Detalhe da pesquisa
1.
Post-translational modifications clustering within proteolytic domains decrease mutant huntingtin toxicity.
J Biol Chem
; 292(47): 19238-19249, 2017 11 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972180
2.
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.
J Proteome Res
; 16(8): 2692-2708, 2017 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28653853
3.
Transgenic mouse model expressing the caspase 6 fragment of mutant huntingtin.
J Neurosci
; 32(1): 183-93, 2012 Jan 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22219281
4.
Cysteamine Protects Neurons from Mutant Huntingtin Toxicity.
J Huntingtons Dis
; 8(2): 129-143, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30856117
5.
Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1.
Nat Commun
; 7: 11792, 2016 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27273569
6.
Sox11 Reduces Caspase-6 Cleavage and Activity.
PLoS One
; 10(10): e0141439, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26505998
7.
Phosphorylation of mutant huntingtin at serine 116 modulates neuronal toxicity.
PLoS One
; 9(2): e88284, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24505464