RESUMO
Herpes simplex virus infection in immunocompromised individuals, including AIDS patients, is characterized by its tendency for atypical presentations and unusual locations, often resulting in delayed diagnosis and treatment. Three HIV-infected patients who developed prolonged cutaneous lesions of the fingers are presented. These lesions were unmodified by previous antibiotic treatment, and rapidly progressed to the complete destruction of nail structures in two patients. Viral culture confirmed the diagnosis of herpetic whitlow in all cases, and treatment with oral acyclovir resulted in complete recovery. Surgical treatment was not necessary.
Assuntos
Infecções Oportunistas Relacionadas com a AIDS/complicações , Dermatoses da Mão/virologia , Herpes Simples/virologia , Infecções Oportunistas Relacionadas com a AIDS/tratamento farmacológico , Aciclovir/uso terapêutico , Adulto , Antivirais/uso terapêutico , Feminino , Dedos , Dermatoses da Mão/tratamento farmacológico , Herpes Simples/tratamento farmacológico , Humanos , MasculinoRESUMO
Immunosuppression is a well-documented precipitant of porokeratosis (PK). However, PK is not considered among the most common cutaneous disorders in immunosuppressed patients. We studied prospectively a series of 103 renal transplant patients and found 11 cases (10.68%) of PK. Our series represents the highest incidence of PK in transplant patients reported so far. Our findings suggest that PK in transplant recipients may be more frequent than previously thought.