High SARS-CoV-2 Prevalence among Healthcare Workers in Cochabamba, Bolivia.

Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. The aim of the study was to estimate the SARS-CoV-2 seroprevalence among HCWs in Cochabamba, Bolivia and to determine the potential risk factors. In January 2021, a cross-sectional SARS-CoV-2 seroprevalence study was conducted in 783 volunteer clinical and non-clinical HCWs in tertiary care facilities. It was based on IgG detection using ELISA, chemiluminiscence, and seroneutralisation tests from dried blood spots. Analysis revealed a high seroprevalence (43.4%) of SARS-CoV-2 IgG antibodies. The combination of anosmia and ageusia (OR: 68.11; 95%-CI 24.83-186.80) was predictive of seropositivity. Belonging to the cleaning staff (OR: 1.94; 95%-CI 1.09-3.45), having more than two children in the same house (OR: 1.74; 95%-CI 1.12-2.71), and having been in contact with a close relative with COVID-19 (OR: 3.53; 95%-CI 2.24-5.58) were identified as risk factors for seropositivity in a multivariate analysis. A total of 47.5% of participants had received medication for COVID-19 treatment or prevention, and only ~50% of symptomatic subjects accessed PCR or antigenic testing. This study confirms a massive SARS-CoV-2 attack rate among HCWs in Cochabamba by the end of January 2021. The main risk factors identified are having a low-skilled job, living with children, and having been in contact with an infected relative in the household.

Síndrome de coreelia de lange síndrome de brachmann-de lange / Fallopian tube carcinoma case presentation

Aún en nuestros días no se puede afirmar a ciencia cierta cual es la etiología del Síndrome de Cornelia de Lange aunque día a día se realizan avances en ese aspecto. El diagnóstico es clínico basándose en reconocer oportunamente los rasgos fenotípicos faciales característicos, retardo del crecimiento intrauterino y postnatal, anormalidades en las extremidades, y retraso mental. El rango y la severidad de estas alteraciones pueden variar mucho de unos casos a otros. En razón de la las múltiples necesidades y posibles complicaciones el manejo de estos pacientes debe ser multidisciplinario. Se presenta el caso de un niño admitido en el servicio de pediatría, del Hospital del niño Manuel Ascencio Villarroel de Cochabamba, Bolivia.

In our days it is not even possible to be affirmed for sure which is the etiology of the Cornelia de Lange's Syndrome although day to day advances are made in that aspect. The diagnostic is clinical being based on recognizing the fenotípics characteristic of face, retardation of the intrauterine and postnatal growth, abnormalities in the extremities, and mental delay. The rank and the severity of these alterations can vary much some cases to others. In regard to the multiple necessities and possible complications handling of these patients it must be multidisciplinary. The case of a boy admitted in the service of pediatric appears, of the Hospital del niño Manuel Ascencio Villarroel de Cochabamba, Bolivia.