Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Cap-Snatching Leads to Novel Viral Proteins.

Russell, Alistair B.

Cell ; 181(7): 1450-1451, 2020 06 25.

Artigo em Inglês | MEDLINE | ID: mdl-32589954

2.

The use of single-cell RNA-seq to study heterogeneity at varying levels of virus-host interactions.

Swaminath, Sharmada; Russell, Alistair B.

PLoS Pathog ; 20(1): e1011898, 2024 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-38236826

3.

Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.

Ranum, Jordan N; Ledwith, Mitchell P; Alnaji, Fadi G; Diefenbacher, Meghan; Orton, Richard; Sloan, Elizabeth; Güereca, Melissa; Feltman, Elizabeth M; Smollett, Katherine; da Silva Filipe, Ana; Conley, Michaela; Russell, Alistair B; Brooke, Christopher B; Hutchinson, Edward; Mehle, Andrew.

Nucleic Acids Res ; 52(6): 3199-3212, 2024 Apr 12.

Artigo em Inglês | MEDLINE | ID: mdl-38407436

4.

Maximal interferon induction by influenza lacking NS1 is infrequent owing to requirements for replication and export.

Vicary, Alison C; Mendes, Marisa; Swaminath, Sharmada; Lekbua, Asama; Reddan, Jack; Rodriguez, Zaida K; Russell, Alistair B.

PLoS Pathog ; 19(4): e1010943, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-37068114

5.

Similarities in the induction of the intracellular pathogen response in Caenorhabditis elegans and the type I interferon response in mammals.

Lazetic, Vladimir; Batachari, Lakshmi E; Russell, Alistair B; Troemel, Emily R.

Bioessays ; 45(11): e2300097, 2023 11.

Artigo em Inglês | MEDLINE | ID: mdl-37667453

6.

In Vivo Profiling of Individual Multiciliated Cells during Acute Influenza A Virus Infection.

Hamele, Cait E; Russell, Alistair B; Heaton, Nicholas S.

J Virol ; 96(14): e0050522, 2022 07 27.

Artigo em Inglês | MEDLINE | ID: mdl-35867557

7.

Library-based analysis reveals segment and length dependent characteristics of defective influenza genomes.

Mendes, Marisa; Russell, Alistair B.

PLoS Pathog ; 17(12): e1010125, 2021 12.

Artigo em Inglês | MEDLINE | ID: mdl-34882752

8.

Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity.

Russell, Alistair B; Elshina, Elizaveta; Kowalsky, Jacob R; Te Velthuis, Aartjan J W; Bloom, Jesse D.

J Virol ; 93(14)2019 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-31068418

9.

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.

Russell, Alistair B; LeRoux, Michele; Hathazi, Krisztina; Agnello, Danielle M; Ishikawa, Takahiko; Wiggins, Paul A; Wai, Sun Nyunt; Mougous, Joseph D.

Nature ; 496(7446): 508-12, 2013 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-23552891

10.

Human symbionts inject and neutralize antibacterial toxins to persist in the gut.

Wexler, Aaron G; Bao, Yiqiao; Whitney, John C; Bobay, Louis-Marie; Xavier, Joao B; Schofield, Whitman B; Barry, Natasha A; Russell, Alistair B; Tran, Bao Q; Goo, Young Ah; Goodlett, David R; Ochman, Howard; Mougous, Joseph D; Goodman, Andrew L.

Proc Natl Acad Sci U S A ; 113(13): 3639-44, 2016 Mar 29.

Artigo em Inglês | MEDLINE | ID: mdl-26957597

11.

Type VI secretion delivers bacteriolytic effectors to target cells.

Russell, Alistair B; Hood, Rachel D; Bui, Nhat Khai; LeRoux, Michele; Vollmer, Waldemar; Mougous, Joseph D.

Nature ; 475(7356): 343-7, 2011 Jul 20.

Artigo em Inglês | MEDLINE | ID: mdl-21776080

12.

Genetically distinct pathways guide effector export through the type VI secretion system.

Whitney, John C; Beck, Christina M; Goo, Young Ah; Russell, Alistair B; Harding, Brittany N; De Leon, Justin A; Cunningham, David A; Tran, Bao Q; Low, David A; Goodlett, David R; Hayes, Christopher S; Mougous, Joseph D.

Mol Microbiol ; 92(3): 529-42, 2014 May.

Artigo em Inglês | MEDLINE | ID: mdl-24589350

13.

Quantitative single-cell characterization of bacterial interactions reveals type VI secretion is a double-edged sword.

LeRoux, Michele; De Leon, Justin A; Kuwada, Nathan J; Russell, Alistair B; Pinto-Santini, Delia; Hood, Rachel D; Agnello, Danielle M; Robertson, Stephen M; Wiggins, Paul A; Mougous, Joseph D.

Proc Natl Acad Sci U S A ; 109(48): 19804-9, 2012 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-23150540

14.

Identification, structure, and function of a novel type VI secretion peptidoglycan glycoside hydrolase effector-immunity pair.

Whitney, John C; Chou, Seemay; Russell, Alistair B; Biboy, Jacob; Gardiner, Taylor E; Ferrin, Michael A; Brittnacher, Mitchell; Vollmer, Waldemar; Mougous, Joseph D.

