Detalhe da pesquisa
1.
Accurate and reliable prediction of relative ligand binding potency in prospective drug discovery by way of a modern free-energy calculation protocol and force field.
J Am Chem Soc
; 137(7): 2695-703, 2015 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-25625324
2.
Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors.
Bioorg Med Chem Lett
; 21(7): 2098-101, 2011 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21353545
3.
Synthesis and structure based optimization of novel Akt inhibitors.
Bioorg Med Chem Lett
; 18(11): 3359-63, 2008 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18456494
4.
Prospective Evaluation of Free Energy Calculations for the Prioritization of Cathepsin L Inhibitors.
J Med Chem
; 60(6): 2485-2497, 2017 03 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-28287264
5.
Recent advances in the discovery of small molecule inhibitors of interleukin-1 receptor-associated kinase 4 (IRAK4) as a therapeutic target for inflammation and oncology disorders.
J Med Chem
; 58(1): 96-110, 2015 Jan 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-25479567
6.
Selective interleukin-1 receptor-associated kinase 4 inhibitors for the treatment of autoimmune disorders and lymphoid malignancy.
J Exp Med
; 212(13): 2189-201, 2015 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26621451
7.
Design of selective, ATP-competitive inhibitors of Akt.
J Med Chem
; 53(12): 4615-22, 2010 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-20481595