Detalhe da pesquisa
1.
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Mol Syst Biol
; 20(6): 719-740, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38580884
2.
Pseudo-mutant P53 is a unique phenotype of DNMT3A-mutated pre-leukemia.
Haematologica
; 107(11): 2548-2561, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35199506
3.
Mutant p53 oncogenicity: dominant-negative or gain-of-function?
Carcinogenesis
; 41(12): 1635-1647, 2020 12 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-33159515
4.
The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice.
PLoS Pathog
; 14(5): e1007044, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29727445
5.
Diverse p53/DNA binding modes expand the repertoire of p53 response elements.
Proc Natl Acad Sci U S A
; 114(40): 10624-10629, 2017 10 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-28912355
6.
The HIV gp41 Fusion Protein Inhibits T-Cell Activation through the Lentiviral Lytic Peptide 2 Motif.
Biochemistry
; 58(6): 818-832, 2019 02 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30602116
7.
Dysfunctional diversity of p53 proteins in adult acute myeloid leukemia: projections on diagnostic workup and therapy.
Blood
; 130(6): 699-712, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607134
8.
Cellular heterogeneity mediates inherent sensitivity-specificity tradeoff in cancer targeting by synthetic circuits.
Proc Natl Acad Sci U S A
; 113(29): 8133-8, 2016 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-27385823
9.
Gain-of-Function Mutant p53: All the Roads Lead to Tumorigenesis.
Int J Mol Sci
; 20(24)2019 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31817996
10.
p53 and its mutants on the slippery road from stemness to carcinogenesis.
Carcinogenesis
; 38(4): 347-358, 2017 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-28334334
11.
Immune deficiency augments the prevalence of p53 loss of heterozygosity in spontaneous tumors but not bi-directional loss of heterozygosity in bone marrow progenitors.
Int J Cancer
; 140(6): 1364-1369, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28008605
12.
Rescue of embryonic stem cells from cellular transformation by proteomic stabilization of mutant p53 and conversion into WT conformation.
Proc Natl Acad Sci U S A
; 111(19): 7006-11, 2014 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-24778235
13.
Pla2g16 phospholipase mediates gain-of-function activities of mutant p53.
Proc Natl Acad Sci U S A
; 111(30): 11145-50, 2014 Jul 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25024203
14.
p53 orchestrates between normal differentiation and cancer.
Semin Cancer Biol
; 32: 10-7, 2015 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24406212
15.
Corrigendum to: The role of p53 in base excision repair following genotoxic stress.
Carcinogenesis
; 42(6): 903, 2021 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33991083
16.
Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect.
Cancer Cell
; 11(2): 133-46, 2007 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-17292825
17.
On a fundamental structure of gene networks in living cells.
Proc Natl Acad Sci U S A
; 109(12): 4702-7, 2012 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-22392990
18.
The paradigm of mutant p53-expressing cancer stem cells and drug resistance.
Carcinogenesis
; 35(6): 1196-208, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24658181
19.
Various p53 mutant proteins differently regulate the Ras circuit to induce a cancer-related gene signature.
J Cell Sci
; 125(Pt 13): 3144-52, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22427690
20.
Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.
J Cell Sci
; 125(Pt 22): 5578-86, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22899716