Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Improved Î³-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases.

Zhang, Yao; Luan, Xiao; Zhang, Huaiyuan; Garre, Victoriano; Song, Yuanda; Ratledge, Colin.

Microb Cell Fact ; 16(1): 113, 2017 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-28637506

2.

Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling.

Jones, Christopher M; Wells, Ryan M; Madduri, Ashoka V R; Renfrow, Matthew B; Ratledge, Colin; Moody, D Branch; Niederweis, Michael.

Proc Natl Acad Sci U S A ; 111(5): 1945-50, 2014 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-24497493

3.

Proteomics analysis of high lipid-producing strain Mucor circinelloides WJ11: an explanation for the mechanism of lipid accumulation at the proteomic level.

Tang, Xin; Zan, Xinyi; Zhao, Lina; Chen, Haiqin; Chen, Yong Q; Chen, Wei; Song, Yuanda; Ratledge, Colin.

Microb Cell Fact ; 15: 35, 2016 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-26867592

4.

Role of malate transporter in lipid accumulation of oleaginous fungus Mucor circinelloides.

Zhao, Lina; Cánovas-Márquez, José T; Tang, Xin; Chen, Haiqin; Chen, Yong Q; Chen, Wei; Garre, Victoriano; Song, Yuanda; Ratledge, Colin.

Appl Microbiol Biotechnol ; 100(3): 1297-1305, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26512004

5.

Boosting fatty acid synthesis in Rhodococcus opacus PD630 by overexpression of autologous thioesterases.

Huang, Luxuan; Zhao, Lina; Zan, Xinyi; Song, Yuanda; Ratledge, Colin.

Biotechnol Lett ; 38(6): 999-1008, 2016 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-26956236

6.

The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems.

Ratledge, Colin.

Biotechnol Lett ; 36(8): 1557-68, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24752812

7.

Genetic engineering of Yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid.

Zhang, Baixi; Chen, Haiqin; Li, Min; Gu, Zhennan; Song, Yuanda; Ratledge, Colin; Chen, Yong Q; Zhang, Hao; Chen, Wei.

Microb Cell Fact ; 12: 70, 2013 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-23866108

8.

The time has come; good-bye to all this.

Ratledge, Colin.

Biotechnol Lett ; 40(1): 1-3, 2018 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-29143166

9.

Regulatory properties of malic enzyme in the oleaginous yeast, Yarrowia lipolytica, and its non-involvement in lipid accumulation.

Zhang, Huaiyuan; Zhang, Luning; Chen, Haiqin; Chen, Yong Q; Ratledge, Colin; Song, Yuanda; Chen, Wei.

Biotechnol Lett ; 35(12): 2091-8, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23892983

10.

Annotation and analysis of malic enzyme genes encoding for multiple isoforms in the fungus Mucor circinelloides CBS 277.49.

Vongsangnak, Wanwipa; Zhang, Yingtong; Chen, Wei; Ratledge, Colin; Song, Yuanda.

Biotechnol Lett ; 34(5): 941-7, 2012 May.

Artigo em Inglês | MEDLINE | ID: mdl-22367279

11.

Co-existence of type I fatty acid synthase and polyketide synthase metabolons in Aurantiochytrium SW1 and their implications for lipid biosynthesis.

Shuib, Shuwahida; Nazir, Mohamed Yusuf Mohamed; Ibrahim, Izyanti; Song, Yuanda; Ratledge, Colin; Hamid, Aidil Abdul.

Biochim Biophys Acta Mol Cell Biol Lipids ; 1867(12): 159224, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36007759

12.

First evidence for a multienzyme complex of lipid biosynthesis pathway enzymes in Cunninghamella bainieri.

Shuib, Shuwahida; Ibrahim, Izyanti; Mackeen, Mukram Mohamed; Ratledge, Colin; Hamid, Aidil Abdul.

Sci Rep ; 8(1): 3077, 2018 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-29449592

13.

Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestration.

Holmes, Margaret A; Paulsene, Wendy; Jide, Xu; Ratledge, Colin; Strong, Roland K.

