Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Management of adult patients with CMML undergoing allo-HCT: recommendations from the EBMT PH&G Committee.

Onida, Francesco; Gagelmann, Nico; Chalandon, Yves; Kobbe, Guido; Robin, Marie; Symeonidis, Argiris; de Witte, Theo M; Itzykson, Raphaël A; Jentzsch, Madlen; Platzbecker, Uwe; Santini, Valeria; Sanz, Guillermo F; Scheid, Christoph; Solary, Eric; Valent, Peter; Greco, Raffaela; Sánchez-Ortega, Isabel; Yakoub-Agha, Ibrahim; Pleyer, Lisa.

Blood ; 2024 Mar 17.

Artigo em Inglês | MEDLINE | ID: mdl-38493484

2.

Molecular and clinical presentation of UBA1-mutated myelodysplastic syndromes.

Sirenko, Maria; Bernard, Elsa; Creignou, Maria; Domenico, Dylan; Farina, Andrea; Arango Ossa, Juan Esteban; Kosmider, Olivier; Hasserjian, Robert P; Jädersten, Martin; Germing, Ulrich; Sanz, Guillermo F; van de Loosdrecht, Arjan A; Gurnari, Carmelo; Follo, Matilde Y; Thol, Felicitas R; Zamora, Lurdes; Pinheiro, Ronald Feitosa; Pellagatti, Andrea; Elias, Harold Kunal; Haase, Detlef Thomas; Sander, Birgitta; Orna, Elisa; Zoldan, Katharina; Eder, Lea Naomi; Sperr, Wolfgang R; Thalhammer, Renate; Ganster, Christina; Adès, Lionel; Tobiasson, Magnus; Palomo, Laura; Della Porta, Matteo Giovanni; Huberman, Kety H; Fenaux, Pierre; Belickova, Monika; Savona, Michael R; Klimek, Virginia; Santos, Fabio P S; Boultwood, Jacqueline; Kotsianidis, Ioannis; Santini, Valeria; Sole, Francesc; Platzbecker, Uwe; Heuser, Michael; Valent, Peter; Finelli, Carlo; Voso, Maria Teresa; Shih, Lee Yung; Ogawa, Seishi; Fontenay, Michaela; Jansen, Joop H.

Blood ; 2024 04 30.

Artigo em Inglês | MEDLINE | ID: mdl-38687605

3.

Imetelstat in patients with lower-risk myelodysplastic syndromes who have relapsed or are refractory to erythropoiesis-stimulating agents (IMerge): a multinational, randomised, double-blind, placebo-controlled, phase 3 trial.

Platzbecker, Uwe; Santini, Valeria; Fenaux, Pierre; Sekeres, Mikkael A; Savona, Michael R; Madanat, Yazan F; Díez-Campelo, Maria; Valcárcel, David; Illmer, Thomas; Jonásová, Anna; Belohlávková, Petra; Sherman, Laurie J; Berry, Tymara; Dougherty, Souria; Shah, Sheetal; Xia, Qi; Sun, Libo; Wan, Ying; Huang, Fei; Ikin, Annat; Navada, Shyamala; Feller, Faye; Komrokji, Rami S; Zeidan, Amer M.

Lancet ; 403(10423): 249-260, 2024 Jan 20.

Artigo em Inglês | MEDLINE | ID: mdl-38048786

4.

Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes.

Zeidan, Amer M; Platzbecker, Uwe; Bewersdorf, Jan Philipp; Stahl, Maximilian; Adès, Lionel; Borate, Uma; Bowen, David; Buckstein, Rena; Brunner, Andrew; Carraway, Hetty E; Daver, Naval; Díez-Campelo, Maria; de Witte, Theo; DeZern, Amy E; Efficace, Fabio; Garcia-Manero, Guillermo; Garcia, Jacqueline S; Germing, Ulrich; Giagounidis, Aristoteles; Griffiths, Elizabeth A; Hasserjian, Robert P; Hellström-Lindberg, Eva; Iastrebner, Marcelo; Komrokji, Rami; Kulasekararaj, Austin G; Malcovati, Luca; Miyazaki, Yasushi; Odenike, Olatoyosi; Santini, Valeria; Sanz, Guillermo; Scheinberg, Phillip; Stauder, Reinhard; van de Loosdrecht, Arjan A; Wei, Andrew H; Sekeres, Mikkael A; Fenaux, Pierre.

