Detalhe da pesquisa
1.
Alkylation of rabbit muscle creatine kinase surface methionine residues inhibits enzyme activity in vitro.
Arch Toxicol
; 95(10): 3253-3261, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34396457
2.
Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors.
Bioorg Med Chem
; 24(18): 4008-4015, 2016 09 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27377864
3.
Macrocyclic statine-based inhibitors of BACE-1.
Chembiochem
; 8(17): 2078-91, 2007 Nov 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-17963207
4.
Crystal structure of full length topoisomerase I from Thermotoga maritima.
J Mol Biol
; 358(5): 1328-40, 2006 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16600296
5.
Development of a simple and robust assay to screen for inhibitors of sphingosine kinases.
Assay Drug Dev Technol
; 5(2): 215-23, 2007 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-17477830
6.
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor.
J Med Chem
; 48(19): 5900-8, 2005 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-16161994
7.
A versatile high-throughput screen for inhibitors of lipid kinase activity: development of an immobilized phospholipid plate assay for phosphoinositide 3-kinase gamma.
J Biomol Screen
; 7(5): 441-50, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-14599360
8.
Unexpected active-site flexibility in the structure of human neutrophil elastase in complex with a new dihydropyrimidone inhibitor.
J Mol Biol
; 409(5): 681-91, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21549129
9.
Cinnabaramides A-G: analogues of lactacystin and salinosporamide from a terrestrial streptomycete.
J Nat Prod
; 70(2): 246-52, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17249727
10.
Targeted proteomics in biomarker validation: detection and quantification of proteins using a multi-dimensional peptide separation strategy.
Proteomics
; 6(10): 2947-58, 2006 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-16619308
11.
Development of a simple homogeneous assay to screen for inhibitors of N-acetylglucosamine-6-sulfotransferases.
Anal Biochem
; 315(1): 67-76, 2003 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-12672413