Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Abiraterone acetate plus prednisolone with or without enzalutamide for patients with metastatic prostate cancer starting androgen deprivation therapy: final results from two randomised phase 3 trials of the STAMPEDE platform protocol.

Attard, Gerhardt; Murphy, Laura; Clarke, Noel W; Sachdeva, Ashwin; Jones, Craig; Hoyle, Alex; Cross, William; Jones, Robert J; Parker, Christopher C; Gillessen, Silke; Cook, Adrian; Brawley, Chris; Gilson, Clare; Rush, Hannah; Abdel-Aty, Hoda; Amos, Claire L; Murphy, Claire; Chowdhury, Simon; Malik, Zafar; Russell, J Martin; Parkar, Nazia; Pugh, Cheryl; Diaz-Montana, Carlos; Pezaro, Carmel; Grant, Warren; Saxby, Helen; Pedley, Ian; O'Sullivan, Joe M; Birtle, Alison; Gale, Joanna; Srihari, Narayanan; Thomas, Carys; Tanguay, Jacob; Wagstaff, John; Das, Prantik; Gray, Emma; Alzouebi, Mymoona; Parikh, Omi; Robinson, Angus; Montazeri, Amir H; Wylie, James; Zarkar, Anjali; Cathomas, Richard; Brown, Michael D; Jain, Yatin; Dearnaley, David P; Mason, Malcolm D; Gilbert, Duncan; Langley, Ruth E; Millman, Robin.

Lancet Oncol ; 24(5): 443-456, 2023 05.

Artigo em Inglês | MEDLINE | ID: mdl-37142371

2.

Abiraterone acetate and prednisolone with or without enzalutamide for high-risk non-metastatic prostate cancer: a meta-analysis of primary results from two randomised controlled phase 3 trials of the STAMPEDE platform protocol.

Attard, Gerhardt; Murphy, Laura; Clarke, Noel W; Cross, William; Jones, Robert J; Parker, Christopher C; Gillessen, Silke; Cook, Adrian; Brawley, Chris; Amos, Claire L; Atako, Nafisah; Pugh, Cheryl; Buckner, Michelle; Chowdhury, Simon; Malik, Zafar; Russell, J Martin; Gilson, Clare; Rush, Hannah; Bowen, Jo; Lydon, Anna; Pedley, Ian; O'Sullivan, Joe M; Birtle, Alison; Gale, Joanna; Srihari, Narayanan; Thomas, Carys; Tanguay, Jacob; Wagstaff, John; Das, Prantik; Gray, Emma; Alzoueb, Mymoona; Parikh, Omi; Robinson, Angus; Syndikus, Isabel; Wylie, James; Zarkar, Anjali; Thalmann, George; de Bono, Johann S; Dearnaley, David P; Mason, Malcolm D; Gilbert, Duncan; Langley, Ruth E; Millman, Robin; Matheson, David; Sydes, Matthew R; Brown, Louise C; Parmar, Mahesh K B; James, Nicholas D.

Lancet ; 399(10323): 447-460, 2022 01 29.

Artigo em Inglês | MEDLINE | ID: mdl-34953525

3.

Observation versus screening spinal MRI and pre-emptive treatment for spinal cord compression in patients with castration-resistant prostate cancer and spinal metastases in the UK (PROMPTS): an open-label, randomised, controlled, phase 3 trial.

Dearnaley, David; Hinder, Victoria; Hijab, Adham; Horan, Gail; Srihari, Narayanan; Rich, Philip; Houston, J Graeme; Henry, Ann M; Gibbs, Stephanie; Venkitaraman, Ram; Cruickshank, Clare; Hassan, Shama; Miners, Alec; Mason, Malcolm; Pedley, Ian; Payne, Heather; Brock, Susannah; Wade, Robert; Robinson, Angus; Din, Omar; Lees, Kathryn; Graham, John; Worlding, Jane; Murray, Julia; Parker, Chris; Griffin, Clare; Sohaib, Aslam; Hall, Emma.

Lancet Oncol ; 23(4): 501-513, 2022 04.

Artigo em Inglês | MEDLINE | ID: mdl-35279270

4.

A European, prospective, observational study of enzalutamide in patients with metastatic castration-resistant prostate cancer: PREMISE.

