Detalhe da pesquisa
1.
Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding.
Nucleic Acids Res
; 51(3): 1173-1188, 2023 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36715327
2.
Predictive functional assay-based classification of PMS2 variants in Lynch syndrome.
Hum Mutat
; 43(9): 1249-1258, 2022 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451539
3.
Somatic POLE exonuclease domain mutations are early events in sporadic endometrial and colorectal carcinogenesis, determining driver mutational landscape, clonal neoantigen burden and immune response.
J Pathol
; 245(3): 283-296, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29604063
4.
CRISPR-Cas9 Causes Chromosomal Instability and Rearrangements in Cancer Cell Lines, Detectable by Cytogenetic Methods.
CRISPR J
; 2(6): 406-416, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31742432
5.
Adjuvant Treatment for POLE Proofreading Domain-Mutant Cancers: Sensitivity to Radiotherapy, Chemotherapy, and Nucleoside Analogues.
Clin Cancer Res
; 24(13): 3197-3203, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29559562
6.
A panoply of errors: polymerase proofreading domain mutations in cancer.
Nat Rev Cancer
; 16(2): 71-81, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26822575
7.
Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy.
Nat Commun
; 7: 11111, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27045317
8.
Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study.
Lancet Gastroenterol Hepatol
; 1(3): 207-216, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28404093