Blood ; 141(17): 2047-2061, 2023 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-36724453

5.

Efficacy and safety of luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): interim analysis of a phase 3, open-label, randomised controlled trial.

Platzbecker, Uwe; Della Porta, Matteo Giovanni; Santini, Valeria; Zeidan, Amer M; Komrokji, Rami S; Shortt, Jake; Valcarcel, David; Jonasova, Anna; Dimicoli-Salazar, Sophie; Tiong, Ing Soo; Lin, Chien-Chin; Li, Jiahui; Zhang, Jennie; Giuseppi, Ana Carolina; Kreitz, Sandra; Pozharskaya, Veronika; Keeperman, Karen L; Rose, Shelonitda; Shetty, Jeevan K; Hayati, Sheida; Vodala, Sadanand; Prebet, Thomas; Degulys, Andrius; Paolini, Stefania; Cluzeau, Thomas; Fenaux, Pierre; Garcia-Manero, Guillermo.

Lancet ; 402(10399): 373-385, 2023 07 29.

Artigo em Inglês | MEDLINE | ID: mdl-37311468

6.

TP53-altered acute myeloid leukemia and myelodysplastic syndrome with excess blasts should be approached as a single entity.

Shallis, Rory M; Daver, Naval G; Altman, Jessica K; Hasserjian, Robert P; Kantarjian, Hagop M; Platzbecker, Uwe; Santini, Valeria; Wei, Andrew H; Sallman, David A; Zeidan, Amer M.

Cancer ; 129(2): 175-180, 2023 01 15.

Artigo em Inglês | MEDLINE | ID: mdl-36397669

7.

A Nationwide Study of GATA2 Deficiency in Italy Reveals Novel Symptoms and Genotype-phenotype Association.

Roncareggi, Samuele; Girardi, Katia; Fioredda, Francesca; Pedace, Lucia; Arcuri, Luca; Badolato, Raffaele; Bonanomi, Sonia; Borlenghi, Erika; Cirillo, Emilia; Coliva, Tiziana; Consonni, Filippo; Conti, Francesca; Farruggia, Piero; Gambineri, Eleonora; Guerra, Fabiola; Locatelli, Franco; Mancuso, Gaia; Marzollo, Antonio; Masetti, Riccardo; Micalizzi, Concetta; Onofrillo, Daniela; Piccini, Matteo; Pignata, Claudio; Raddi, Marco Gabriele; Santini, Valeria; Vendemini, Francesca; Biondi, Andrea; Saettini, Francesco.

J Clin Immunol ; 43(8): 2192-2207, 2023 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-37837580

8.

Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes.

Fenaux, Pierre; Platzbecker, Uwe; Mufti, Ghulam J; Garcia-Manero, Guillermo; Buckstein, Rena; Santini, Valeria; Díez-Campelo, María; Finelli, Carlo; Cazzola, Mario; Ilhan, Osman; Sekeres, Mikkael A; Falantes, José F; Arrizabalaga, Beatriz; Salvi, Flavia; Giai, Valentina; Vyas, Paresh; Bowen, David; Selleslag, Dominik; DeZern, Amy E; Jurcic, Joseph G; Germing, Ulrich; Götze, Katharina S; Quesnel, Bruno; Beyne-Rauzy, Odile; Cluzeau, Thomas; Voso, Maria-Teresa; Mazure, Dominiek; Vellenga, Edo; Greenberg, Peter L; Hellström-Lindberg, Eva; Zeidan, Amer M; Adès, Lionel; Verma, Amit; Savona, Michael R; Laadem, Abderrahmane; Benzohra, Aziz; Zhang, Jennie; Rampersad, Anita; Dunshee, Diana R; Linde, Peter G; Sherman, Matthew L; Komrokji, Rami S; List, Alan F.

N Engl J Med ; 382(2): 140-151, 2020 01 09.

Artigo em Inglês | MEDLINE | ID: mdl-31914241

9.

Improved benefit of continuing luspatercept therapy: sub-analysis of patients with lower-risk MDS in the MEDALIST study.

