Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Sulfatase 2 (SULF2) Monoclonal Antibody 5D5 Suppresses Human Cholangiocarcinoma Xenograft Growth Through Regulation of a SULF2-Platelet-Derived Growth Factor Receptor Beta-Yes-Associated Protein Signaling Axis.

Luo, Xin; Campbell, Nellie A; He, Li; O'Brien, Daniel R; Singer, Mark S; Lemjabbar-Alaoui, Hassan; Ahn, Keun Soo; Smoot, Rory; Torbenson, Michael S; Rosen, Steven D; Roberts, Lewis R.

Hepatology ; 74(3): 1411-1428, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-33735525

2.

High endothelial venules through a transcriptomics lens.

Rosen, Steven D; Daneman, Richard.

Nat Immunol ; 15(10): 906-8, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25232814

3.

Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs.

Kanda, Hidenobu; Newton, Rebecca; Klein, Russell; Morita, Yuka; Gunn, Michael D; Rosen, Steven D.

Nat Immunol ; 9(4): 415-23, 2008 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-18327261

4.

Galactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissue.

Patnode, Michael L; Cheng, Chu-Wen; Chou, Chi-Chi; Singer, Mark S; Elin, Matilda S; Uchimura, Kenji; Crocker, Paul R; Khoo, Kay-Hooi; Rosen, Steven D.

J Biol Chem ; 288(37): 26533-45, 2013 Sep 13.

Artigo em Inglês | MEDLINE | ID: mdl-23880769

5.

Autotaxin through lysophosphatidic acid stimulates polarization, motility, and transendothelial migration of naive T cells.

Zhang, Yafeng; Chen, Yi-Chun Maria; Krummel, Matthew F; Rosen, Steven D.

J Immunol ; 189(8): 3914-24, 2012 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-22962684

6.

KSGal6ST generates galactose-6-O-sulfate in high endothelial venules but does not contribute to L-selectin-dependent lymphocyte homing.

Patnode, Michael L; Yu, Shin-Yi; Cheng, Chu-Wen; Ho, Ming-Yi; Tegesjö, Lotten; Sakuma, Keiichiro; Uchimura, Kenji; Khoo, Kay-Hooi; Kannagi, Reiji; Rosen, Steven D.

Glycobiology ; 23(3): 381-94, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23254996

7.

Functional contributions of N- and O-glycans to L-selectin ligands in murine and human lymphoid organs.

Arata-Kawai, Hanayo; Singer, Mark S; Bistrup, Annette; Zante, Annemieke van; Wang, Yang-Qing; Ito, Yuki; Bao, Xingfeng; Hemmerich, Stefan; Fukuda, Minoru; Rosen, Steven D.

Am J Pathol ; 178(1): 423-33, 2011 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-21224079

8.

"Home sweet home" for lymphocytes.

Rosen, Steven D; Arata-Kawai, Hanayo.

Blood ; 114(3): 499-500, 2009 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-19608758

9.

Direct detection of HSulf-1 and HSulf-2 activities on extracellular heparan sulfate and their inhibition by PI-88.

Hossain, Md Motarab; Hosono-Fukao, Tomomi; Tang, Renhong; Sugaya, Noriko; van Kuppevelt, Toin H; Jenniskens, Guido J; Kimata, Koji; Rosen, Steven D; Uchimura, Kenji.

Glycobiology ; 20(2): 175-86, 2010 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-19822709

10.

Lymphocyte-HEV interactions in lymph nodes of a sulfotransferase-deficient mouse.

van Zante, Annemieke; Gauguet, Jean-Marc; Bistrup, Annette; Tsay, Durwin; von Andrian, Ulrich H; Rosen, Steven D.

J Exp Med ; 198(9): 1289-300, 2003 Nov 03.

Artigo em Inglês | MEDLINE | ID: mdl-14597732

11.

Gene trap disruption of the mouse heparan sulfate 6-O-endosulfatase gene, Sulf2.

Lum, David H; Tan, Jenille; Rosen, Steven D; Werb, Zena.

Mol Cell Biol ; 27(2): 678-88, 2007 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-17116694

12.

Endoglycan, a member of the CD34 family of sialomucins, is a ligand for the vascular selectins.

Kerr, Sheena C; Fieger, Claudia B; Snapp, Karen R; Rosen, Steven D.

J Immunol ; 181(2): 1480-90, 2008 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-18606703

13.

Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis.

Yang, Jiwei; Rosen, Steven D; Bendele, Philip; Hemmerich, Stefan.

BMC Immunol ; 7: 12, 2006 Jun 13.

Artigo em Inglês | MEDLINE | ID: mdl-16772045

14.

Measuring the activities of the Sulfs: two novel heparin/heparan sulfate endosulfatases.

Uchimura, Kenji; Morimoto-Tomita, Megumi; Rosen, Steven D.

Methods Enzymol ; 416: 243-53, 2006.

Artigo em Inglês | MEDLINE | ID: mdl-17113870

15.

HSulf-2, an extracellular endoglucosamine-6-sulfatase, selectively mobilizes heparin-bound growth factors and chemokines: effects on VEGF, FGF-1, and SDF-1.

Uchimura, Kenji; Morimoto-Tomita, Megumi; Bistrup, Annette; Li, Jessica; Lyon, Malcolm; Gallagher, John; Werb, Zena; Rosen, Steven D.

BMC Biochem ; 7: 2, 2006 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-16417632

16.

Expression of the extracellular sulfatase SULF2 is associated with squamous cell carcinoma of the head and neck.

Flowers, Sarah A; Zhou, Xin; Wu, Jing; Wang, Yiwen; Makambi, Kepher; Kallakury, Bhaskar V; Singer, Mark S; Rosen, Steven D; Davidson, Bruce; Goldman, Radoslav.

Oncotarget ; 7(28): 43177-43187, 2016 Jul 12.

Artigo em Inglês | MEDLINE | ID: mdl-27223083

17.

Sulf-2, a proangiogenic heparan sulfate endosulfatase, is upregulated in breast cancer.

Morimoto-Tomita, Megumi; Uchimura, Kenji; Bistrup, Annette; Lum, David H; Egeblad, Mikala; Boudreau, Nancy; Werb, Zena; Rosen, Steven D.

Neoplasia ; 7(11): 1001-10, 2005 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-16331886

18.

A HEV-restricted sulfotransferase is expressed in rheumatoid arthritis synovium and is induced by lymphotoxin-alpha/beta and TNF-alpha in cultured endothelial cells.

Pablos, José L; Santiago, Begoña; Tsay, Durwin; Singer, Mark S; Palao, Guillermo; Galindo, María; Rosen, Steven D.

BMC Immunol ; 6: 6, 2005 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-15752429

19.

Differential gene expression profile of human tonsil high endothelial cells: implications for lymphocyte trafficking.

Palmeri, Diana; Zuo, Feng-Rong; Rosen, Steven D; Hemmerich, Stefan.

J Leukoc Biol ; 75(5): 910-27, 2004 May.

Artigo em Inglês | MEDLINE | ID: mdl-14761935

20.

SULF2, a heparan sulfate endosulfatase, is present in the blood of healthy individuals and increases in cirrhosis.

Singer, Mark S; Phillips, Joanna J; Lemjabbar-Alaoui, Hassan; Wang, Yang Qing; Wu, Jing; Goldman, Radoslav; Rosen, Steven D.

Clin Chim Acta ; 440: 72-8, 2015 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-25444749

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