Detalhe da pesquisa
1.
Evaluation of Platensimycin and Platensimycin-Inspired Thioether Analogues against Methicillin-Resistant Staphylococcus aureus in Topical and Systemic Infection Mouse Models.
Mol Pharm
; 16(7): 3065-3071, 2019 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31244223
2.
Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors.
Bioorg Med Chem Lett
; 24(1): 161-4, 2014 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24332487
3.
Small molecule amides as potent ROR-γ selective modulators.
Bioorg Med Chem Lett
; 23(2): 532-6, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23232056
4.
Imidazopyridines as selective CYP3A4 inhibitors.
Bioorg Med Chem Lett
; 22(4): 1611-4, 2012 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22264486
5.
Synthesis and SAR of tetrahydroisoquinolines as Rev-erbα agonists.
Bioorg Med Chem Lett
; 22(11): 3739-42, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22560469
6.
Morphing Natural Product Platensimycin via Heck, Sonogashira, and One-Pot Sonogashira/Cycloaddition Reactions to Produce Antibiotics with In Vivo Activity.
Antibiotics (Basel)
; 11(4)2022 Mar 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35453177
7.
Synthesis and SAR of 2-phenoxypyridines as novel c-Jun N-terminal kinase inhibitors.
Bioorg Med Chem Lett
; 21(23): 7072-5, 2011 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22004719
8.
Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors.
Bioorg Med Chem Lett
; 21(9): 2732-5, 2011 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21185177
9.
Characterization of dasatinib and its structural analogs as CYP3A4 mechanism-based inactivators and the proposed bioactivation pathways.
Drug Metab Dispos
; 37(6): 1242-50, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19282395
10.
Small Molecule c-jun-N-terminal Kinase (JNK) Inhibitors Protect Dopaminergic Neurons in a Model of Parkinson's Disease.
ACS Chem Neurosci
; 2(4): 198-206, 2011 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21666839
11.
Synthesis, biological evaluation, X-ray structure, and pharmacokinetics of aminopyrimidine c-jun-N-terminal kinase (JNK) inhibitors.
J Med Chem
; 53(1): 419-31, 2010 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-19947601