Germing, Ulrich; Fenaux, Pierre; Platzbecker, Uwe; Buckstein, Rena; Santini, Valeria; Díez-Campelo, María; Yucel, Aylin; Tang, Derek; Fabre, Shannon; Zhang, George; Zoffoli, Roberto; Ha, Xianwei; Miteva, Dimana; Hughes, Christina; Komrokji, Rami S; Zeidan, Amer M; Garcia-Manero, Guillermo.

Ann Hematol ; 102(2): 311-321, 2023 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-36635381

10.

STIMULUS-MDS2 design and rationale: a phase III trial with the anti-TIM-3 sabatolimab (MBG453) + azacitidine in higher risk MDS and CMML-2.

Zeidan, Amer M; Giagounidis, Aristoteles; Sekeres, Mikkael A; Xiao, Zhijian; Sanz, Guillermo F; Hoef, Marlies Van; Ma, Fei; Hertle, Sabine; Santini, Valeria.

Future Oncol ; 19(9): 631-642, 2023 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-37083373

11.

The ABNL-MARRO 001 study: a phase 1-2 study of randomly allocated active myeloid target compound combinations in MDS/MPN overlap syndromes.

Moyo, Tamara K; Mendler, Jason H; Itzykson, Raphael; Kishtagari, Ashwin; Solary, Eric; Seegmiller, Adam C; Gerds, Aaron T; Ayers, Gregory D; Dezern, Amy E; Nazha, Aziz; Valent, Peter; van de Loosdrecht, Arjan A; Onida, Francesco; Pleyer, Lisa; Cirici, Blanca Xicoy; Tibes, Raoul; Geissler, Klaus; Komrokji, Rami S; Zhang, Jing; Germing, Ulrich; Steensma, David P; Wiseman, Daniel H; Pfeilstöecker, Michael; Elena, Chiara; Cross, Nicholas C P; Kiladjian, Jean-Jacques; Luebbert, Michael; Mesa, Ruben A; Montalban-Bravo, Guillermo; Sanz, Guillermo F; Platzbecker, Uwe; Patnaik, Mrinal M; Padron, Eric; Santini, Valeria; Fenaux, Pierre; Savona, Michael R.

BMC Cancer ; 22(1): 1013, 2022 Sep 24.

Artigo em Inglês | MEDLINE | ID: mdl-36153475

12.

Perspective: Pivotal translational hematology and therapeutic insights in chronic myeloid hematopoietic stem cell malignancies.

Mughal, Tariq I; Pemmaraju, Naveen; Bejar, Rafael; Gale, Robert P; Bose, Prithviraj; Kiladjian, Jean-Jacques; Prchal, Josef; Royston, Daniel; Pollyea, Daniel; Valent, Peter; Brümmendorf, Tim H; Skorski, Tomasz; Patnaik, Mrinal; Santini, Valeria; Fenaux, Pierre; Kucine, Nicole; Verstovsek, Srdan; Mesa, Ruben; Barbui, Tiziano; Saglio, Guiseppe; Van Etten, Richard A.

Hematol Oncol ; 40(4): 491-504, 2022 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-35368098

13.

Overall survival of myelodysplastic syndrome patients after azacitidine discontinuation and applicability of the North American MDS Consortium scoring system in clinical practice.

Clavio, Marino; Crisà, Elena; Miglino, Maurizio; Guolo, Fabio; Ceccarelli, Manuela; Salvi, Flavia; Allione, Bernardino; Ferrero, Dario; Balleari, Enrico; Finelli, Carlo; Poloni, Antonella; Selleri, Carmine; Danise, Paolo; Cilloni, Daniela; Di Tucci, Anna Angela; Cametti, Gianni; Freilone, Roberto; Fanin, Renato; Bigazzi, Catia; Zambello, Renato; Crugnola, Monica; Oliva, Esther N; Centurioni, Riccardo; Alesiani, Francesco; Catarini, Massimo; Castelli, Andrea; Abbadessa, Antonio; Capalbo, Silvana F; Musto, Pellegrino; Angelucci, Emanuele; Santini, Valeria.

Cancer ; 127(12): 2015-2024, 2021 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-33739457

14.

Advances in myelodysplastic syndrome.

Santini, Valeria.

Curr Opin Oncol ; 33(6): 681-686, 2021 11 01.

Artigo em Inglês | MEDLINE | ID: mdl-34474438

15.