Payne, Heather; Robinson, Angus; Rappe, Bernard; Hilman, Serena; De Giorgi, Ugo; Joniau, Steven; Bordonaro, Roberto; Mallick, Stéphane; Dourthe, Louis-Marie; Flores, Moisés Mira; Gumà, Josep; Baron, Benoit; Duran, Aurea; Pranzo, Alessandra; Serikoff, Alexis; Mott, David; Herdman, Mike; Pavesi, Marco; De Santis, Maria.

Int J Cancer ; 150(5): 837-846, 2022 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-34648657

5.

Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5-year follow-up results from the STAMPEDE randomised trial (NCT00268476).

James, Nicholas D; Clarke, Noel W; Cook, Adrian; Ali, Adnan; Hoyle, Alex P; Attard, Gerhardt; Brawley, Christopher D; Chowdhury, Simon; Cross, William R; Dearnaley, David P; de Bono, Johann S; Diaz-Montana, Carlos; Gilbert, Duncan; Gillessen, Silke; Gilson, Clare; Jones, Rob J; Langley, Ruth E; Malik, Zafar I; Matheson, David J; Millman, Robin; Parker, Chris C; Pugh, Cheryl; Rush, Hannah; Russell, J Martin; Berthold, Dominik R; Buckner, Michelle L; Mason, Malcolm D; Ritchie, Alastair W S; Birtle, Alison J; Brock, Susannah J; Das, Prantik; Ford, Dan; Gale, Joanna; Grant, Warren; Gray, Emma K; Hoskin, Peter; Khan, Mohammad M; Manetta, Caroline; McPhail, Neil J; O'Sullivan, Joe M; Parikh, Omi; Perna, Carla; Pezaro, Carmel J; Protheroe, Andrew S; Robinson, Angus J; Rudman, Sarah M; Sheehan, Denise J; Srihari, Narayanan N; Syndikus, Isabel; Tanguay, Jacob S.

Int J Cancer ; 151(3): 422-434, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-35411939

6.

Transdermal oestradiol for androgen suppression in prostate cancer: long-term cardiovascular outcomes from the randomised Prostate Adenocarcinoma Transcutaneous Hormone (PATCH) trial programme.

Langley, Ruth E; Gilbert, Duncan C; Duong, Trinh; Clarke, Noel W; Nankivell, Matthew; Rosen, Stuart D; Mangar, Stephen; Macnair, Archie; Sundaram, Subramanian Kanaga; Laniado, Marc E; Dixit, Sanjay; Madaan, Sanjeev; Manetta, Caroline; Pope, Alvan; Scrase, Christopher D; Mckay, Stephen; Muazzam, Iqtedar A; Collins, Gerald N; Worlding, Jane; Williams, Simon T; Paez, Edgar; Robinson, Angus; McFarlane, Jonathan; Deighan, John V; Marshall, John; Forcat, Silvia; Weiss, Melanie; Kockelbergh, Roger; Alhasso, Abdulla; Kynaston, Howard; Parmar, Mahesh.

Lancet ; 397(10274): 581-591, 2021 02 13.

Artigo em Inglês | MEDLINE | ID: mdl-33581820

7.

Long-term multicentre experience of adjuvant radiotherapy for pN3 squamous cell carcinoma of the penis.

Ager, Michael; Njoku, Kelechi; Serra, Maria; Robinson, Angus; Pickering, Lisa; Afshar, Mehran; Vyas, Lona; Eardley, Ian; Kayes, Oliver; Elmamoun, Mamoun; Khoo, Vincent; Ayres, Benjamin; Henry, Ann; Watkin, Nick; Tree, Alison C.

BJU Int ; 128(4): 451-459, 2021 10.

Artigo em Inglês | MEDLINE | ID: mdl-33249744

8.

Olaparib in patients with metastatic castration-resistant prostate cancer with DNA repair gene aberrations (TOPARP-B): a multicentre, open-label, randomised, phase 2 trial.

