Detalhe da pesquisa
1.
Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy.
Biochem J
; 476(3): 535-546, 2019 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30635359
2.
Identification of novel triazole inhibitors of Wnt/ß-catenin signaling based on the Niclosamide chemotype.
Bioorg Med Chem Lett
; 29(2): 317-321, 2019 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30551901
3.
Identification of DK419, a potent inhibitor of Wnt/ß-catenin signaling and colorectal cancer growth.
Bioorg Med Chem
; 26(20): 5435-5442, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30274939
4.
Benzimidazole inhibitors from the Niclosamide chemotype inhibit Wnt/ß-catenin signaling with selectivity over effects on ATP homeostasis.
Bioorg Med Chem
; 25(6): 1804-1816, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28233680
5.
Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth.
Breast Cancer Res
; 17: 20, 2015 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25849870
6.
Structure-activity studies of Wnt/ß-catenin inhibition in the Niclosamide chemotype: Identification of derivatives with improved drug exposure.
Bioorg Med Chem
; 23(17): 5829-38, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272032
7.
MARCKS and HSP70 interactions regulate mucin secretion by human airway epithelial cells in vitro.
Am J Physiol Lung Cell Mol Physiol
; 304(8): L511-8, 2013 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23377348
8.
Identification of select glucocorticoids as Smoothened agonists: potential utility for regenerative medicine.
Proc Natl Acad Sci U S A
; 107(20): 9323-8, 2010 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20439738
9.
Polyclonal HER2-specific antibodies induced by vaccination mediate receptor internalization and degradation in tumor cells.
Breast Cancer Res
; 14(3): R89, 2012 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22676470
10.
Phase 1 clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibition [corrected].
J Transl Med
; 10: 28, 2012 Feb 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-22325452
11.
Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells.
Hepatology
; 52(1): 278-90, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20578145
12.
Synergism from combined immunologic and pharmacologic inhibition of HER2 in vivo.
Int J Cancer
; 126(12): 2893-903, 2010 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19856307
13.
The anti-helminthic niclosamide inhibits Wnt/Frizzled1 signaling.
Biochemistry
; 48(43): 10267-74, 2009 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-19772353
14.
Tyrosine phosphorylation of netrin receptors in netrin-1 signaling.
Neurosignals
; 16(2-3): 235-45, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18253061
15.
Focal adhesion kinase in netrin-1 signaling.
Nat Neurosci
; 7(11): 1204-12, 2004 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-15494733
16.
Niclosamide-conjugated polypeptide nanoparticles inhibit Wnt signaling and colon cancer growth.
Nanoscale
; 9(34): 12709-12717, 2017 Aug 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-28828438
17.
Regulation of hedgehog signaling by Myc-interacting zinc finger protein 1, Miz1.
PLoS One
; 8(5): e63353, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23671675
18.
{beta}-Arrestin-2 Mediates Anti-apoptotic Signaling through Regulation of BAD Phosphorylation.
J Biol Chem
; 284(13): 8855-65, 2009 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19171933
19.
G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer.
J Biol Chem
; 281(29): 20577-88, 2006 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16687412
20.
DCC-dependent phospholipase C signaling in netrin-1-induced neurite elongation.
J Biol Chem
; 281(5): 2605-11, 2006 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-16321979