1.
Pulm Circ
; 8(1): 2045893217746054, 2018.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29206084
RESUMO
Pulmonary arterial hypertension (PAH) shares many hallmarks with cancer. Cancer cells acquire their hallmarks by a pathological Darwinian evolution process built on the so-called cancer cell "identity crisis." Here we demonstrate that PAH shares the most striking features of the cancer identity crisis: the ectopic expression of normally silent tissue-specific genes.