Structure ; 13(1): 29-41, 2005 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-15642259

14.

Iron metabolism and infection.

Ratledge, Colin.

Food Nutr Bull ; 28(4 Suppl): S515-23, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-18297890

15.

The distinctiveness of ATP:citrate lyase from Aspergillus nidulans.

Adams, Ian P; Dack, Stephen; Dickinson, F Mark; Ratledge, Colin.

Biochim Biophys Acta ; 1597(1): 36-41, 2002 May 20.

Artigo em Inglês | MEDLINE | ID: mdl-12009400

16.

Complete Genome Sequence of a High Lipid-Producing Strain of Mucor circinelloides WJ11 and Comparative Genome Analysis with a Low Lipid-Producing Strain CBS 277.49.

Tang, Xin; Zhao, Lina; Chen, Haiqin; Chen, Yong Q; Chen, Wei; Song, Yuanda; Ratledge, Colin.

PLoS One ; 10(9): e0137543, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26352831

17.

Comparison of Biochemical Activities between High and Low Lipid-Producing Strains of Mucor circinelloides: An Explanation for the High Oleaginicity of Strain WJ11.

Tang, Xin; Chen, Haiqin; Chen, Yong Q; Chen, Wei; Garre, Victoriano; Song, Yuanda; Ratledge, Colin.

PLoS One ; 10(6): e0128396, 2015.

Artigo em Inglês | MEDLINE | ID: mdl-26046932

18.

Malic Enzyme is a Major Source of NADPH for Lipid Accumulation by Aspergillus Nidulans.

Wynn, James P; Ratledge, Colin.

Microbiology (Reading) ; 143(1): 253-257, 1997 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-33711851

19.

Fatty acid biosynthesis in microorganisms being used for Single Cell Oil production.

Ratledge, Colin.

Biochimie ; 86(11): 807-15, 2004 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-15589690

20.

Iron, mycobacteria and tuberculosis.

Ratledge, Colin.

Tuberculosis (Edinb) ; 84(1-2): 110-30, 2004.

Artigo em Inglês | MEDLINE | ID: mdl-14670352

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Improved Î³-linolenic acid production in Mucor circinelloides by homologous overexpressing of delta-12 and delta-6 desaturases.

Self-poisoning of Mycobacterium tuberculosis by interrupting siderophore recycling.

Proteomics analysis of high lipid-producing strain Mucor circinelloides WJ11: an explanation for the mechanism of lipid accumulation at the proteomic level.

Role of malate transporter in lipid accumulation of oleaginous fungus Mucor circinelloides.

Boosting fatty acid synthesis in Rhodococcus opacus PD630 by overexpression of autologous thioesterases.

The role of malic enzyme as the provider of NADPH in oleaginous microorganisms: a reappraisal and unsolved problems.

Genetic engineering of Yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid.

The time has come; good-bye to all this.

Regulatory properties of malic enzyme in the oleaginous yeast, Yarrowia lipolytica, and its non-involvement in lipid accumulation.

Annotation and analysis of malic enzyme genes encoding for multiple isoforms in the fungus Mucor circinelloides CBS 277.49.

Co-existence of type I fatty acid synthase and polyketide synthase metabolons in Aurantiochytrium SW1 and their implications for lipid biosynthesis.

First evidence for a multienzyme complex of lipid biosynthesis pathway enzymes in Cunninghamella bainieri.

Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestration.

Iron metabolism and infection.

The distinctiveness of ATP:citrate lyase from Aspergillus nidulans.

Complete Genome Sequence of a High Lipid-Producing Strain of Mucor circinelloides WJ11 and Comparative Genome Analysis with a Low Lipid-Producing Strain CBS 277.49.

Comparison of Biochemical Activities between High and Low Lipid-Producing Strains of Mucor circinelloides: An Explanation for the High Oleaginicity of Strain WJ11.

Malic Enzyme is a Major Source of NADPH for Lipid Accumulation by Aspergillus Nidulans.

Fatty acid biosynthesis in microorganisms being used for Single Cell Oil production.

Iron, mycobacteria and tuberculosis.