Detalhe da pesquisa
1.
Use of pure recombinant human enzymes to assess the disease-causing potential of missense mutations in urea cycle disorders, applied to N-acetylglutamate synthase deficiency.
J Inherit Metab Dis
; 2024 May 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740568
2.
Structural Plasticity of LL-37 Indicates Elaborate Functional Adaptation Mechanisms to Bacterial Target Structures.
Int J Mol Sci
; 22(10)2021 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34068993
3.
Metal Positions and Translocation Pathways of the Dodecameric Ferritin-like Protein Dps.
Inorg Chem
; 58(17): 11351-11363, 2019 Sep 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31433627
4.
The antibacterial prodrug activator Rv2466c is a mycothiol-dependent reductase in the oxidative stress response of Mycobacterium tuberculosis.
J Biol Chem
; 292(32): 13097-13110, 2017 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28620052
5.
Structural basis of phosphatidyl-myo-inositol mannosides biosynthesis in mycobacteria.
Biochim Biophys Acta Mol Cell Biol Lipids
; 1862(11): 1355-1367, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27826050
6.
Understanding N-Acetyl-L-Glutamate Synthase Deficiency: Mutational Spectrum, Impact of Clinical Mutations on Enzyme Functionality, and Structural Considerations.
Hum Mutat
; 37(7): 679-94, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27037498
7.
A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase.
Angew Chem Int Ed Engl
; 54(34): 9898-902, 2015 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26136334
8.
Functional dissection of N-acetylglutamate synthase (ArgA) of Pseudomonas aeruginosa and restoration of its ancestral N-acetylglutamate kinase activity.
J Bacteriol
; 194(11): 2791-801, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22447897
9.
The role of bacterial transport systems in the removal of host antimicrobial peptides in Gram-negative bacteria.
FEMS Microbiol Rev
; 46(6)2022 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35749576
10.
Auxiliary active site mutations enhance the glycosynthase activity of a GH18 chitinase for polymerization of chitooligosaccharides.
Carbohydr Polym
; 252: 117121, 2021 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33183587
11.
The structure of the antimicrobial human cathelicidin LL-37 shows oligomerization and channel formation in the presence of membrane mimics.
Sci Rep
; 10(1): 17356, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33060695
12.
Structure and function of the Ts2631 endolysin of Thermus scotoductus phage vB_Tsc2631 with unique N-terminal extension used for peptidoglycan binding.
Sci Rep
; 9(1): 1261, 2019 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30718611
13.
Site-directed mutagenesis studies of acetylglutamate synthase delineate the site for the arginine inhibitor.
FEBS Lett
; 582(7): 1081-6, 2008 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-18319063
14.
Expression and specificity of a chitin deacetylase from the nematophagous fungus Pochonia chlamydosporia potentially involved in pathogenicity.
Sci Rep
; 8(1): 2170, 2018 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29391415
15.
The Human Antimicrobial Peptides Dermcidin and LL-37 Show Novel Distinct Pathways in Membrane Interactions.
Front Chem
; 5: 86, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29164103
16.
Structural remodeling and oligomerization of human cathelicidin on membranes suggest fibril-like structures as active species.
Sci Rep
; 7(1): 15371, 2017 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-29133814
17.
Structural Snapshots and Loop Dynamics along the Catalytic Cycle of Glycosyltransferase GpgS.
Structure
; 25(7): 1034-1044.e3, 2017 07 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28625787
18.
Structural basis for selective recognition of acyl chains by the membrane-associated acyltransferase PatA.
Nat Commun
; 7: 10906, 2016 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-26965057
19.
Acidic pH and divalent cation sensing by PhoQ are dispensable for systemic salmonellae virulence.
Elife
; 4: e06792, 2015 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-26002083
20.
Antimicrobial peptides: has their time arrived?
Future Microbiol
; 10(7): 1103-6, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26118303