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2.
Clin Dermatol ; 40(6): 716-727, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35907577

RESUMO

Melanotic lupus erythematosus (LE) is a rare and newly described form of chronic cutaneous LE. In this review, we have synthesized existing data on the epidemiologic, clinical, histologic, and immunologic features of melanotic LE. We performed a systematic review using PubMed to identify eligible publications. Eight contributions fulfilled the eligibility criteria and were included in the qualitative synthesis. Twenty-eight patients with a mean age of 57.7 years were included. All patients had medium to dark skin phototypes. The lesions presented either as solitary and localized, poorly limited, round, or oval patches (50%) or as a more diffuse or generalized, sometimes reticulated, hyperpigmentation (50%). Patients diagnosed with systemic LE accounted for 14% of included cases. Antinuclear antibodies were positive in 10.7% of cases. Hydroxychloroquine and topical steroids were the most commonly used treatments. Complete resolution of the lesions was noted in 27.27% of cases. No patient experienced atrophy, destruction, or deformity of the skin. Melanotic LE appears to affect mainly patients with dark phototypes. It is characterized by late age at the onset of disease and an overall good prognosis.


Assuntos
Lúpus Eritematoso Cutâneo , Lúpus Eritematoso Discoide , Lúpus Eritematoso Sistêmico , Humanos , Pessoa de Meia-Idade , Lúpus Eritematoso Cutâneo/diagnóstico , Lúpus Eritematoso Cutâneo/tratamento farmacológico , Lúpus Eritematoso Discoide/diagnóstico , Lúpus Eritematoso Discoide/tratamento farmacológico , Lúpus Eritematoso Discoide/epidemiologia , Lúpus Eritematoso Sistêmico/diagnóstico , Pele/patologia , Anticorpos Antinucleares
3.
Clin Case Rep ; 9(7): e04542, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34336212

RESUMO

SARS-CoV-2, the virus that causes coronavirus disease 2019 (COVID-19), is associated with flares of psoriasis in patients with well-documented disease. Both viral infection and medications used for treatment, like hydroxychloroquine, were incriminated. Herein, we report the case of a 25-year-old male patient who presented a first-onset guttate psoriasis following a COVID-19 infection. We have not found previous descriptions of de novo guttate psoriasis post-COVID-19.

4.
Clin Case Rep ; 9(8): e04665, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34430023

RESUMO

Miliaria crystallina is frequently seen in intensive care patients. This skin condition should be known by both anesthesiologists and dermatologists to avoid unnecessary investigations.

5.
Int J Dermatol ; 60(11): 1368-1372, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34081330

RESUMO

BACKGROUND: Lichen planus (LP) is a chronic inflammatory dermatosis that affects the skin and the mucous membranes. The literature on the dermoscopic aspects of mucosal LP is still scarce. This study aimed to describe the dermoscopic aspects of mucosal LP and to provide a comprehensive updated summary of the literature. METHODS: This was a cross-sectional, multicenter study conducted in Charles Nicolle, La Rabta, and Habib Thameur hospitals from December 2019 to October 2020. We included patients with histologically confirmed mucosal LP for whom a dermoscopic examination was performed. RESULTS: Twenty-seven patients were enrolled. The main dermoscopic structures observed were as follows: Wickham's striae (WS) (91%), vessels (88%), pigmentated structures (41%), erosions (63%), scales (34%), and blunting of lingual papillae (3.1%). WS patterns were as follows: reticular (67%), radial (48%), annular (30%), globular (15%), dotted/starry sky (15%), and veil-like blue or grey-white homogenous pattern (19%). Vascular structures were as follows: linear (85%), dotted (70%), looped (22%), and peripheral sea anemone-like vessels (37%). These vessels were distributed in a radial arrangement at the periphery of the lesions in 67% of the cases. Pigmented structures included brown/blue globules (33%), grey-blue dots (30%), and brown dots (26%). CONCLUSION: Dermoscopic features of mucosal LP are varied. WS is the hallmark of LP. The distribution and aspects of WS in mucosal LP were slightly different from those described in cutaneous LP. Physicians should be aware of these dermoscopic features that could help differentiate LP from other mucosal inflammatory diseases.


Assuntos
Dermatite , Líquen Plano , Estudos Transversais , Dermoscopia , Humanos , Líquen Plano/diagnóstico por imagem , Mucosa
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