Detalhe da pesquisa
1.
Phenotypic heterogeneity and evolution of melanoma cells associated with targeted therapy resistance.
PLoS Comput Biol
; 15(6): e1007034, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31166947
2.
PD-1 blockade induces responses by inhibiting adaptive immune resistance.
Nature
; 515(7528): 568-71, 2014 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25428505
3.
Combining targeted therapy with immunotherapy. Can 1+1 equal more than 2?
Semin Immunol
; 28(1): 73-80, 2016 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26861544
4.
Single-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistance.
Proc Natl Acad Sci U S A
; 114(52): 13679-13684, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29229836
5.
MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells.
Proc Natl Acad Sci U S A
; 112(5): E420-9, 2015 Feb 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25605940
6.
RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.
N Engl J Med
; 366(3): 207-15, 2012 Jan 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-22256804
7.
Effects of AKT inhibitor therapy in response and resistance to BRAF inhibition in melanoma.
Mol Cancer
; 13: 83, 2014 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-24735930
8.
Antitumor activity of the ERK inhibitor SCH772984 [corrected] against BRAF mutant, NRAS mutant and wild-type melanoma.
Mol Cancer
; 13: 194, 2014 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25142146
9.
Lytic lesions in a patient with past history of renal cancer.
Arch Esp Urol
; 66(3): 302-4, 2013 Apr.
Artigo
em Inglês, Espanhol
| MEDLINE | ID: mdl-23648750
10.
Erratum to: Antitumor activity of the ERK inhibitor SCH722984 against BRAF mutant, NRAS mutant and wild-type melanoma.
Mol Cancer
; 14: 128, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26134498
11.
Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line.
Nat Commun
; 11(1): 2345, 2020 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393797
12.
Immunotherapy Resistance by Inflammation-Induced Dedifferentiation.
Cancer Discov
; 8(8): 935-943, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29899062
13.
Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress.
Cancer Cell
; 33(5): 890-904.e5, 2018 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29657129
14.
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors.
JCI Insight
; 3(4)2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29467321
15.
MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor.
Oncotarget
; 8(11): 17795-17809, 2017 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28147313
16.
Response to Programmed Cell Death-1 Blockade in a Murine Melanoma Syngeneic Model Requires Costimulation, CD4, and CD8 T Cells.
Cancer Immunol Res
; 4(10): 845-857, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27589875
17.
Anti-PD-1 therapy in melanoma.
Semin Oncol
; 42(3): 466-73, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-25965365
18.
Improved antitumor activity of immunotherapy with BRAF and MEK inhibitors in BRAF(V600E) melanoma.
Sci Transl Med
; 7(279): 279ra41, 2015 Mar 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25787767
19.
Combining targeted therapy with immunotherapy in BRAF-mutant melanoma: promise and challenges.
J Clin Oncol
; 32(21): 2248-54, 2014 Jul 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24958825
20.
Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy.
Cancer Res
; 74(1): 153-161, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24247719