can Detect and Monitor Liver Disease in Pediatric Cystic Fibrosis.

Calvopina, Diego A; Chatfield, Mark D; Weis, Anna; Coleman, Miranda A; Fernandez-Rojo, Manuel A; Noble, Charlton; Ramm, Louise E; Leung, Daniel H; Lewindon, Peter J; Ramm, Grant A.

Hepatology ; 68(6): 2301-2316, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30014495

18.

Serum MicroRNAs as Biomarkers in Hepatitis C: Preliminary Evidence of a MicroRNA Panel for the Diagnosis of Hepatocellular Carcinoma.

Weis, Anna; Marquart, Louise; Calvopina, Diego A; Genz, Berit; Ramm, Grant A; Skoien, Richard.

Int J Mol Sci ; 20(4)2019 Feb 17.

Artigo em Inglês | MEDLINE | ID: mdl-30781550

19.

Taurocholate Induces Biliary Differentiation of Liver Progenitor Cells Causing Hepatic Stellate Cell Chemotaxis in the Ductular Reaction: Role in Pediatric Cystic Fibrosis Liver Disease.

Pozniak, Katarzyna N; Pearen, Michael A; Pereira, Tamara N; Kramer, Cynthia S M; Kalita-De Croft, Priyakshi; Nawaratna, Sujeevi K; Fernandez-Rojo, Manuel A; Gobert, Geoffrey N; Tirnitz-Parker, Janina E E; Olynyk, John K; Shepherd, Ross W; Lewindon, Peter J; Ramm, Grant A.

Am J Pathol ; 187(12): 2744-2757, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28935574

20.

Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.

Barton, James C; McLaren, Christine E; Chen, Wen-Pin; Ramm, Grant A; Anderson, Gregory J; Powell, Lawrie W; Subramaniam, V Nathan; Adams, Paul C; Phatak, Pradyumna D; Gurrin, Lyle C; Phillips, John D; Parker, Charles J; Emond, Mary J; McLaren, Gordon D.

Ann Hepatol ; 17(5): 871-879, 2018 Aug 24.

Artigo em Inglês | MEDLINE | ID: mdl-30145563

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