[Characteristics of energy metabolism and the effectiveness of muscular work in humans during adaptation to altitude]. / Osobennosti energoobmena i èffektivnosti myshechnoi raboty u cheloveka pri adaptatsii v gorakh.

The results obtained characterize changes in energy exchange and cardiovascular function that develop in exercising men in high mountains. At an early period of adaptation muscle performance decreased, indicating a new level of homeostatic regulation. The effectiveness of individual systems may differ from that of the whole body. Some of them (e. g., the cardiovascular system) may function very effectively, taking upon themselves additional functions. The final effect of adaptation to high mountains is an increase in the effectiveness of the whole body and an increase of aerobic reserves at sea level. Metabolic changes involve those that enhance lipid metabolism, including these that maintain active glycolysis. Structural rearrangements seem to be provided by a higher somatotropic activity of the hypothalamic-pituitary system.