Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Report of the First ONTOX Stakeholder Network Meeting: Digging Under the Surface of ONTOX Together With the Stakeholders.

Diemar, Michael G; Vinken, Mathieu; Teunis, Marc; Krul, Cyrille A M; Busquet, Francois; Zajac, Julia Dominika; Kandarova, Helena; Corvi, Raffaella; Rosso, Matteo Z; Kharina, Anastasiia; Bryndum, Louise Stab; Santillo, Michael; Bloch, Denise; Kucheryavenko, Olena; Panagiotakos, Demosthenes; Rogiers, Vera; Beekhuijzen, Manon; Giusti, Arianna; Najjar, Abdulkarim; Courage, Carol; Koenig, Torben; Kolle, Susanne; Boonen, Harrie; Dhalluin, Stephane; Boberg, Julie; Müller, Boris P; Kukic, Predrag; Ritskes-Hoitinga, Merel; Grasselli, Elena; Zietek, Tamara; Stoddart, Gilly; Heusinkveld, Harm J; Castell, Jose V; Benfenati, Emilio; Yang, Huan; Perera, Simón; Paini, Alicia; Kramer, Nynke I; Hartung, Thomas; Janssen, Manoe; Fritsche, Ellen; Jennen, Danyel G J; Piumatti, Matteo; Rathman, James; Marusczyk, Jörg; Milec, Lucia; Roggen, Erwin L.

Altern Lab Anim ; 52(2): 117-131, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38235727

2.

Recommendations for robust and reproducible preclinical research in personalised medicine.

Fosse, Vibeke; Oldoni, Emanuela; Bietrix, Florence; Budillon, Alfredo; Daskalopoulos, Evangelos P; Fratelli, Maddalena; Gerlach, Björn; Groenen, Peter M A; Hölter, Sabine M; Menon, Julia M L; Mobasheri, Ali; Osborne, Nikki; Ritskes-Hoitinga, Merel; Ryll, Bettina; Schmitt, Elmar; Ussi, Anton; Andreu, Antonio L; McCormack, Emmet.

BMC Med ; 21(1): 14, 2023 01 08.

Artigo em Inglês | MEDLINE | ID: mdl-36617553

3.

Medical regulators: look beyond animal tests.

Ritskes-Hoitinga, Merel.

Nature ; 604(7907): 599, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35478231

4.

The 3Ranker: An AI-based Algorithm for Finding Non-animal Alternative Methods.

van Beuningen, Niels; Alkema, Sinne; Hijlkema, Nils; Ulfhake, Brun; Frias, Rafael; Ritskes-Hoitinga, Merel; Alkema, Wynand.

Altern Lab Anim ; 51(6): 376-386, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37864460

5.

A History of Regulatory Animal Testing: What Can We Learn?

Swaters, Doortje; van Veen, Anne; van Meurs, Wim; Turner, Janette Ellen; Ritskes-Hoitinga, Merel.

Altern Lab Anim ; 50(5): 322-329, 2022 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-35983829

6.

Effects of sleep deprivation on maternal behaviour in animal models: A systematic review and meta-analysis.

Pires, Gabriel N; Oliveira, Thainá B; Mello, Victoria F F; Bezerra, Andréia G; Leenaars, Cathalijn H C; Ritskes-Hoitinga, Merel; Tufik, Sergio; Andersen, Monica L.

J Sleep Res ; 30(5): e13333, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-33719116

7.

A health-based recommended occupational exposure limit for nitrous oxide using experimental animal data based on a systematic review and dose-response analysis.

Menon, Julia M L; van Luijk, Judith A K R; Swinkels, Janne; Lukas, Eva; Ritskes-Hoitinga, Merel; Roeleveld, Nel; Schlünssen, Vivi; Mandrioli, Daniele; Hoffmann, Sebastian; Popa, Madalina; Scheepers, Paul T J.

Environ Res ; 201: 111575, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-34174259

8.

Can prospective systematic reviews of animal studies improve clinical translation?

Pound, Pandora; Ritskes-Hoitinga, Merel.

J Transl Med ; 18(1): 15, 2020 01 09.

Artigo em Inglês | MEDLINE | ID: mdl-31918734

9.

The evidence for the physiological effects of lactate on the cerebral microcirculation: a systematic review.

Hollyer, Tristan R; Bordoni, Luca; Kousholt, Birgitte S; van Luijk, Judith; Ritskes-Hoitinga, Merel; Østergaard, Leif.

J Neurochem ; 148(6): 712-730, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30472728

10.