J Biol Chem ; 288(37): 26616-24, 2013 Sep 13.

Artigo em Inglês | MEDLINE | ID: mdl-23878199

15.

Genetic disassembly and combinatorial reassembly identify a minimal functional repertoire of type III effectors in Pseudomonas syringae.

Cunnac, Sébastien; Chakravarthy, Suma; Kvitko, Brian H; Russell, Alistair B; Martin, Gregory B; Collmer, Alan.

Proc Natl Acad Sci U S A ; 108(7): 2975-80, 2011 Feb 15.

Artigo em Inglês | MEDLINE | ID: mdl-21282655

16.

Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.

Ranum, Jordan N; Ledwith, Mitchell P; Alnaji, Fadi G; Diefenbacher, Meghan; Orton, Richard; Sloan, Elisabeth; Guereca, Melissa; Feltman, Elizabeth M; Smollett, Katherine; da Silva Filipe, Ana; Conley, Michaela; Russell, Alistair B; Brooke, Christopher B; Hutchinson, Edward; Mehle, Andrew.

bioRxiv ; 2024 Feb 07.

Artigo em Inglês | MEDLINE | ID: mdl-38168266

17.

Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine.

Worley, Jay N; Russell, Alistair B; Wexler, Aaron G; Bronstein, Philip A; Kvitko, Brian H; Krasnoff, Stuart B; Munkvold, Kathy R; Swingle, Bryan; Gibson, Donna M; Collmer, Alan.

J Bacteriol ; 195(2): 287-96, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-23144243

18.

Respiratory viruses: New frontiers-a Keystone Symposia report.

Cable, Jennifer; Sun, Jie; Cheon, In Su; Vaughan, Andrew E; Castro, Italo A; Stein, Sydney R; López, Carolina B; Gostic, Katelyn M; Openshaw, Peter J M; Ellebedy, Ali H; Wack, Andreas; Hutchinson, Edward; Thomas, Mallory M; Langlois, Ryan A; Lingwood, Daniel; Baker, Steven F; Folkins, Melanie; Foxman, Ellen F; Ward, Andrew B; Schwemmle, Martin; Russell, Alistair B; Chiu, Christopher; Ganti, Ketaki; Subbarao, Kanta; Sheahan, Timothy P; Penaloza-MacMaster, Pablo; Eddens, Taylor.

Ann N Y Acad Sci ; 1522(1): 60-73, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36722473

19.

Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context.

Radkov, Atanas; Sapiro, Anne L; Flores, Sebastian; Henderson, Corey; Saunders, Hayden; Kim, Rachel; Massa, Steven; Thompson, Samuel; Mateusiak, Chase; Biboy, Jacob; Zhao, Ziyi; Starita, Lea M; Hatleberg, William L; Vollmer, Waldemar; Russell, Alistair B; Simorre, Jean-Pierre; Anthony-Cahill, Spencer; Brzovic, Peter; Hayes, Beth; Chou, Seemay.

Elife ; 112022 06 28.

Artigo em Inglês | MEDLINE | ID: mdl-35762582

20.

Deletions in the repertoire of Pseudomonas syringae pv. tomato DC3000 type III secretion effector genes reveal functional overlap among effectors.

Kvitko, Brian H; Park, Duck Hwan; Velásquez, André C; Wei, Chia-Fong; Russell, Alistair B; Martin, Gregory B; Schneider, David J; Collmer, Alan.

PLoS Pathog ; 5(4): e1000388, 2009 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-19381254

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Cap-Snatching Leads to Novel Viral Proteins.

The use of single-cell RNA-seq to study heterogeneity at varying levels of virus-host interactions.

Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.

Maximal interferon induction by influenza lacking NS1 is infrequent owing to requirements for replication and export.

Similarities in the induction of the intracellular pathogen response in Caenorhabditis elegans and the type I interferon response in mammals.

In Vivo Profiling of Individual Multiciliated Cells during Acute Influenza A Virus Infection.

Library-based analysis reveals segment and length dependent characteristics of defective influenza genomes.

Single-Cell Virus Sequencing of Influenza Infections That Trigger Innate Immunity.

Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors.

Human symbionts inject and neutralize antibacterial toxins to persist in the gut.

Type VI secretion delivers bacteriolytic effectors to target cells.

Genetically distinct pathways guide effector export through the type VI secretion system.

Quantitative single-cell characterization of bacterial interactions reveals type VI secretion is a double-edged sword.

Identification, structure, and function of a novel type VI secretion peptidoglycan glycoside hydrolase effector-immunity pair.

Genetic disassembly and combinatorial reassembly identify a minimal functional repertoire of type III effectors in Pseudomonas syringae.

Cryptic proteins translated from deletion-containing viral genomes dramatically expand the influenza virus proteome.

Pseudomonas syringae pv. tomato DC3000 CmaL (PSPTO4723), a DUF1330 family member, is needed to produce L-allo-isoleucine, a precursor for the phytotoxin coronatine.

Respiratory viruses: New frontiers-a Keystone Symposia report.

Antibacterial potency of type VI amidase effector toxins is dependent on substrate topology and cellular context.

Deletions in the repertoire of Pseudomonas syringae pv. tomato DC3000 type III secretion effector genes reveal functional overlap among effectors.