Detalhe da pesquisa
1.
Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis.
Carcinogenesis
; 36(7): 769-81, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25939751
2.
The combination of the histone deacetylase inhibitor vorinostat and synthetic triterpenoids reduces tumorigenesis in mouse models of cancer.
Carcinogenesis
; 34(1): 199-210, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23042302
3.
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Clin Cancer Res
; 14(14): 4556-63, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18628471
4.
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Cancer Res
; 67(6): 2414-9, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17363558
5.
The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.
Mol Cancer Ther
; 7(5): 1251-7, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483313
6.
A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland.
Clin Cancer Res
; 13(20): 6237-43, 2007 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17947492
7.
Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities.
Mol Cancer Ther
; 6(7): 2113-9, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17620440
8.
The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.
Clin Cancer Res
; 12(14 Pt 1): 4288-93, 2006 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16857804
9.
The combination of the rexinoid, LG100268, and a selective estrogen receptor modulator, either arzoxifene or acolbifene, synergizes in the prevention and treatment of mammary tumors in an estrogen receptor-negative model of breast cancer.
Clin Cancer Res
; 12(19): 5902-9, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17020999
10.
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
Cancer Res
; 65(11): 4789-98, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15930299
11.
The selective estrogen receptor modulator arzoxifene and the rexinoid LG100268 cooperate to promote transforming growth factor beta-dependent apoptosis in breast cancer.
Cancer Res
; 64(10): 3566-71, 2004 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-15150113
12.
Synthetic triterpenoids enhance transforming growth factor beta/Smad signaling.
Cancer Res
; 63(6): 1371-6, 2003 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12649201
13.
The Rexinoids LG100268 and LG101506 Inhibit Inflammation and Suppress Lung Carcinogenesis in A/J Mice.
Cancer Prev Res (Phila)
; 9(1): 105-14, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26554632
14.
The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
Clin Cancer Res
; 9(7): 2798-806, 2003 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-12855660
15.
Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268.
Clin Cancer Res
; 8(10): 3270-5, 2002 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-12374698
16.
Design and synthesis of tricyclic compounds with enone functionalities in rings A and C: a novel class of highly active inhibitors of nitric oxide production in mouse macrophages.
J Med Chem
; 45(22): 4801-5, 2002 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-12383005
17.
The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient mice.
Cancer Prev Res (Phila)
; 7(7): 698-707, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24817481
18.
The synthetic triterpenoid CDDO-methyl ester delays estrogen receptor-negative mammary carcinogenesis in polyoma middle T mice.
Cancer Prev Res (Phila)
; 5(5): 726-34, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22401982
19.
CDDO-methyl ester delays breast cancer development in BRCA1-mutated mice.
Cancer Prev Res (Phila)
; 5(1): 89-97, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21933912
20.
Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis.
Free Radic Biol Med
; 51(1): 88-96, 2011 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21457778