Detalhe da pesquisa
1.
A novel gain-of-function phosphorylation site modulates PTPN22 inhibition of TCR signaling.
J Biol Chem
; : 107393, 2024 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38777143
2.
Macromolecular crowding amplifies allosteric regulation of T-cell protein tyrosine phosphatase.
J Biol Chem
; 298(12): 102655, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36328244
3.
RPTPα phosphatase activity is allosterically regulated by the membrane-distal catalytic domain.
J Biol Chem
; 295(15): 4923-4936, 2020 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32139509
4.
Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy.
Sci Adv
; 10(5): eadg7887, 2024 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38295166
5.
Clustering of phosphatase RPTPα promotes Src signaling and the arthritogenic action of synovial fibroblasts.
Sci Signal
; 16(792): eabn8668, 2023 07 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402225
6.
Structural insights into inhibition of Bacillus anthracis sporulation by a novel class of non-heme globin sensor domains.
J Biol Chem
; 286(10): 8448-8458, 2011 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21216948
7.
Oxidative stress promotes fibrosis in systemic sclerosis through stabilization of a kinase-phosphatase complex.
JCI Insight
; 7(8)2022 04 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35451370
8.
Discovery of Orally Bioavailable Purine-Based Inhibitors of the Low-Molecular-Weight Protein Tyrosine Phosphatase.
J Med Chem
; 64(9): 5645-5653, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33914534
9.
Crystal structure of a complex between anthrax toxin and its host cell receptor.
Nature
; 430(7002): 905-8, 2004 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-15243628
10.
Carbon nanotube-based nanocarriers: the importance of keeping it clean.
J Nanosci Nanotechnol
; 10(8): 5293-301, 2010 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21125885
11.
PTPN22 phosphorylation acts as a molecular rheostat for the inhibition of TCR signaling.
Sci Signal
; 13(623)2020 03 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32184287
12.
Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Sci Adv
; 6(26): eaba4353, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637608
13.
Reduced expression of phosphatase PTPN2 promotes pathogenic conversion of Tregs in autoimmunity.
J Clin Invest
; 129(3): 1193-1210, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30620725
14.
Preliminary structural studies on the leucine-zipper homology region of the human protein Bap31.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 63(Pt 4): 297-9, 2007 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17401199
15.
PTP4A1 promotes TGFß signaling and fibrosis in systemic sclerosis.
Nat Commun
; 8(1): 1060, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-29057934
16.
Structure of anthrax lethal toxin prepore complex suggests a pathway for efficient cell entry.
J Gen Physiol
; 148(4): 313-24, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27670897
17.
Structure-based design of covalent Siah inhibitors.
Chem Biol
; 20(8): 973-82, 2013 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-23891150
18.
The crystal structure of a TIR domain from Arabidopsis thaliana reveals a conserved helical region unique to plants.
Protein Sci
; 19(1): 155-61, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19845004
19.
Crystal structure of a glycerophosphodiester phosphodiesterase (GDPD) from Thermotoga maritima (TM1621) at 1.60 A resolution.
Proteins
; 56(1): 167-70, 2004 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15162496
20.
Molecular mimicry in innate immunity: crystal structure of a bacterial TIR domain.
J Biol Chem
; 284(32): 21386-92, 2009 Aug 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-19535337