Detalhe da pesquisa
1.
From target discovery to clinical drug development with human genetics.
Nature
; 620(7975): 737-745, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37612393
2.
Metabolomic pattern associated with physical sequelae in patients presenting with respiratory symptoms validates the aestivation concept in dehydrated patients.
Physiol Genomics
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38738317
3.
Genetic architecture: the shape of the genetic contribution to human traits and disease.
Nat Rev Genet
; 19(2): 110-124, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29225335
4.
Predicting ExWAS findings from GWAS data: a shorter path to causal genes.
Hum Genet
; 142(6): 749-758, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-37009933
5.
Colocalization of expression transcripts with COVID-19 outcomes is rare across cell states, cell types and organs.
Hum Genet
; 142(10): 1461-1476, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37640912
6.
Genome-wide Association Study for Vitamin D Levels Reveals 69 Independent Loci.
Am J Hum Genet
; 106(3): 327-337, 2020 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32059762
7.
Little evidence for an effect of smoking on multiple sclerosis risk: A Mendelian Randomization study.
PLoS Biol
; 18(11): e3000973, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33253141
8.
Colocalization of Gene Expression and DNA Methylation with Genetic Risk Variants Supports Functional Roles of MUC5B and DSP in Idiopathic Pulmonary Fibrosis.
Am J Respir Crit Care Med
; 206(10): 1259-1270, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35816432
9.
Block coordinate descent algorithm improves variable selection and estimation in error-in-variables regression.
Genet Epidemiol
; 45(8): 874-890, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34468045
10.
An effector index to predict target genes at GWAS loci.
Hum Genet
; 141(8): 1431-1447, 2022 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-35147782
11.
Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study.
Eur Respir J
; 59(2)2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34172473
12.
Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease.
Blood
; 136(5): 533-541, 2020 07 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32457982
13.
Dehydration is associated with production of organic osmolytes and predicts physical long-term symptoms after COVID-19: a multicenter cohort study.
Crit Care
; 26(1): 322, 2022 10 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36271419
14.
Correction: Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study.
PLoS Med
; 18(4): e1003624, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914743
15.
Vitamin D levels and risk of type 1 diabetes: A Mendelian randomization study.
PLoS Med
; 18(2): e1003536, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33630834
16.
Vitamin D and COVID-19 susceptibility and severity in the COVID-19 Host Genetics Initiative: A Mendelian randomization study.
PLoS Med
; 18(6): e1003605, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34061844
17.
Life-Course Genome-wide Association Study Meta-analysis of Total Body BMD and Assessment of Age-Specific Effects.
Am J Hum Genet
; 102(1): 88-102, 2018 01 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29304378
18.
Genotype imputation and reference panel: a systematic evaluation on haplotype size and diversity.
Brief Bioinform
; 2019 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32002535
19.
Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening.
Genet Med
; 23(3): 508-515, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33110269
20.
Childhood obesity and multiple sclerosis: A Mendelian randomization study.
Mult Scler
; 27(14): 2150-2158, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33749377