Mateo, Joaquin; Porta, Nuria; Bianchini, Diletta; McGovern, Ursula; Elliott, Tony; Jones, Robert; Syndikus, Isabel; Ralph, Christy; Jain, Suneil; Varughese, Mohini; Parikh, Omi; Crabb, Simon; Robinson, Angus; McLaren, Duncan; Birtle, Alison; Tanguay, Jacob; Miranda, Susana; Figueiredo, Ines; Seed, George; Bertan, Claudia; Flohr, Penny; Ebbs, Berni; Rescigno, Pasquale; Fowler, Gemma; Ferreira, Ana; Riisnaes, Ruth; Pereira, Rita; Curcean, Andra; Chandler, Robert; Clarke, Matthew; Gurel, Bora; Crespo, Mateus; Nava Rodrigues, Daniel; Sandhu, Shahneen; Espinasse, Aude; Chatfield, Peter; Tunariu, Nina; Yuan, Wei; Hall, Emma; Carreira, Suzanne; de Bono, Johann S.

Lancet Oncol ; 21(1): 162-174, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31806540

9.

Abiraterone for Prostate Cancer Not Previously Treated with Hormone Therapy.

James, Nicholas D; de Bono, Johann S; Spears, Melissa R; Clarke, Noel W; Mason, Malcolm D; Dearnaley, David P; Ritchie, Alastair W S; Amos, Claire L; Gilson, Clare; Jones, Rob J; Matheson, David; Millman, Robin; Attard, Gerhardt; Chowdhury, Simon; Cross, William R; Gillessen, Silke; Parker, Christopher C; Russell, J Martin; Berthold, Dominik R; Brawley, Chris; Adab, Fawzi; Aung, San; Birtle, Alison J; Bowen, Jo; Brock, Susannah; Chakraborti, Prabir; Ferguson, Catherine; Gale, Joanna; Gray, Emma; Hingorani, Mohan; Hoskin, Peter J; Lester, Jason F; Malik, Zafar I; McKinna, Fiona; McPhail, Neil; Money-Kyrle, Julian; O'Sullivan, Joe; Parikh, Omi; Protheroe, Andrew; Robinson, Angus; Srihari, Narayanan N; Thomas, Carys; Wagstaff, John; Wylie, James; Zarkar, Anjali; Parmar, Mahesh K B; Sydes, Matthew R.

N Engl J Med ; 377(4): 338-351, 2017 07 27.

Artigo em Inglês | MEDLINE | ID: mdl-28578639

10.

²²³Ra-Dichloride in castration-resistant metastatic prostate cancer: improving outcomes and identifying predictors of survival in clinical practice.

Dizdarevic, Sabina; Jessop, Maryam; Begley, Patrick; Main, Sean; Robinson, Angus.

Eur J Nucl Med Mol Imaging ; 45(13): 2264-2273, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-29998419

11.

Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial.

James, Nicholas D; Sydes, Matthew R; Clarke, Noel W; Mason, Malcolm D; Dearnaley, David P; Spears, Melissa R; Ritchie, Alastair W S; Parker, Christopher C; Russell, J Martin; Attard, Gerhardt; de Bono, Johann; Cross, William; Jones, Rob J; Thalmann, George; Amos, Claire; Matheson, David; Millman, Robin; Alzouebi, Mymoona; Beesley, Sharon; Birtle, Alison J; Brock, Susannah; Cathomas, Richard; Chakraborti, Prabir; Chowdhury, Simon; Cook, Audrey; Elliott, Tony; Gale, Joanna; Gibbs, Stephanie; Graham, John D; Hetherington, John; Hughes, Robert; Laing, Robert; McKinna, Fiona; McLaren, Duncan B; O'Sullivan, Joe M; Parikh, Omi; Peedell, Clive; Protheroe, Andrew; Robinson, Angus J; Srihari, Narayanan; Srinivasan, Rajaguru; Staffurth, John; Sundar, Santhanam; Tolan, Shaun; Tsang, David; Wagstaff, John; Parmar, Mahesh K B.

Lancet ; 387(10024): 1163-77, 2016 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-26719232

12.

Gemcitabine and capecitabine with or without telomerase peptide vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer (TeloVac): an open-label, randomised, phase 3 trial.

Middleton, Gary; Silcocks, Paul; Cox, Trevor; Valle, Juan; Wadsley, Jonathan; Propper, David; Coxon, Fareeda; Ross, Paul; Madhusudan, Srinivasan; Roques, Tom; Cunningham, David; Falk, Stephen; Wadd, Nick; Harrison, Mark; Corrie, Pippa; Iveson, Tim; Robinson, Angus; McAdam, Karen; Eatock, Martin; Evans, Jeff; Archer, Caroline; Hickish, Tamas; Garcia-Alonso, Angel; Nicolson, Marianne; Steward, William; Anthoney, Alan; Greenhalf, William; Shaw, Victoria; Costello, Eithne; Naisbitt, Dean; Rawcliffe, Charlotte; Nanson, Gemma; Neoptolemos, John.

