Detalhe da pesquisa
1.
Glucocorticoids regulate lipid mediator networks by reciprocal modulation of 15-lipoxygenase isoforms affecting inflammation resolution.
Proc Natl Acad Sci U S A
; 120(35): e2302070120, 2023 08 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-37603745
2.
Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation.
J Immunol
; 203(4): 1031-1043, 2019 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31300512
3.
Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome.
FASEB J
; 33(5): 6140-6153, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30735438
4.
Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M1 agonists.
Bioorg Med Chem Lett
; 25(19): 4158-63, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26299349
5.
Rotational constriction of curcuminoids impacts 5-lipoxygenase and mPGES-1 inhibition and evokes a lipid mediator class switch in macrophages.
Biochem Pharmacol
; 203: 115202, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35932797
6.
From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution.
Acta Pharm Sin B
; 11(6): 1629-1647, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34221873
7.
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes.
Biochem Pharmacol
; 175: 113858, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32061774
8.
Staphylococcus aureus-Derived α-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution.
Cell Rep
; 33(2): 108247, 2020 10 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33053344
9.
Bioactivity and Mode of Action of Bacterial Tetramic Acids.
ACS Chem Biol
; 14(8): 1693-1697, 2019 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31294961
10.
Stereoselective total synthesis of parthenolides indicates target selectivity for tubulin carboxypeptidase activity.
Chem Sci
; 10(31): 7358-7364, 2019 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31489157
11.
MicroRNA5123p is upregulated, and promotes proliferation and cell cycle progression, in prostate cancer cells.
Mol Med Rep
; 17(1): 586-593, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29115469
12.
Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase.
Biochem Pharmacol
; 130: 71-82, 2017 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28189727
13.
Steroidal Ammonium Compounds as New Neuromuscular Blocking Agents.
Chem Biol Drug Des
; 87(5): 773-83, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26684806
14.
3,16-Bisquaternary ammonium steroid derivatives as neuromuscular blocking agents: synthesis and biological evaluation.
Steroids
; 96: 103-14, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25637675
15.
Design and synthesis of 6-oxo-1,4,5,6-tetrahydropyrimidine-5-carboxylate derivatives as neuraminidase inhibitors.
Eur J Med Chem
; 83: 466-73, 2014 Aug 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24992074
16.
Synthesis and activity evaluation of tilorone analogs as potential anticancer agents.
Eur J Med Chem
; 64: 432-41, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-23665799
17.
16-morpholino quaternary ammonium steroidal derivatives as neuromuscular blocking agents: synthesis, biological evaluation and in silico probe of ligand-receptor interaction.
Eur J Med Chem
; 56: 332-47, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22910136