Detalhe da pesquisa
1.
4-Octyl itaconate reduces influenza A replication by targeting the nuclear export protein CRM1.
J Virol
; 97(10): e0132523, 2023 10 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37823646
2.
A first-in-human study of the novel immunology antibody-drug conjugate, ABBV-3373, in healthy participants.
Br J Clin Pharmacol
; 90(1): 189-199, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37596703
3.
Dual Blockade of Interleukin-1ß and Interleukin-17A Reduces Murine Arthritis Pathogenesis but Also Leads to Spontaneous Skin Infections in Nonhuman Primates.
J Pharmacol Exp Ther
; 364(3): 474-484, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311111
4.
Modeling the clinical phenotype of BTK inhibition in the mature murine immune system.
J Immunol
; 193(1): 185-97, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24899507
5.
Transient low-dose methotrexate induces tolerance to murine anti-thymocyte globulin and together they promote long-term allograft survival.
J Immunol
; 189(2): 732-43, 2012 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22711884
6.
An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases.
Sci Transl Med
; 16(739): eadd8936, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38507467
7.
Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways.
Nat Commun
; 15(1): 4096, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38750019
8.
Synovial Inflammatory Pathways Characterize Anti-TNF-Responsive Rheumatoid Arthritis Patients.
Arthritis Rheumatol
; 74(12): 1916-1927, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35854416
9.
Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages.
Cell Metab
; 34(3): 487-501.e8, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235776
10.
Reducing glycosphingolipid biosynthesis in airway cells partially ameliorates disease manifestations in a mouse model of asthma.
Int Immunol
; 22(7): 593-603, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20497953
11.
Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression.
J Invest Dermatol
; 141(11): 2730-2740.e9, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965402
12.
Biomarkers for the clinical development of antiviral therapies.
Cytometry B Clin Cytom
; 100(1): 19-32, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34542933
13.
Homeostatic role of transforming growth factor-beta in the oral cavity and esophagus of mice and its expression by mast cells in these tissues.
Am J Pathol
; 174(6): 2137-49, 2009 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-19406991
14.
The Immunomodulatory Metabolite Itaconate Modifies NLRP3 and Inhibits Inflammasome Activation.
Cell Metab
; 32(3): 468-478.e7, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32791101
15.
Human endothelial precursor cells express tumor endothelial marker 1/endosialin/CD248.
Mol Cancer Ther
; 7(8): 2536-46, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18723498
16.
Ultrasound imaging accurately detects skin thickening in a mouse scleroderma model.
Ultrasound Med Biol
; 34(8): 1239-47, 2008 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-18359143
17.
Safety, Tolerability, and Pharmacodynamics of ABT-122, a Tumor Necrosis Factor- and Interleukin-17-Targeted Dual Variable Domain Immunoglobulin, in Patients With Rheumatoid Arthritis.
Arthritis Rheumatol
; 69(12): 2283-2291, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-28941216
18.
Murine antithymocyte globulin T-cell depletion is mediated predominantly by macrophages, but the Fas/FasL pathway selectively targets regulatory T cells.
Transplantation
; 92(5): 523-8, 2011 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21804441
19.
A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model.
Transplantation
; 90(3): 260-9, 2010 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20712076
20.
In vivo characterization of rabbit anti-mouse thymocyte globulin: a surrogate for rabbit anti-human thymocyte globulin.
Transplantation
; 88(2): 170-9, 2009 Jul 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-19623011