Detalhe da pesquisa
1.
Direct Automated MALDI Mass Spectrometry Analysis of Cellular Transporter Function: Inhibition of OATP2B1 Uptake by 294 Drugs.
Anal Chem
; 92(17): 11851-11859, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32867487
2.
Clinically Relevant OATP2B1 Inhibitors in Marketed Drug Space.
Mol Pharm
; 17(2): 488-498, 2020 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31834804
3.
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.
Nat Methods
; 12(12): 1129-31, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26524241
4.
Investigation of Janus Kinase (JAK) Inhibitors for Lung Delivery and the Importance of Aldehyde Oxidase Metabolism.
J Med Chem
; 65(1): 633-664, 2022 01 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34928601
5.
Optimization of Orally Bioavailable PI3Kδ Inhibitors and Identification of Vps34 as a Key Selectivity Target.
J Med Chem
; 63(2): 638-655, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31855425
6.
Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry.
Nat Protoc
; 10(10): 1567-93, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26379230
7.
Tracking cancer drugs in living cells by thermal profiling of the proteome.
Science
; 346(6205): 1255784, 2014 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25278616
8.
Working with small molecules: preparing and storing stock solutions and determination of kinetic solubility.
Methods Mol Biol
; 803: 265-71, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22065231
9.
A novel epsilon-cleavage within the transmembrane domain of the Alzheimer amyloid precursor protein demonstrates homology with Notch processing.
Biochemistry
; 41(8): 2825-35, 2002 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-11851430