Detalhe da pesquisa
1.
Bivalent molecular mimicry by ADP protects metal redox state and promotes coenzyme B12 repair.
Proc Natl Acad Sci U S A
; 120(11): e2220677120, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36888659
2.
Cobalt-Sulfur Coordination Chemistry Drives B12 Loading onto Methionine Synthase.
J Am Chem Soc
; 2023 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-37916782
3.
Coordination Chemistry Controls Coenzyme B12 Synthesis by Human Adenosine Triphosphate:Cob(I)alamin Adenosyltransferase.
Inorg Chem
; 62(32): 12630-12633, 2023 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37526260
4.
Mobile loop dynamics in adenosyltransferase control binding and reactivity of coenzyme B12.
Proc Natl Acad Sci U S A
; 117(48): 30412-30422, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33199623
5.
Patient mutations in human ATP:cob(I)alamin adenosyltransferase differentially affect its catalytic versus chaperone functions.
J Biol Chem
; 297(6): 101373, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34757128
6.
The human B12 trafficking protein CblC processes nitrocobalamin.
J Biol Chem
; 295(28): 9630-9640, 2020 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32457044
7.
Chlorocob(II)alamin Formation Which Enhances the Thiol Oxidase Activity of the B12-Trafficking Protein CblC.
Inorg Chem
; 59(21): 16065-16072, 2020 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33074687
8.
A distal ligand mutes the interaction of hydrogen sulfide with human neuroglobin.
J Biol Chem
; 292(16): 6512-6528, 2017 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28246171
9.
Coordination chemistry controls the thiol oxidase activity of the B12-trafficking protein CblC.
J Biol Chem
; 292(23): 9733-9744, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28442570
10.
Sacrificial Cobalt-Carbon Bond Homolysis in Coenzyme B12 as a Cofactor Conservation Strategy.
J Am Chem Soc
; 140(41): 13205-13208, 2018 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-30282455
11.
Methylfolate Trap Promotes Bacterial Thymineless Death by Sulfa Drugs.
PLoS Pathog
; 12(10): e1005949, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27760199
12.
Alpha- and Beta-Diastereoisomers of Phenylcobalamin from Cobalt-Arylation with Diphenyliodonium Chloride.
Chemistry
; 23(41): 9726-9731, 2017 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28557054
13.
Antivitamin B12 Inhibition of the Human B12 -Processing Enzyme CblC: Crystal Structure of an Inactive Ternary Complex with Glutathione as the Cosubstrate.
Angew Chem Int Ed Engl
; 56(26): 7387-7392, 2017 06 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-28544088
14.
Reply to Sysel et al.: Comment on the importance of using nitric oxide gas in the synthesis of nitrosylcobalamin and ICH-validated methods to assess purity and stability.
J Biol Chem
; 295(43): 14790, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097648
15.
Pathogenic mutations differentially affect the catalytic activities of the human B12-processing chaperone CblC and increase futile redox cycling.
J Biol Chem
; 290(18): 11393-402, 2015 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25809485
16.
Toward the Design of Photoresponsive Conditional Antivitamins B12: A Transient Absorption Study of an Arylcobalamin and an Alkynylcobalamin.
J Am Chem Soc
; 138(43): 14250-14256, 2016 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27797190
17.
Exogenous 5,6-dimethylbenzimidazole caused production of a non-functional tetrachloroethene reductive dehalogenase in Sulfurospirillum multivorans.
Environ Microbiol
; 16(11): 3361-9, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24433392
18.
Phenylethynylcobalamin: a light-stable and thermolysis-resistant organometallic vitamin B(12) derivative prepared by radical synthesis.
Angew Chem Int Ed Engl
; 52(43): 11406-9, 2013 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24030966
19.
Access to organometallic arylcobaltcorrins through radical synthesis: 4-ethylphenylcobalamin, a potential "antivitamin B(12)".
Angew Chem Int Ed Engl
; 52(9): 2606-10, 2013 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-23404623
20.
Architecture of the human G-protein-methylmalonyl-CoA mutase nanoassembly for B 12 delivery and repair.
bioRxiv
; 2023 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-36993209