Detalhe da pesquisa
1.
Third target of rapamycin complex negatively regulates development of quiescence in Trypanosoma brucei.
Proc Natl Acad Sci U S A
; 109(36): 14399-404, 2012 Sep 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-22908264
2.
A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas' disease.
Trends Parasitol
; 40(3): 211-213, 2024 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-38368155
3.
Target of rapamycin (TOR) kinase in Trypanosoma brucei: an extended family.
Biochem Soc Trans
; 41(4): 934-8, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23863159
4.
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science
; 380(6652): 1349-1356, 2023 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384702
5.
The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria-mediated apoptosis and DNA damage in p53 mutant leukemic T cells.
Int J Cancer
; 130(5): 1195-207, 2012 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21455989
6.
CLK1/CLK2-driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics.
Commun Biol
; 5(1): 1305, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36437406
7.
A CLK1-KKT2 Signaling Pathway Regulating Kinetochore Assembly in Trypanosoma brucei.
mBio
; 12(3): e0068721, 2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34128702
8.
Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors.
Nat Microbiol
; 5(10): 1207-1216, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32661312
9.
The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei.
Cell Rep
; 17(3): 660-670, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27732844
10.
Establishment of a structure-activity relationship of 1H-imidazo[4,5-c]quinoline-based kinase inhibitor NVP-BEZ235 as a lead for African sleeping sickness.
J Med Chem
; 57(11): 4834-48, 2014 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24805946
11.
The susceptibility of trypanosomatid pathogens to PI3/mTOR kinase inhibitors affords a new opportunity for drug repurposing.
PLoS Negl Trop Dis
; 5(8): e1297, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21886855
12.
Concentración espermática mínima requerida para inseminación intrauterina mediante capacitación por migración ascendente / Low sperm concentration required to IUI through training by upward migration
Rev. obstet. ginecol. Venezuela
; 74(3): 177-183, sep. 2014. ilus, tab
Artigo
em Espanhol
| LILACS | ID: lil-740391