How I treat MDS after hypomethylating agent failure.

Santini, Valeria.

Blood ; 133(6): 521-529, 2019 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-30545832

16.

Neutrophil and platelet increases with luspatercept in lower-risk MDS: secondary endpoints from the MEDALIST trial.

Garcia-Manero, Guillermo; Mufti, Ghulam J; Fenaux, Pierre; Buckstein, Rena; Santini, Valeria; Díez-Campelo, María; Finelli, Carlo; Ilhan, Osman; Sekeres, Mikkael A; Zeidan, Amer M; Ito, Rodrigo; Zhang, Jennie; Rampersad, Anita; Sinsimer, Daniel; Backstrom, Jay T; Platzbecker, Uwe; Komrokji, Rami S.

Blood ; 139(4): 624-629, 2022 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-34758066

17.

Longer-term benefit of luspatercept in transfusion-dependent lower-risk myelodysplastic syndromes with ring sideroblasts.

Zeidan, Amer M; Platzbecker, Uwe; Garcia-Manero, Guillermo; Sekeres, Mikkael A; Fenaux, Pierre; DeZern, Amy E; Greenberg, Peter L; Savona, Michael R; Jurcic, Joseph G; Verma, Amit K; Mufti, Ghulam J; Buckstein, Rena; Santini, Valeria; Shetty, Jeevan K; Ito, Rodrigo; Zhang, Jennie; Zhang, George; Ha, Xianwei; Backstrom, Jay T; Komrokji, Rami S.

Blood ; 140(20): 2170-2174, 2022 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-35797468

18.

Allogeneic Hematopoietic Stem Cell Transplantation Following the Use of Hypomethylating Agents among Patients with Relapsed or Refractory AML: Findings from an International Retrospective Study.

Stahl, Maximilian; DeVeaux, Michelle; Montesinos, Pau; Itzykson, Raphaël; Ritchie, Ellen K; Sekeres, Mikkael A; Majhail, Navneet; Barnard, John; Podoltsev, Nikolai A; Brunner, Andrew M; Komrokji, Rami S; Bhatt, Vijaya R; Al-Kali, Aref; Cluzeau, Thomas; Santini, Valeria; Roboz, Gail J; Fenaux, Pierre; Litzow, Mark; Fathi, Amir T; Perreault, Sarah; Kim, Tae Kon; Prebet, Thomas; Vey, Norbert; Verma, Vivek; Kobbe, Guido; Bergua, Juan; Serrano, Josefina; Gore, Steven D; Zeidan, Amer M.

Biol Blood Marrow Transplant ; 24(8): 1754-1758, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29649620

19.

PIEZO1 mutations impact on early clinical manifestations of myelodysplastic syndromes.

Attardi, Enrico; Andolfo, Immacolata; Russo, Roberta; Tiberi, Lucia; Raddi, Marco Gabriele; Rosato, Barbara Eleni; Marra, Roberta; Formicola, Daniela; Del Giudice, Federica; Brogi, Alice; Consagra, Angela; Amato, Cristina; Sanna, Alessandro; Artuso, Rosangela; Iolascon, Achille; Santini, Valeria.

Am J Hematol ; 98(4): E72-E75, 2023 04.

Artigo em Inglês | MEDLINE | ID: mdl-36695705

20.

Iron-chelating therapy with deferasirox in transfusion-dependent, higher risk myelodysplastic syndromes: a retrospective, multicentre study.

Musto, Pellegrino; Maurillo, Luca; Simeon, Vittorio; Poloni, Antonella; Finelli, Carlo; Balleari, Enrico; Ricco, Alessandra; Rivellini, Flavia; Cortelezzi, Agostino; Tarantini, Giuseppe; Villani, Oreste; Mansueto, Giovanna; Milella, Maria R; Scapicchio, Daniele; Marziano, Gioacchino; Breccia, Massimo; Niscola, Pasquale; Sanna, Alessandro; Clissa, Cristina; Voso, Maria T; Fenu, Susanna; Venditti, Adriano; Santini, Valeria; Angelucci, Emanuele; Levis, Alessandro.

Br J Haematol ; 177(5): 741-750, 2017 06.

Artigo em Inglês | MEDLINE | ID: mdl-28419408

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