Lancet Oncol ; 15(8): 829-40, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24954781

13.

Metastatic prostate cancer men's attitudes towards treatment of the local tumour and metastasis evaluative research (IP5-MATTER): protocol for a prospective, multicentre discrete choice experiment study.

Connor, Martin John; Genie, Mesfin G; Gonzalez, Michael; Sarwar, Naveed; Thippu Jayaprakash, Kamalram; Horan, Gail; Hosking-Jervis, Feargus; Klimowska-Nassar, Natalia; Sukumar, Johanna; Pokrovska, Tzveta; Basak, Dolan; Robinson, Angus; Beresford, Mark; Rai, Bhavan; Mangar, Stephen; Khoo, Vincent; Dudderidge, Tim; Falconer, Alison; Winkler, Mathias; Watson, Verity; Ahmed, Hashim Uddin.

BMJ Open ; 11(11): e048996, 2021 11 18.

Artigo em Inglês | MEDLINE | ID: mdl-34794989

14.

Pan-AKT Inhibitor Capivasertib With Docetaxel and Prednisolone in Metastatic Castration-Resistant Prostate Cancer: A Randomized, Placebo-Controlled Phase II Trial (ProCAID).

Crabb, Simon J; Griffiths, Gareth; Marwood, Ellice; Dunkley, Denise; Downs, Nichola; Martin, Karen; Light, Michelle; Northey, Josh; Wilding, Sam; Whitehead, Amy; Shaw, Emily; Birtle, Alison J; Bahl, Amit; Elliott, Tony; Westbury, Charlotte; Sundar, Santhanam; Robinson, Angus; Jagdev, Satinder; Kumar, Satish; Rooney, Claire; Salinas-Souza, Carolina; Stephens, Christine; Khoo, Vincent; Jones, Robert J.

J Clin Oncol ; 39(3): 190-201, 2021 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-33326257

15.

Addition of Docetaxel to First-line Long-term Hormone Therapy in Prostate Cancer (STAMPEDE): Modelling to Estimate Long-term Survival, Quality-adjusted Survival, and Cost-effectiveness.

Woods, Beth S; Sideris, Eleftherios; Sydes, Matthew R; Gannon, Melissa R; Parmar, Mahesh K B; Alzouebi, Mymoona; Attard, Gerhardt; Birtle, Alison J; Brock, Susannah; Cathomas, Richard; Chakraborti, Prabir R; Cook, Audrey; Cross, William R; Dearnaley, David P; Gale, Joanna; Gibbs, Stephanie; Graham, John D; Hughes, Robert; Jones, Rob J; Laing, Robert; Mason, Malcolm D; Matheson, David; McLaren, Duncan B; Millman, Robin; O'Sullivan, Joe M; Parikh, Omi; Parker, Christopher C; Peedell, Clive; Protheroe, Andrew; Ritchie, Alastair W S; Robinson, Angus; Russell, J Martin; Simms, Matthew S; Srihari, Narayanan N; Srinivasan, Rajaguru; Staffurth, John N; Sundar, Santhanam; Thalmann, George N; Tolan, Shaun; Tran, Anna T H; Tsang, David; Wagstaff, John; James, Nicholas D; Sculpher, Mark J.

Eur Urol Oncol ; 1(6): 449-458, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-31158087

16.

A Randomised Phase 2 Study of AZD2014 Versus Everolimus in Patients with VEGF-Refractory Metastatic Clear Cell Renal Cancer.

Powles, Thomas; Wheater, Matthew; Din, Omar; Geldart, Thomas; Boleti, Ekaterini; Stockdale, Andrew; Sundar, Santhanam; Robinson, Angus; Ahmed, Imtiaz; Wimalasingham, Akhila; Burke, Wendy; Sarker, Shah-Jalal; Hussain, Syed; Ralph, Christy.

Eur Urol ; 69(3): 450-6, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26364551

17.

Infections and cancer in Uganda.

Robinson, Angus; Katongale-Mbidde, Edward.

Lancet ; 361(9357): 614, 2003 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-12598172

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