Animal to human translation: a systematic scoping review of reported concordance rates.

Leenaars, Cathalijn H C; Kouwenaar, Carien; Stafleu, Frans R; Bleich, André; Ritskes-Hoitinga, Merel; De Vries, Rob B M; Meijboom, Franck L B.

J Transl Med ; 17(1): 223, 2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31307492

11.

Establishing a health-based recommended occupational exposure limit for nitrous oxide using experimental animal data - A systematic review protocol.

van Luijk, Judith A K R; Popa, Madalina; Swinkels, Janne; Menon, Julia M L; Alkema, Wynand; Roeleveld, Nel; Hoffmann, Sebastian E; Schlünssen, Vivi; Mandrioli, Daniele; Ritskes-Hoitinga, Merel; Scheepers, Paul T J.

Environ Res ; 178: 108711, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31520819

12.

Is it possible to overcome issues of external validity in preclinical animal research? Why most animal models are bound to fail.

Pound, Pandora; Ritskes-Hoitinga, Merel.

J Transl Med ; 16(1): 304, 2018 11 07.

Artigo em Inglês | MEDLINE | ID: mdl-30404629

13.

Letter to the editor - round table unites to tackle culture change in an effort to improve animal research reporting.

Osborne, Nicola J; Ritskes-Hoitinga, Merel; Ahluwahlia, Amrita; Alam, Sabina; Brown, Matthew; Henderson, Hayley; de Leeuw, Wim; Marsh, Joan; Moher, David; van Oort, Erica; Rawle, Frances; Riederer, Beat M; Sanchez-Morgado, Jose; Sena, Emily S; Struthers, Caroline; Westmore, Matthew; Avey, Marc T; Kalman, Rony; O'Connor, Annette; Sargeant, Jan; Petrie, Anja; Smith, Adrian.

BMC Vet Res ; 13(1): 314, 2017 Nov 07.

Artigo em Inglês | MEDLINE | ID: mdl-29115951

14.

The Use of Artificial Intelligence for the Fast and Effective Identification of Three Rs-based Literature.

Ritskes-Hoitinga, Merel; Alkema, Wynand.

Altern Lab Anim ; 49(4): 133-136, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-34581190

15.

Improving animal research reporting standards: HARRP, the first step of a unified approach by ICLAS to improve animal research reporting standards worldwide.

Osborne, Nikki; Avey, Marc T; Anestidou, Lida; Ritskes-Hoitinga, Merel; Griffin, Gilly.

EMBO Rep ; 19(5)2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29669797

16.

SYRCLE's risk of bias tool for animal studies.

Hooijmans, Carlijn R; Rovers, Maroeska M; de Vries, Rob B M; Leenaars, Marlies; Ritskes-Hoitinga, Merel; Langendam, Miranda W.

BMC Med Res Methodol ; 14: 43, 2014 Mar 26.

Artigo em Inglês | MEDLINE | ID: mdl-24667063

17.

Pollutant exposure and myocardial injury: Protocol and progress report for a toxicological systematic mapping review.

Roos, Tom; Leenaars, Cathalijn; Schaffert, Alexandra; Paparella, Martin; Murugadoss, Sivakumar; Mertens, Birgit; Linzalone, Nunzia; Donzelli, Gabriele; Ritskes-Hoitinga, Merel; Gehring, Ronette.

ALTEX ; 41(2): 248-259, 2024.

Artigo em Inglês | MEDLINE | ID: mdl-37983382

18.

Methodological quality assessment should move beyond design specificity.

Stone, Jennifer C; Glass, Kathryn; Ritskes-Hoitinga, Merel; Munn, Zachary; Tugwell, Peter; Doi, Suhail A R.

JBI Evid Synth ; 21(3): 507-519, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36683451

19.

Comparing translational success rates across medical research fields - A combined analysis of literature and clinical trial data.

Van de Wall, Gwen; Van Hattem, Astrid; Timmermans, Joy; Ritskes-Hoitinga, Merel; Bleich, André; Leenaars, Cathalijn.

ALTEX ; 40(4): 584-594, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37158378

20.

Reporting of 3Rs Approaches in Preclinical Animal Experimental Studies-A Nationwide Study.

Kousholt, Birgitte S; Præstegaard, Kirstine F; Stone, Jennifer C; Thomsen, Anders F; Johansen, Thea T; Ritskes-Hoitinga, Merel; Wegener, Gregers.

Animals (Basel) ; 13(19)2023 Sep 23.

Artigo em Inglês | MEDLINE | ID: mdl-37835611

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